Children's National Research Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Children's National Research Institute sits in the top decile of US sponsors by registered trial count (#256 of 15,742 sponsors by registered trial count).

92 total trials 35 currently recruiting 41 completed early-phase tilt top decile by trial count

Children's National Research Institute: 92 sponsored US clinical trials, 35 recruiting.

Children's National Research Institute sponsors 92 registered US clinical trials on ClinicalTrials.gov, 35 of them currently recruiting, and 41 completed. 5 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 3 trials.

Top-decile sponsor footprint

Children's National Research Institute ranks in the top decile of sponsors by registered trial count (#256 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

B 84/100

41 of 42 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (97.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

92 total, page 2 of 2

COMPLETED NA

Interventions to Promote Well-being of Nightshift Nursing Team Members

NCT05722249

COMPLETED NA

Feasibility Trial of a Mindfulness Based Intervention in Youth With Type 1 Diabetes

NCT05268393

COMPLETED Phase 2

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

NCT05302921

COMPLETED NA

Group Visits for High Risk Type 1 Diabetes (T1D)

NCT05431686

COMPLETED NA

Development and Pilot Testing of a Novel Preschool Executive Function Curriculum

NCT05135728

COMPLETED NA

A Hybrid Effectiveness-implementation Trial of a High School-based Executive Function Treatment for Autistic Youth

NCT05017779

COMPLETED NA

FACE for Children With Rare Diseases

NCT04855734

COMPLETED NA

Hybrid Closed Loop in High Risk Youth With Type 1 Diabetes

NCT04807374

COMPLETED

Sound Levels in the Pediatric Cardiac Critical Care Unit and Their Correlation With Sedation Administration, Delirium Scores and Patient Heart Rate

NCT04777695

COMPLETED NA

Preliminary Feasibility and Efficacy of Behavioral Intervention to Reduce Pain-Related Disability in Pediatric SCD

NCT04388241

COMPLETED

Accuracy of the Red Reflex Test in the Pediatric Population

NCT04125043

COMPLETED NA

Concussion Active Rehabilitation

NCT04248218

COMPLETED

Frameshift Peptides of Children With NF1

NCT04212351

COMPLETED Phase 2

Intermittent Hypoxia and Caffeine in Infants Born Preterm

NCT03321734

COMPLETED NA

Infant Car Seat Use

NCT05252299

COMPLETED NA

Improving Health Communication During the Transition From Pediatric to Adult Diabetes Care

NCT03734107

COMPLETED Phase 2

Hydroxyurea and Transfusion

NCT03644953

COMPLETED NA

Social Navigation for Adolescents in ED

NCT03239041

COMPLETED

PCORI Urea Cycle Disorder Study

NCT02740153

COMPLETED NA

GPS (Giving Parents Support): Parent Navigation After NICU Discharge

NCT02643472

COMPLETED NA

The Effects of Aromatherapy on the Incidence and Severity of Acute Pain

NCT03122574

COMPLETED NA

Executive Function Intervention for High School Students With ASD

NCT03199937

COMPLETED NA

Safety and Feasibility of MR-Guided High Intensity Focused Ultrasound (MR-HIFU) Ablation of Osteoid Osteoma in Children

NCT02349971

COMPLETED NA

Improvement of STI Detection in Adolescent Emergency Department Patients

NCT02509572

COMPLETED NA

MRI Assessment of Arrythmia Ablation Lesions

NCT02761343

COMPLETED

Pilot Study of Cardiac MR in Patients With Muscular Dystrophy

NCT02921321

COMPLETED NA

Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care

NCT01775436

COMPLETED Phase 1

Cytotoxic T Cells to Prevent Virus Infections

NCT01923766

COMPLETED

Myocardial Perfusion and Scarring in Adults With Congenital Heart Disease

NCT02861365

COMPLETED

Bedside Lung Ultrasound in Young Children Presenting to the Emergency Department (ED) With Wheezing

NCT01452945

COMPLETED

Fentanyl Metabolism in Obese Adolescents

NCT01955993

COMPLETED NA

Oral Galactose in Children With Steroid Resistant Nephrotic Syndrome

NCT01113385

COMPLETED NA

Improving Asthma Care Through Parental Empowerment

NCT00832923

COMPLETED

Clinical Performance Evaluation of Pediatric and Neonatal Low Saturation Oximetry Sensors

NCT00843401

COMPLETED NA

Magnetic Resonance Imaging (MRI) of Appendicitis in Children

NCT00723788

COMPLETED Phase 3

The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart Disease

NCT00480740

COMPLETED Phase 4

Dexmedetomidine vs Fentanyl for BMT

NCT00654329

COMPLETED Phase 4

Use of Sustained Release Antiepileptic Medication (Depakote® ER) for Pediatric Epilepsy in a Mental Retardation/Developmental Disorder Population

NCT00207935

COMPLETED Phase 4

Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy

NCT00654511

TERMINATED

Optimizing Antiretroviral Therapy in HIV-Infected Children and Adolescents

NCT00207948

COMPLETED

Prevalence of Proteinuria and Chronic Kidney Disease in Pediatric HIV-Infected Patients

NCT00153621

COMPLETED Phase 3

Pharmacokinetics, Safety and Tolerability of Zavesca (Miglustat) in Patients With Infantile Onset Gangliosidosis: Single and Steady State Oral Doses

NCT00672022

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What is open in the Children's National Research Institute pipeline

35 recruiting of 92 indexed (38% open); 41 completed (45%).

Phase mix: 5 late (III/IV) vs 18 early (I/II) (early-phase heavy).

Top condition: Sickle Cell Disease (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Children's National Research Institute: open-pipeline peers nationwide

Peers matched on 92 registered trials and 38% open enrollment, not the therapeutic-area sidebar.

Children's National Research Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 020406080100 10%20%30%40% Total trials Recruiting share Children's National Research InstituteDrexel UniversityLoyola UniversityNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)National Institute on Alcohol Abuse and Alcoholism (NIAAA)Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)Intra-Cellular TherapiesMorehouse School of MedicineNortheastern University
Children's National Research Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Children's National Research Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 92 trials (± recruiting share)

Sponsors near 38% open enrollment (± trial volume)

What to do with this Children's National Research Institute page

92 registered trials is a research-attention snapshot, not an endorsement of Children's National Research Institute or any single study.

  • 35 of Children's National Research Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Sickle Cell Disease is the condition Children's National Research Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sickle Cell Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Children's National Research Institute pipeline card: 92 registered trials from official public datasets.Report a data error.