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NCT04786977 · ClinicalTrials.gov registry record
Physiologic Measure of VIPN
A clinical trial of Chemotherapy-induced Peripheral Neuropathy, sponsored by Children's National Research Institute.
- Recruiting
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT04786977 is a study of Chemotherapy-induced Peripheral Neuropathy that is actively recruiting participants, run by Children's National Research Institute. The registered enrollment target is 40 participants, below the 137-participant average among 29 other Chemotherapy-induced Peripheral Neuropathy trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04786977, a study of Chemotherapy-induced Peripheral Neuropathy, is actively recruiting participants, sponsored by Children's National Research Institute.
- RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is the development of a physiologic endpoint using a novel technology that would provide an objective, easy to use and more sensitive assessment of VIPN in children and adolescents. The ability to more easily detect and monitor VIPN, even before it is clinically evident, would facilitate optimizing the dosing of vincristine for maximal disease response while minimizing the risk of lifelong functional deficits affecting quality of life. This approach would also enable the development of specific therapies to minimize or eliminate the occurrence of VIPN in children and adolescents. This is a single site study that aims to develop a novel device to evaluate and characterize vincristine-induced neuropathic pain. The investigators will enroll patients with ALL following the Delayed Intensification (DI) phase of treatment. At each study visit, the investigators will evaluate the nPRD as well as the TNS-PV. The nPRD will inform the neuropathy index which will be used to compare to the TNS-PV. We anticipate a correlation between the two.
Conditions Studied
Interventions
- OTHER No Intervention, Observational Study
Study Locations (1)
District of Columbia
- Children's National Health System - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-09-20 |
| Est. Completion | 2025-12-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04786977
The ClinicalTrials.gov registry entry for NCT04786977 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 137-participant average among 29 other Chemotherapy-induced Peripheral Neuropathy trials with a reported enrollment target (71% lower). The listed sponsor is Children's National Research Institute, which has 92 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Chemotherapy-induced Peripheral Neuropathy appearing as the primary indexed condition, and to 1 intervention - of which No Intervention, Observational Study is the first listed.
NCT04786977 reports 1 study location spanning 1 distinct geographic area - top geographies include District of Columbia.
Frequently Asked Questions
What is clinical trial NCT04786977 about?
NCT04786977 is a clinical study titled "Physiologic Measure of VIPN". The purpose of this study is the development of a physiologic endpoint using a novel technology that would provide an objective, easy to use and more sensitive assessment of VIPN in children and adolescents. The ability to more easily detect and monitor VIPN, even before it is clinically evident, wo...
What is the current status of trial NCT04786977?
This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2021-09-20. Estimated completion is 2025-12-01.
What conditions does trial NCT04786977 study?
This clinical trial studies the following conditions: Chemotherapy-induced Peripheral Neuropathy.
What interventions are being tested in trial NCT04786977?
The interventions under investigation include: No Intervention, Observational Study (OTHER).
Who is sponsoring clinical trial NCT04786977?
This trial is sponsored by Children's National Research Institute, which has 92 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04786977 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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