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NCT07264790 · ClinicalTrials.gov registry record · Phase 1
Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon
A Phase 1 study, sponsored by Duke University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
NCT07264790 is a Phase 1 study that is actively recruiting participants, run by Duke University. The registered enrollment target is 25 participants.
The verdict
NCT07264790, a Phase 1 study, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
Study Summary
The purpose of the study is to determine whether pharmacologic delay using minoxidil in patients undergoing bilateral risk reducing mastectomy with reconstruction could achieve improvement in flap perfusion and flap viability at the time of surgery. Patients will undergo randomization of their breasts to determine which breast will receive the experimental intervention and which breast will serve as the internal control (receive placebo). The experimental breast will receive the novel pharmacologic delay treatment, 5% minoxidil, while the internal control breast will receive the current standard of care, which does not include any topical application prior to surgery - a placebo control will be used. This will be a triple-blind study, where both the participants and investigators will be blinded to which breast will receive the intervention. The patients will receive two bottles "compound A" and "compound B" with directions from the pharmacy for which compound to apply to each breast. Product will be applied for 2 weeks prior to planned surgery. Surgery will proceed without any changes to standard practice.
Interventions
- DRUG Minoxidil
- DRUG Hair mousse
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2026-03-16 |
| Est. Completion | 2027-09 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07264790
The ClinicalTrials.gov registry entry for NCT07264790 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Minoxidil is the first listed.
NCT07264790 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07264790 about?
NCT07264790 is a clinical study titled "Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon". The purpose of the study is to determine whether pharmacologic delay using minoxidil in patients undergoing bilateral risk reducing mastectomy with reconstruction could achieve improvement in flap perfusion and flap viability at the time of surgery. Patients will undergo randomization of their breas...
What is the current status of trial NCT07264790?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2026-03-16. Estimated completion is 2027-09.
What interventions are being tested in trial NCT07264790?
The interventions under investigation include: Minoxidil (DRUG), Hair mousse (DRUG).
Who is sponsoring clinical trial NCT07264790?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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