Children's National Research Institute
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Children's National Research Institute sits in the top decile of US sponsors by registered trial count (#256 of 15,742 sponsors by registered trial count).
Children's National Research Institute: 92 sponsored US clinical trials, 35 recruiting.
Children's National Research Institute sponsors 92 registered US clinical trials on ClinicalTrials.gov, 35 of them currently recruiting, and 41 completed. 5 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 3 trials.
Top-decile sponsor footprint
Children's National Research Institute ranks in the top decile of sponsors by registered trial count (#256 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
41 of 42 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (97.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
92 total, page 1 of 2
Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)
NCT07172958
A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.
NCT07017816
Characterization of Acute Pain
NCT07336264
Pragmatic Clinic-Based Trial of a Mindfulness Based Intervention for Mood Concerns in Youth With Type 1 Diabetes
NCT06618027
Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease
NCT06770010
The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
NCT06623981
Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols
NCT06429982
Efficacy of a Novel Prototype Gastrostomy Tube Anchor Dressing
NCT07115134
Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)
NCT06193759
Virtual Reality During Lumbar Punctures in Acute Lymphoblastic Leukemia
NCT06722638
Using Mobile Health (mHealth) to Improve STI Treatment Adherence Among Adolescents
NCT04372485
Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody
NCT06358638
Navigating Pregnancy and Parenthood With Lyme Disease
NCT06397794
Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment
NCT06266455
Augmented Reality For MRI-Guided Interventions
NCT06224933
Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects
NCT06036199
Therapeutic Endpoint in Pediatric IBD Conditions
NCT06065228
Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure
NCT06026969
Evaluation of The Food Allergy Mastery Program
NCT06034678
Feasibility/Acceptability of Attentional-Control Training in Survivors
NCT05528939
Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic Trial
NCT04372875
PAINED: Project Addressing INequities in the Emergency Department
NCT05488080
International Rare Brain Tumor Registry
NCT05697874
Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease
NCT05099874
Omalizumab Before Onset of Exacerbations
NCT05332067
Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts
NCT04691622
Augmented Reality Ultrasound Guidance
NCT05964439
Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors
NCT05238792
T Cell Therapy Opposing Novel COVID-19 Infection in Immunocompromised Patients
NCT05141058
Physiologic Measure of VIPN
NCT04786977
Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
NCT04833465
Systemic Biomarkers of Brain Injury From Hyperammonemia
NCT04602325
MRI to Predict Rejection and Failure in Transplant and Cardiomyopathy Patients
NCT03822442
Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders
NCT02935283
Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
NCT01106794
Rare Group Problem Management Plus
NCT06548022
Growth Hormone in a Patient With a Dominant-Negative GHR Mutation
NCT05382637
The DC Mother-Infant Behavioral Wellness Program
NCT05345834
PedBot Ankle Rehablitation
NCT05825508
Research on Optimizing the Use of Technology With Education
NCT05564481
Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD
NCT05131659
Pediatric COVID Outcomes Study (PECOS)
NCT04830852
Central Blood Pressure and Pulse Wave Velocity in Kidney Transplant Recipients
NCT04212143
MR-HIFU Treatment of Painful Osteoid Osteoma
NCT04658771
Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1
NCT03820778
T-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic Stem Cell Transplantation
NCT03180216
Research Study Utilizing Expanded Multi-antigen Specific Lymphocytes for the Treatment of Solid Tumors
NCT02789228
Efficacy of Amicar for Children Having Craniofacial Surgery
NCT02229968
Technical Development for Pediatric Cardiovascular MRI
NCT02892136
Use of Equity Report Cards to Mitigate Disparities in Emergency Medical Services (EMS) Care for Injured Children
NCT06531421
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 8 |
| Phase 3 | 2 |
| Phase 4 | 3 |
What is open in the Children's National Research Institute pipeline
35 recruiting of 92 indexed (38% open); 41 completed (45%).
Phase mix: 5 late (III/IV) vs 18 early (I/II) (early-phase heavy).
Top condition: Sickle Cell Disease (3 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Children's National Research Institute: open-pipeline peers nationwide
Peers matched on 92 registered trials and 38% open enrollment, not the therapeutic-area sidebar.
Children's National Research Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 92 trials (± recruiting share)
- Drexel University · 92 trials · 16% recruiting
- Loyola University · 92 trials · 13% recruiting
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · 93 trials · 13% recruiting
- National Institute on Alcohol Abuse and Alcoholism (NIAAA) · 93 trials · 17% recruiting
Sponsors near 38% open enrollment (± trial volume)
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · 38% recruiting · 34 trials
- Intra-Cellular Therapies · 38% recruiting · 37 trials
- Morehouse School of Medicine · 38% recruiting · 13 trials
- Northeastern University · 38% recruiting · 39 trials
Related
What to do with this Children's National Research Institute page
92 registered trials is a research-attention snapshot, not an endorsement of Children's National Research Institute or any single study.
- 35 of Children's National Research Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Sickle Cell Disease is the condition Children's National Research Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sickle Cell Disease trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Children's National Research Institute pipeline card: 92 registered trials from official public datasets.Report a data error.