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NCT04824027 · ClinicalTrials.gov registry record · NA
Breast Elasticity Imaging During Neoadjuvant Chemotherapy
A NA study of Breast Cancer, sponsored by Columbia University.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT04824027: Recruiting NA study of Breast Cancer, sponsored by Columbia University.
NCT04824027 is a NA study of Breast Cancer that is actively recruiting participants, run by Columbia University. The registered enrollment target is 50 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04824027, a NA study of Breast Cancer, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
For this study, the investigators propose investigation of a new imaging technique, Harmonic Motion Imaging (HMI), and the evaluation of its potential role in prediction of breast cancer response to neoadjuvant chemotherapy (NACT). The investigators hypothesize that changes in HMI parameters will predict response to neoadjuvant systemic therapy in early-stage breast cancer.
Primary Outcome
* Repeated measures analysis of variance (ANOVA) will be performed to investigate the overall differences in HMI measurements within the tumor and surrounding tissue between responders (pCR and RCB1) and non-responders (RCB2). This relative percent change in tumor stiffness is directly related to HMI measurements. * Pathologic response will be assessed by the Residual Cancer Burden (RCB) score, a continuous and categorical measure of pathologic response and an independent predictor of disease fr
Conditions Studied
Interventions
- PROCEDURE Harmonic motion imaging
Study Locations (1)
New York
- Columbia University Irving Medical Center/NYP - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2021-06-14 |
| Est. Completion | 2026-05 |
| Phase | NA |
What NCT04824027 shows while recruiting
NCT04824027 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Harmonic motion imaging is the first listed.
NCT04824027 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT04824027 about?
NCT04824027 is a clinical study titled "Breast Elasticity Imaging During Neoadjuvant Chemotherapy". For this study, the investigators propose investigation of a new imaging technique, Harmonic Motion Imaging (HMI), and the evaluation of its potential role in prediction of breast cancer response to neoadjuvant chemotherapy (NACT). The investigators hypothesize that changes in HMI parameters will pr...
What is the current status of trial NCT04824027?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2021-06-14. Estimated completion is 2026-05.
What conditions does trial NCT04824027 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT04824027?
The interventions under investigation include: Harmonic motion imaging (PROCEDURE).
Who is sponsoring clinical trial NCT04824027?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04824027 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04824027's enrollment target sits among peer trials
50 789th of 1224 higher than 410 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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