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NCT04201704 · ClinicalTrials.gov registry record · NA
Effect of Giving Reduced Fluid in Children After Trauma
A NA study of Critical Illness and Wounds and Injuries, sponsored by Columbia University.
- Recruiting
- Registry status
- NA
- Development phase
- 250
- Enrollment target
- 4
- Study locations
NCT04201704: Recruiting NA study of Critical Illness and Wounds and Injuries, sponsored by Columbia University.
NCT04201704 is a NA study of Critical Illness and Wounds and Injuries that is actively recruiting participants, run by Columbia University. The registered enrollment target is 250 participants, below the 3,136-participant average among 91 other Critical Illness trials with a reported enrollment target (92% lower). The trial reports 4 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04201704, a NA study of Critical Illness and Wounds and Injuries, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 250 participants
- Enrollment target
- 4
- Study locations
Study Summary
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volumes of IV fluid. Recent studies in adults show that patients actually do better by giving less fluid. The investigators do not know if this is true in children and this study is designed to answer that question and provide guidelines for IV fluid management in children after trauma.
Primary Outcome
Total number of complications defined as pulmonary edema, hemorrhage, deep cavity infection, anastomotic dehiscence, thrombosis, death, superficial wound infection, ileus, and pneumonia.
Conditions Studied
Interventions
- OTHER Balanced crystalloid solution volume administration
- OTHER Packed Erythrocytes Units, Blood Product Unit volume
- OTHER Plasma volume
- OTHER Platelets volume
Study Locations (4)
New York
- John R. Oishei Children's Hospital of Buffalo - Buffalo
- Columbia University Irving Medical Center NewYork-Presbyterian Morgan Stanley Children's Hospital - New York
- University of Rochester, Golisano Children's Hospital - Rochester
Tennessee
- Le Bonheur Children's Hospital - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2018-08-27 |
| Est. Completion | 2026-09 |
| Phase | NA |
What NCT04201704 shows while recruiting
NCT04201704 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 3,136-participant average among 91 other Critical Illness trials with a reported enrollment target (92% lower).
The record links to 5 conditions, with Critical Illness appearing as the primary indexed condition, and to 4 interventions - of which Balanced crystalloid solution volume administration is the first listed.
NCT04201704 reports a single indexed study location in New York, Tennessee.
Frequently Asked Questions
What is clinical trial NCT04201704 about?
NCT04201704 is a clinical study titled "Effect of Giving Reduced Fluid in Children After Trauma". This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volum...
What is the current status of trial NCT04201704?
This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2018-08-27. Estimated completion is 2026-09.
What conditions does trial NCT04201704 study?
This clinical trial studies the following conditions: Critical Illness, Wounds and Injuries, Pediatrics, General Surgery, Fluid Therapy.
What interventions are being tested in trial NCT04201704?
The interventions under investigation include: Balanced crystalloid solution volume administration (OTHER), Packed Erythrocytes Units, Blood Product Unit volume (OTHER), Plasma volume (OTHER), Platelets volume (OTHER).
Who is sponsoring clinical trial NCT04201704?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04201704 being conducted?
This trial has 4 study locations across New York, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04201704's enrollment target sits among peer trials
250 46th of 91 higher than 45 of 91 other Critical Illness trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Critical Illness trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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