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NCT06623981 · ClinicalTrials.gov registry record · NA
The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
A NA study of Depression and Asthma in Children, sponsored by Children's National Research Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06623981: Recruiting NA study of Depression and Asthma in Children, sponsored by Children's National Research Institute.
NCT06623981 is a NA study of Depression and Asthma in Children that is actively recruiting participants, run by Children's National Research Institute. The registered enrollment target is 60 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06623981, a NA study of Depression and Asthma in Children, is actively recruiting participants, sponsored by Children's National Research Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to test the effectiveness and implementation of delivering Enhanced Brief Interpersonal Psychotherapy (IPT-B), an evidence-based maternal depression treatment, to mothers of children under the age of 18 in an urban pediatric asthma clinic. Researchers will compare Enhanced IPT-B and supplemented usual care (brief care coordination). The main questions the trial aims to answer are: 1. Does Enhanced IPT-B decrease maternal depressive symptoms? 2. Does Enhanced IPT-B improve child asthma management and health outcomes (exacerbations, symptoms, control)? 3. What are the preliminary implementation outcomes of delivering Enhanced IPT-B in an urban pediatric asthma clinic?
Primary Outcome
≥ 50% reduction in depressive symptoms on the 9-item Patient Health Questionnaire (PHQ-9) at T2. The PHQ-9 score ranges from 0-27, with higher scores indicating more depressive symptoms. This variable will be dichotomized into 50% or greater reduction in depressive symptoms vs. less than 50% reduction in depressive symptoms from T1 to T2.
Conditions Studied
Interventions
- BEHAVIORAL Enhanced Brief Interpersonal Psychotherapy
- BEHAVIORAL Supplemented Usual Care
Study Locations (1)
District of Columbia
- Children's National Hospital - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-10-15 |
| Est. Completion | 2027-03-15 |
| Phase | NA |
What NCT06623981 shows while recruiting
NCT06623981 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Enhanced Brief Interpersonal Psychotherapy is the first listed.
NCT06623981 reports a single indexed study location in District of Columbia.
Frequently Asked Questions
What is clinical trial NCT06623981 about?
NCT06623981 is a clinical study titled "The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic". The goal of this clinical trial is to test the effectiveness and implementation of delivering Enhanced Brief Interpersonal Psychotherapy (IPT-B), an evidence-based maternal depression treatment, to mothers of children under the age of 18 in an urban pediatric asthma clinic. Researchers will compare ...
What is the current status of trial NCT06623981?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-10-15. Estimated completion is 2027-03-15.
What conditions does trial NCT06623981 study?
This clinical trial studies the following conditions: Depression, Asthma in Children.
What interventions are being tested in trial NCT06623981?
The interventions under investigation include: Enhanced Brief Interpersonal Psychotherapy (BEHAVIORAL), Supplemented Usual Care (BEHAVIORAL).
Who is sponsoring clinical trial NCT06623981?
This trial is sponsored by Children's National Research Institute, which has 92 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06623981 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06623981's enrollment target sits among peer trials
60 428th of 679 higher than 234 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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