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NCT05680558 · ClinicalTrials.gov registry record · Phase 2

Photopheresis in Early-stage Mycosis Fungoides

A Phase 2 study of Cutaneous T Cell Lymphoma and Mycosis Fungoides, sponsored by Columbia University.

Recruiting
Registry status
Phase 2
Development phase
74
Enrollment target
1
Study location

NCT05680558 is a Phase 2 study of Cutaneous T Cell Lymphoma and Mycosis Fungoides that is actively recruiting participants, run by Columbia University. The registered enrollment target is 74 participants, above the 64-participant average among 23 other Cutaneous T Cell Lymphoma trials with a reported enrollment target (16% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT05680558, a Phase 2 study of Cutaneous T Cell Lymphoma and Mycosis Fungoides, is actively recruiting participants, sponsored by Columbia University.

RECRUITING
Registry status
Phase 2
Development phase
74 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine whether photopheresis therapy can be used to improve the clinical course of early stage cutaneous T-cell lymphoma (CTCL). Currently, photopheresis is performed as a palliative treatment for late stage CTCL. However, recent studies have demonstrated that patients with early stage CTCL may have markers in their blood which were previously observed primarily in late stage disease, such as clonal T cell populations. Considering these findings, the study aims to investigate whether photopheresis therapy may be used earlier in the disease course to produce a clinical response.

Interventions

  • DRUG UVADEX® (methoxsalen) Sterile Solution in conjunction with the THERAKOS® CELLEX Photopheresis
  • DEVICE THERAKOS® CELLEX photopheresis system

Study Locations (1)

New York

  • Herbert Irving Pavilion - New York

Trial Details

FieldValue
Enrollment Target 74 participants
Start Date 2021-05-08
Est. Completion 2027-07
Phase Phase 2

Sponsor

Columbia University

958 total trials

What the Registry Record Tells You About NCT05680558

The ClinicalTrials.gov registry entry for NCT05680558 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 64-participant average among 23 other Cutaneous T Cell Lymphoma trials with a reported enrollment target (16% higher). The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Cutaneous T Cell Lymphoma appearing as the primary indexed condition, and to 2 interventions - of which UVADEX® (methoxsalen) Sterile Solution in conjunction with the THERAKOS® CELLEX Photopheresis is the first listed.

NCT05680558 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT05680558 about?

NCT05680558 is a clinical study titled "Photopheresis in Early-stage Mycosis Fungoides". The purpose of this study is to determine whether photopheresis therapy can be used to improve the clinical course of early stage cutaneous T-cell lymphoma (CTCL). Currently, photopheresis is performed as a palliative treatment for late stage CTCL. However, recent studies have demonstrated that pati...

What is the current status of trial NCT05680558?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 74 participants. The study started on 2021-05-08. Estimated completion is 2027-07.

What conditions does trial NCT05680558 study?

This clinical trial studies the following conditions: Cutaneous T Cell Lymphoma, Mycosis Fungoides.

What interventions are being tested in trial NCT05680558?

The interventions under investigation include: UVADEX® (methoxsalen) Sterile Solution in conjunction with the THERAKOS® CELLEX Photopheresis (DRUG), THERAKOS® CELLEX photopheresis system (DEVICE).

Who is sponsoring clinical trial NCT05680558?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05680558 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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