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2026 data Public-data reference. official source

Pregnancy Complications

Open-data reference.

39 US clinical trials · 27 currently recruiting

Active & Recent Trials

RECRUITING 24,000 participants

Boston Birth Cohort Study

Johns Hopkins Bloomberg School of Public Health

NCT03228875

RECRUITING 2,600 participants

The Heartland Study

Heartland Health Research Alliance

NCT05492708

RECRUITING NA 1,440 participants

Delivering HOPE (Helping Women Optimize Prenatal Equity)

University of Arkansas

NCT06814509

RECRUITING 1,000 participants

Risk of Recurrent CeAD After Pregnancy

University Hospital, Basel, Switzerland

NCT06258109

RECRUITING 728 participants

Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring

Sumitomo Pharma Switzerland

NCT05739123

RECRUITING NA 500 participants

Sleep Behaviors in Pregnancy

University of Michigan

NCT04205370

RECRUITING 500 participants

Hemophilia A Research Program

University of Washington

NCT07414511

RECRUITING NA 454 participants

Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial

University of Pittsburgh

NCT05655936

RECRUITING NA 432 participants

Melanated Group Midwifery Care (MGMC)

University of Illinois at Chicago

NCT05365815

RECRUITING NA 400 participants

Food Provision in Prenatal Care

University of Arkansas

NCT06711627

RECRUITING NA 400 participants

Providing an Optimized and Empowered Pregnancy for You (POPPY) Aim 3: Randomized Controlled Trial

University of Alabama at Birmingham

NCT06510075

RECRUITING 320 participants

Prenatal Sonographic Prediction of Placental Histology and Function

Endeavor Health

NCT06022458

RECRUITING NA 216 participants

The Periviable GOALS Decision Support Tool

Indiana University

NCT05264779

RECRUITING Phase 2 150 participants

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

Cedars-Sinai Medical Center

NCT05552053

RECRUITING NA 150 participants

Better Lifestyle Counseling for African American Women During Pregnancy

University of Illinois at Chicago

NCT05234125

RECRUITING NA 124 participants

Nourishing Beginnings: Addressing Food Insecurity During Pregnancy

Case Western Reserve University

NCT05341960

RECRUITING NA 100 participants

Impact of Patient Selected Visual Art in the Hospital Room During Antepartum Admission on Hospital Satisfaction Scores and Patient Experience

Albany Medical College

NCT06790043

RECRUITING Phase 4 60 participants

Treatment With Aspirin After Preeclampsia: TAP Trial

Malamo Countouris

NCT06281665

RECRUITING 60 participants

Placental Imaging Techniques

Carilion Clinic

NCT06861309

RECRUITING Phase 2 55 participants

IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy

David Ware Branch

NCT03152058

RECRUITING 50 participants

Feasibility and Acceptability of HCV Treatment in Pregnancy

Washington University School of Medicine

NCT06367465

RECRUITING 50 participants

Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

University of Tennessee Graduate School of Medicine

NCT06802861

RECRUITING 40 participants

Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

Children's National Research Institute

NCT06026969

RECRUITING Phase 3 40 participants

Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE)

Washington University School of Medicine

NCT05790252

RECRUITING Phase 2 30 participants

Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes

Jaeb Center for Health Research

NCT06535789

RECRUITING 30 participants

Navigating Pregnancy and Parenthood With Lyme Disease

Children's National Research Institute

NCT06397794

RECRUITING 10 participants

Maternal and Postnatal Outcomes Study (MOS): A Global Observational Registry Assessing the Safety of Elfabrio® in Women With Fabry Disease and Their Infants During Pregnancy and Breastfeeding

Chiesi Farmaceutici S.p.A.

NCT06941025

ACTIVE NOT RECRUITING 530 participants

MYFEMBREE®: A Retrospective Cohort Study Using an Administrative Healthcare Database to Assess Pregnancy Outcomes in Women Treated With Relugolix Combination Therapy

Sumitomo Pharma Switzerland

NCT05739136

ACTIVE NOT RECRUITING 500 participants

ANXA5 M2 Haplotyping in IVF Patients and Embryos

Genomic Prediction

NCT04544462

COMPLETED 89,132 participants

Comparative Effectiveness of Treatment Options for Genital Herpes Infection to Reduce Adverse Pregnancy Outcomes

Kaiser Permanente

NCT02986802

COMPLETED 10,038 participants

Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT01322529

COMPLETED 6,894 participants

Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic

Pregistry

NCT04385238

COMPLETED NA 5,217 participants

An Evaluation of the Team Birth Project

Harvard School of Public Health (HSPH)

NCT03529214

COMPLETED NA 691 participants

Ensuring Patients' Informed Access to Noninvasive Prenatal Testing

The Cleveland Clinic

NCT03420274

COMPLETED Phase 3 292 participants

TIPPS: Thrombophilia in Pregnancy Prophylaxis Study

Ottawa Hospital Research Institute

NCT00967382

COMPLETED 283 participants

Cytomegalovirus (CMV) Infection in Pregnancy

University of Pennsylvania

NCT00194155

COMPLETED NA 148 participants

Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia

University of Pittsburgh

NCT03749746

COMPLETED 56 participants

NT-proBNP Levels and Obesity in Pregnancy

Duke University

NCT04049136

COMPLETED NA 51 participants

Sedentary Behavior Reduction in Pregnancy Intervention Study

University of Pittsburgh

NCT05093842

Phase Distribution

PhaseTrial count
Phase 2 3
Phase 3 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pregnancy Complications Trial Landscape

ClinicalTrials.gov lists 39 US studies indexed under Pregnancy Complications, and 27 of those are currently open to recruitment — roughly 69% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Pregnancy Complications shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Pregnancy Complications is led by University of Pittsburgh with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 39 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pregnancy Complications?

PlainTrial tracks 39 US clinical trials for Pregnancy Complications, of which 27 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pregnancy Complications?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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