Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 3 of 35
ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials
NCT06141993
IMPRoving Outcomes in Vascular DisEase - Aortic Dissection
NCT06087029
Personalized Nutrition to Improve Recovery in Trauma
NCT06065202
Neuromodulation of Memory in Aging
NCT05460468
A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial
NCT06069726
SS-HH-OCT as a Novel Diagnostic Modality for Early-Onset Retinal Dystrophies (EORDs)
NCT06177977
Project humAn dieTary daTa rEtuRN
NCT06266689
Trans-Rectal Ultrasound of the Female Pelvis for Real-Time MRI-US Fusion Based Needle Tracking
NCT05977621
Optimize Pediatric OCT Imaging
NCT06139523
Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking
NCT05665465
Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2
NCT06139458
Oxygen Toxicity: Mechanisms in Humans
NCT05761756
Mobile Neurofeedback for Low Back Pain
NCT05669027
Testing a Device for Automatically TRacking Urine and STool in an Inpatient HCT Setting (Project TRUST)
NCT05520346
The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions
NCT04140344
COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children
NCT06164028
MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants
NCT05929898
Inspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma
NCT05608668
SenseToKnow Autism Screening Device Validation Study
NCT05874466
Neuroimaging of Opioid Phase (OPAL)
NCT05905419
Risk Stratification in Children With Concussion
NCT05825027
Neurostimulation Versus Therapy for Problems With Emotions
NCT05712057
CIED Infection Quality Initiative Demonstration Project
NCT05471973
Janus Kinase-STAT Inhibition to Reduce APOL1 Associated Kidney Disease
NCT05237388
Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes
NCT05540704
REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19
NCT05218083
Impact of Enhanced Daily Disinfection on Environmental Contamination in Hospital Rooms
NCT05739955
Enhancing Wellness Through Affirming Services and Education
NCT05700474
Parks & Pediatrics Fit Together
NCT05455190
Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors
NCT05480644
Prototyping a Device for Automating Stool and Urine Output Tracking
NCT05438199
The WISER Study: Web Based Methods for Enhancing Resilience
NCT05636072
Latino Teen Depression Treatment Study
NCT05499182
Cardiac Outcomes With Near-Complete Estrogen Deprivation
NCT05309655
Ventripoint Single Ventricle Study
NCT05262907
Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
NCT05129345
Mechanisms of Disease R/R in CAR-T for Hematologic Malignancies
NCT05397132
Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women
NCT04985903
Virtual Reality Visual Field Testing as an Alternative in Childhood Eye Disease
NCT05150197
Development & Validation of Preoperative Objective Physiological Evaluation
NCT05092126
Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
NCT04209504
Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
NCT05055830
Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
NCT05120635
A Feasibility Study Utilizing Immune Recall to Increase Response to Checkpoint Therapy
NCT05077137
Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)
NCT04995341
Exercise and Soft Tissue Sarcoma
NCT04921917
Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx
NCT04667585
Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension
NCT04454203
Prebiotic Galacto-oligosaccharide and Acute GVHD
NCT04373057
Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients
NCT04933435
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.