Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06638892 · ClinicalTrials.gov registry record · NA
Using PrEP, Doing It for Ourselves
A NA study of HIV Prevention and PrEP, sponsored by Duke University.
- Recruiting
- Registry status
- NA
- Development phase
- 1,000
- Enrollment target
- 1
- Study location
NCT06638892: Recruiting NA study of HIV Prevention and PrEP, sponsored by Duke University.
NCT06638892 is a NA study of HIV Prevention and PrEP that is actively recruiting participants, run by Duke University. The registered enrollment target is 1,000 participants, above the 351-participant average among 32 other HIV Prevention trials with a reported enrollment target (185% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06638892, a NA study of HIV Prevention and PrEP, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to test a new online program called UPDOs Protective Styles to help people in the southeastern United States learn about and start using PrEP (pre-exposure prophylaxis), a medicine that helps prevent HIV. The study focuses on people who may be at higher risk for HIV and have not had equal access to PrEP. The main questions it aims to answer are: Does UPDOs help more people trust and understand PrEP? Does UPDOs increase the number of people who start and continue using PrEP? Researchers will compare two groups: One group will use UPDOs, which includes six weekly videos, blog discussions, and access to telehealth services through Q Care Plus. The other group will receive standard HIV prevention materials from the CDC. Participants will: Be recruited from 32 beauty salons in areas with high HIV rates. Complete surveys at the start of the study and again at 6, 12, 24, 32, and 52 weeks. Have access to HIV testing and PrEP prescriptions through Q Care Plus. This study will also look at how well the program works in different communities and how easy it is to use and share.
Primary Outcome
The PrEP Contemplation Ladder is a 1-item survey designed to measure Motivational PrEP Cascade (MPC) stages of behavior change that represent one's PrEP intentions by a score of 1-10. Scores correspond to MPC stages. Lower numbers indicate PrEP is not being used to prevent HIV and the participant is not really thinking of ever starting to use PrEP. Higher numbers indicate that PrEP is being used daily and the participant is returning for provider checkups and HIV/STI testing every 3 months, as r
Conditions Studied
Interventions
- OTHER Standard of Care
- BEHAVIORAL Using PrEP, Doing it for Ourselves (UPDOs)
Study Locations (1)
North Carolina
- Duke University School of Nursing - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2026-02-13 |
| Est. Completion | 2030-01 |
| Phase | NA |
What NCT06638892 shows while recruiting
NCT06638892 is an interventional study that assigns participants to a tested intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 351-participant average among 32 other HIV Prevention trials with a reported enrollment target (185% higher).
The record links to 2 conditions, with HIV Prevention appearing as the primary indexed condition, and to 2 interventions - of which Standard of Care is the first listed.
NCT06638892 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06638892 about?
NCT06638892 is a clinical study titled "Using PrEP, Doing It for Ourselves". The goal of this clinical trial is to test a new online program called UPDOs Protective Styles to help people in the southeastern United States learn about and start using PrEP (pre-exposure prophylaxis), a medicine that helps prevent HIV. The study focuses on people who may be at higher risk for HI...
What is the current status of trial NCT06638892?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,000 participants. The study started on 2026-02-13. Estimated completion is 2030-01.
What conditions does trial NCT06638892 study?
This clinical trial studies the following conditions: HIV Prevention, PrEP.
What interventions are being tested in trial NCT06638892?
The interventions under investigation include: Standard of Care (OTHER), Using PrEP, Doing it for Ourselves (UPDOs) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06638892?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06638892 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for HIV Prevention
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06638892's enrollment target sits among peer trials
1,000 3rd of 32 higher than 30 of 32 other HIV Prevention trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV Prevention trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Client-Centered Care Coordination for Black Men Who Have Sex With Men
RECRUITING · NA
-
Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals
RECRUITING · NA
-
Intervention to Enhance PrEP Persistence
RECRUITING · NA
-
WePrEP: Developing a PrEP Shared Decision-making Tool for Transgender Women
RECRUITING · NA
-
Hybrid Evaluation of a Home-based HIV Pre-exposure Prophylaxis Program
RECRUITING · NA
-
Digital Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in YTW
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00018044 · 1,000 participants
Study of Mycobacterial Infections
- NCT01036581 · 1,000 participants · NA
Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging
- NCT01192048 · 1,000 participants
Genetics of Congenital Heart Disease
- NCT01553214 · 1,000 participants · Phase 4
Improving White Blood Cell Collection From Healthy Donors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI