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NCT06458075 · ClinicalTrials.gov registry record · NA
Intervention to Improve Communication and Medication Adherence in Lupus
A NA study of Systemic Lupus Erythematosus, sponsored by Duke University.
- Recruiting
- Registry status
- NA
- Development phase
- 480
- Enrollment target
- 1
- Study location
NCT06458075: Recruiting NA study of Systemic Lupus Erythematosus, sponsored by Duke University.
NCT06458075 is a NA study of Systemic Lupus Erythematosus that is actively recruiting participants, run by Duke University. The registered enrollment target is 480 participants, above the 376-participant average among 99 other Systemic Lupus Erythematosus trials with a reported enrollment target (28% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06458075, a NA study of Systemic Lupus Erythematosus, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- NA
- Development phase
- 480 participants
- Enrollment target
- 1
- Study location
Study Summary
CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE). The purpose of this study is to optimize the culturally appropriate delivery and test the effect of the CO-LEAD intervention, which includes the following: 1. clinicians will be provided with a program to teach them to use effective communication strategies with patients to review real-time pharmacy refill date, engage and formulate solutions to adherence barriers, and collaboratively overcome adherence barriers. 2. use of a reliable and valid patient-reported measure of the extent of and reasons for nonadherence that helps patients identify and communicate their adherence barriers with clinicians proactively, efficiently, and comprehensively.
Primary Outcome
Proportion of SLE patient visits in which a nonjudgmental, patient-centered adherence discussion took place as determined by analysis of clinic visit audio recordings
Conditions Studied
Interventions
- BEHAVIORAL CO-LEAD
Study Locations (1)
North Carolina
- Duke University - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 480 participants |
| Start Date | 2024-07-01 |
| Est. Completion | 2028-12 |
| Phase | NA |
What NCT06458075 shows while recruiting
NCT06458075 is an interventional study that assigns participants to a tested intervention. The registered 480 participants enrollment target is mid-sized for trials with a published cap, above the 376-participant average among 99 other Systemic Lupus Erythematosus trials with a reported enrollment target (28% higher).
The record links to 1 condition, with Systemic Lupus Erythematosus appearing as the primary indexed condition, and to 1 intervention - of which CO-LEAD is the first listed.
NCT06458075 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06458075 about?
NCT06458075 is a clinical study titled "Intervention to Improve Communication and Medication Adherence in Lupus". CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE). The purpose of this study is to optimize the culturally appropriate delivery and test the effect of the CO-LEAD intervention, which includes the foll...
What is the current status of trial NCT06458075?
This trial is currently recruiting. It is a NA study. The enrollment target is 480 participants. The study started on 2024-07-01. Estimated completion is 2028-12.
What conditions does trial NCT06458075 study?
This clinical trial studies the following conditions: Systemic Lupus Erythematosus.
What interventions are being tested in trial NCT06458075?
The interventions under investigation include: CO-LEAD (BEHAVIORAL).
Who is sponsoring clinical trial NCT06458075?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06458075 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Systemic Lupus Erythematosus
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06458075's enrollment target sits among peer trials
480 17th of 99 higher than 83 of 99 other Systemic Lupus Erythematosus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Systemic Lupus Erythematosus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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