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NCT03667326 · ClinicalTrials.gov registry record · Phase 2

Postpartum Low-Dose Aspirin and Preeclampsia

A Phase 2 study of Preeclampsia Postpartum, sponsored by Columbia University.

Recruiting
Registry status
Phase 2
Development phase
100
Enrollment target
1
Study location

NCT03667326 is a Phase 2 study of Preeclampsia Postpartum that is actively recruiting participants, run by Columbia University. The registered enrollment target is 100 participants, above the 62-participant average among 8 other Preeclampsia Postpartum trials with a reported enrollment target (61% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT03667326, a Phase 2 study of Preeclampsia Postpartum, is actively recruiting participants, sponsored by Columbia University.

RECRUITING
Registry status
Phase 2
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research study is to find out whether women with severe preeclampsia taking low-dose aspirin (LDA) for 3 weeks post-delivery will experience an improvement in endothelial function (measured as flow-mediated dilation - FMD) and severity of disease, as the effects of preeclampsia can persist postpartum. Women diagnosed with severe preeclampsia prior to delivery will be enrolled and randomized to receive either low-dose aspirin (81mg) or placebo to take daily for up to 3 weeks post-delivery. Exploratory objective includes healthy control postpartum patients without preeclampsia and not on LDA during pregnancy or postpartum in comparison with the primary study population affected by preeclampsia with severe features.

Conditions Studied

Interventions

  • DRUG Aspirin tablet
  • DRUG Placebo oral capsule

Study Locations (1)

New York

  • Columbia University Irving Medical Center - New York

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2019-07-22
Est. Completion 2026-12
Phase Phase 2

Sponsor

Columbia University

958 total trials

What the Registry Record Tells You About NCT03667326

The ClinicalTrials.gov registry entry for NCT03667326 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 62-participant average among 8 other Preeclampsia Postpartum trials with a reported enrollment target (61% higher). The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Preeclampsia Postpartum appearing as the primary indexed condition, and to 2 interventions - of which Aspirin tablet is the first listed.

NCT03667326 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT03667326 about?

NCT03667326 is a clinical study titled "Postpartum Low-Dose Aspirin and Preeclampsia". The purpose of this research study is to find out whether women with severe preeclampsia taking low-dose aspirin (LDA) for 3 weeks post-delivery will experience an improvement in endothelial function (measured as flow-mediated dilation - FMD) and severity of disease, as the effects of preeclampsia c...

What is the current status of trial NCT03667326?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2019-07-22. Estimated completion is 2026-12.

What conditions does trial NCT03667326 study?

This clinical trial studies the following conditions: Preeclampsia Postpartum.

What interventions are being tested in trial NCT03667326?

The interventions under investigation include: Aspirin tablet (DRUG), Placebo oral capsule (DRUG).

Who is sponsoring clinical trial NCT03667326?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03667326 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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