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ClinicalTrials.gov 6 recruiting now official registry

Sexually Transmitted Diseases clinical trials

6 of 36 indexed Sexually Transmitted Diseases trials are currently recruiting.

36 US clinical trials · 6 currently recruiting

Sexually Transmitted Diseases is the subject of 36 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 4 of these trials.

The research picture

Sexually Transmitted Diseases has 36 registered US clinical trials, 6 of them open to new participants right now, about 17% of the total.

6
recruiting participants now
17%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
4
top sponsor: University of California, San Francisco
Phase 12Phase 24Phase 32Phase 43

Active & Recent Trials

36 total, page 1 of 1

RECRUITING NA 18,500 participants

Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic Trial

Children's National Research Institute

NCT04372875

RECRUITING NA 2,000 participants

Evaluation of Parent Toolkit 2.0 (Morehouse Family Health Study)

Child Trends

NCT06579781

RECRUITING NA 1,200 participants

Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth

ETR Associates

NCT06581536

RECRUITING NA 400 participants

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Emory University

NCT05910580

RECRUITING NA 300 participants

Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention

Public Health Foundation Enterprises

NCT04855773

RECRUITING NA 270 participants

Using Mobile Health (mHealth) to Improve STI Treatment Adherence Among Adolescents

Children's National Research Institute

NCT04372485

ACTIVE NOT RECRUITING NA 2,250 participants

Evaluation of an Adolescent Pregnancy Prevention Program; Relationship Smarts+ With Lessons From Mind Matters

Trinity Church

NCT05889689

ACTIVE NOT RECRUITING NA 752 participants

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

April M Young

NCT05657106

ACTIVE NOT RECRUITING NA 279 participants

Sexual Health Empowerment for Women's Health

University of Kansas Medical Center

NCT03984695

COMPLETED NA 3,098 participants

Engineering an Online STI Prevention Program: RCT

Penn State University

NCT04095065

COMPLETED 2,831 participants

Improving Adolescent Health Outcomes Through Preventive Care Transformation

Indiana University

NCT02244138

COMPLETED Phase 1 2,210 participants

Parents Matter!: Interventions to Promote Effective Parent-Child Communication

Centers for Disease Control and Prevention

NCT00137943

COMPLETED NA 1,450 participants

Louisville Teen Pregnancy Prevention Project

University of Louisville

NCT01411878

COMPLETED NA 1,260 participants

Personal Responsibility Education Program Innovative Strategies: Digital Initiative for Youth

University of California, San Francisco

NCT03765255

COMPLETED Phase 4 1,233 participants

Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women

Yale University

NCT00628771

COMPLETED Phase 3 1,010 participants

Reducing Sexual Risk Behaviors and Improving Health for People at a Sexually Transmitted Infection Clinic

The Miriam Hospital

NCT00947271

COMPLETED Phase 2 746 participants

A Peer-Oriented HIV Prevention Outreach Program for Individuals at High Risk for HIV and Other STIs

Johns Hopkins Bloomberg School of Public Health

NCT00183456

COMPLETED NA 600 participants

Synthetic Male Condom Slippage-Breakage Study

Church & Dwight Company

NCT05370196

COMPLETED NA 574 participants

Internet-Based Sexual Health Education for Middle School Native American Youth

The University of Texas Health Science Center, Houston

NCT01303575

COMPLETED Phase 3 530 participants

Reducing HIV & Domestic Violence Risk in Women Offenders

Multnomah County Health Department

NCT00289939

COMPLETED NA 480 participants

Protect and Connect: Couple HIV Prevention for Drug Involved Male Offenders

Columbia University

NCT01690494

COMPLETED Phase 1 341 participants

Evaluation of Many Men, Many Voices, An STD/HIV Prevention Intervention for Black MSM

Centers for Disease Control and Prevention

NCT00137631

COMPLETED Phase 2 319 participants

Safety of and Immune Response to the Human Papillomavirus (HPV) Vaccine in HIV-Infected Women

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00604175

COMPLETED NA 166 participants

Advancing HIV Prevention and Linkage to Care Among MSM With Gamification

University of California, Berkeley

NCT02946164

COMPLETED 150 participants

Preventive Sexual Health Screening Among Female-to-Male (FTM) Transgender Adult Patients

Fenway Community Health

NCT02401867

COMPLETED NA 148 participants

Acceptability, Feasibility, and Preliminary Impact of a Web-based, HIV Prevention Toolkit With Cisgender Male Couples in Lima, Peru

Florida International University

NCT05873855

COMPLETED NA 141 participants

The OPENS Trial: Offering Women PrEP (Aim 2)

University of California, San Francisco

NCT05619497

COMPLETED Phase 2 130 participants

Safety of and Immune Response to a Novel Human Papillomavirus Vaccine in HIV Infected Children

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00339040

COMPLETED Phase 2 120 participants

Addressing Heavy Alcohol Use Consumption With Kudzu

Glenn-Milo Santos

NCT03709043

COMPLETED NA 91 participants

Enhanced SexHealth Intervention to Improve Adolescent Outcomes

Children's Mercy Hospital Kansas City

NCT03341975

COMPLETED NA 75 participants

Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening

University of Michigan

NCT06100250

COMPLETED Phase 4 33 participants

Mesalamine to Reduce T Cell Activation in HIV Infection

University of California, San Francisco

NCT01090102

COMPLETED NA 33 participants

Adopting and Demonstrating the Adaptation of Prevention Techniques (ADAPT), Harlem United Community AIDS Center

Centers for Disease Control and Prevention

NCT00267410

COMPLETED NA 30 participants

CRUSH-PrEP for Women Project

University of California, San Francisco

NCT02852226

COMPLETED Phase 4 20 participants

Combo-PEP: Multipurpose Prevention of Post-Exposure Prophylaxis Regimens

Emory University

NCT04860505

COMPLETED NA 14 participants

Distress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid Dependence

Rhode Island Hospital

NCT02602795

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 2
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Sexually Transmitted Diseases Trial Landscape

36 indexed Sexually Transmitted Diseases studies · 6 recruiting (17%).

Phase mix: 5 late (III/IV) vs 6 early (I/II).

Top sponsor: University of California, San Francisco (4 trials), 9 others listed. 36 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Sexually Transmitted Diseases?

PlainTrial tracks 36 US clinical trials for Sexually Transmitted Diseases, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Sexually Transmitted Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.