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NCT07566260 · ClinicalTrials.gov registry record · NA
Stress and Menstrual Health
A NA study, sponsored by Duke University.
- Recruiting
- Registry status
- NA
- Development phase
- 600
- Enrollment target
NCT07566260: Recruiting NA study, sponsored by Duke University.
NCT07566260 is a NA study that is actively recruiting participants, run by Duke University. The registered enrollment target is 600 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07566260, a NA study, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- NA
- Development phase
- 600 participants
- Enrollment target
Study Summary
The goal of this experimental study is to determine how stressors that do not directly impact energy state or energy demands (hereafter called "non-energetic stressors") affect reproductive health in pre-menopausal women. It aims to do this by answering the following main questions: Do non-energetic stressors create a stress response? How does the stress response impact sex hormone concentration and thus menstrual dysfunction? If stress caused by non-energetic stressors does impact sex hormone concentration, does it do so primarily at the level of the brain or the level of the ovary? Participants will be enrolled in this study for 6 months. For two of these months, they will undergo a short stress intervention and provide samples to measure hormone concentration and total energy expenditure.
Primary Outcome
TDEE (kcal) will be measured over a 7-day period during the Baseline and first Intervention month using the doubly-labeled water (DLW) method. DLW is a safe and reliable method for capturing free-living TDEE and has been validated for human studies. The DLW method adds a known amount of stable isotopes, oxygen-18 (18O) and deuterium (2H), to a participant's total body water (TBW) via ingestion and then measures the depletion rate of these isotopes as they are removed from the body via urine and
Interventions
- OTHER Heat stress
- OTHER Sleep stress
- OTHER Exercise stress
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2026-05-28 |
| Est. Completion | 2029-08 |
| Phase | NA |
What NCT07566260 shows while recruiting
NCT07566260 is an interventional study that assigns participants to a tested intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (57% lower).
The record links to 0 conditions, and to 3 interventions - of which Heat stress is the first listed.
NCT07566260 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07566260 about?
NCT07566260 is a clinical study titled "Stress and Menstrual Health". The goal of this experimental study is to determine how stressors that do not directly impact energy state or energy demands (hereafter called "non-energetic stressors") affect reproductive health in pre-menopausal women. It aims to do this by answering the following main questions: Do non-energetic...
What is the current status of trial NCT07566260?
This trial is currently recruiting. It is a NA study. The enrollment target is 600 participants. The study started on 2026-05-28. Estimated completion is 2029-08.
What interventions are being tested in trial NCT07566260?
The interventions under investigation include: Heat stress (OTHER), Sleep stress (OTHER), Exercise stress (OTHER).
Who is sponsoring clinical trial NCT07566260?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07566260's enrollment target sits among peer trials
600 162nd of 2000 higher than 1,827 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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