Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Effect of Giving Reduced Fluid in Children After Trauma
NCT04201704 · View on ClinicalTrials.gov ↗
Study Summary
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volumes of IV fluid. Recent studies in adults show that patients actually do better by giving less fluid. The investigators do not know if this is true in children and this study is designed to answer that question and provide guidelines for IV fluid management in children after trauma.
Conditions Studied
Interventions
- OTHER Balanced crystalloid solution volume administration
- OTHER Packed Erythrocytes Units, Blood Product Unit volume
- OTHER Plasma volume
- OTHER Platelets volume
Study Locations (4)
New York
- John R. Oishei Children's Hospital of Buffalo — Buffalo
- Columbia University Irving Medical Center NewYork-Presbyterian Morgan Stanley Children's Hospital — New York
- University of Rochester, Golisano Children's Hospital — Rochester
Tennessee
- Le Bonheur Children's Hospital — Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2018-08-27 |
| Est. Completion | 2026-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04201704
The ClinicalTrials.gov registry entry for NCT04201704 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 875 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Critical Illness appearing as the primary indexed condition, and to 4 interventions — of which Balanced crystalloid solution volume administration is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04201704 reports 4 study locations spanning 2 distinct geographic areas — top geographies include New York, Tennessee. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04201704 about?
NCT04201704 is a clinical study titled "Effect of Giving Reduced Fluid in Children After Trauma". This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volum...
What is the current status of trial NCT04201704?
This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2018-08-27. Estimated completion is 2026-09.
What conditions does trial NCT04201704 study?
This clinical trial studies the following conditions: Critical Illness, Wounds and Injuries, Pediatrics, General Surgery, Fluid Therapy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04201704?
The interventions under investigation include: Balanced crystalloid solution volume administration (OTHER), Packed Erythrocytes Units, Blood Product Unit volume (OTHER), Plasma volume (OTHER), Platelets volume (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04201704?
This trial is sponsored by Columbia University, which has 875 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04201704 being conducted?
This trial has 4 study locations across New York, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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