Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07336264 · ClinicalTrials.gov registry record
Characterization of Acute Pain
A clinical trial of Postoperative Pain and Acute Pain, sponsored by Children's National Research Institute.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT07336264: Recruiting study of Postoperative Pain and Acute Pain, sponsored by Children's National Research Institute.
NCT07336264 is a study of Postoperative Pain and Acute Pain that is actively recruiting participants, run by Children's National Research Institute. The registered enrollment target is 100 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07336264, a study of Postoperative Pain and Acute Pain, is actively recruiting participants, sponsored by Children's National Research Institute.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to better understand how acute pain and responses to pain treatment can be measured in children and adolescents using a non-invasive device. Pain is usually assessed using self-reported or observational scales, which can be difficult to interpret, especially in pediatric patients. This study will evaluate whether a novel device, the AlgometRx Nociometer, can provide an objective measure of nociceptive pain. Participants ages 6 to 21 years who are undergoing elective surgery or bone marrow transplantation will be enrolled at Children's National Hospital. The device measures changes in pupil size in response to gentle electrical stimulation, which reflects activity in pain-related nerve pathways. Measurements will be taken before and after procedures and during routine hospital care, alongside standard pain assessments. This is an observational study. Participation will not change or guide any medical treatment, and all pain management will follow standard clinical care. The information collected may help improve future pain assessment and treatment for pediatric patients.
Primary Outcome
The nociceptive index calculated from neuroselective stimulus-induced pupillary reflex dilation (nPRD) measurements obtained using the AlgometRx Nociometer. The index is derived from the area under the curve (AUC) of pupillary dilation responses corresponding to selective activation of sensory nerve fiber types and is used to characterize acute nociceptive pain.
Conditions Studied
Interventions
- DEVICE AlgometRx Nociometer
Study Locations (1)
District of Columbia
- Children's National Hospital - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-12-02 |
| Est. Completion | 2028-06-02 |
What NCT07336264 shows while recruiting
NCT07336264 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (57% lower).
The record links to 3 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 1 intervention - of which AlgometRx Nociometer is the first listed.
NCT07336264 reports a single indexed study location in District of Columbia.
Frequently Asked Questions
What is clinical trial NCT07336264 about?
NCT07336264 is a clinical study titled "Characterization of Acute Pain". This study aims to better understand how acute pain and responses to pain treatment can be measured in children and adolescents using a non-invasive device. Pain is usually assessed using self-reported or observational scales, which can be difficult to interpret, especially in pediatric patients. Th...
What is the current status of trial NCT07336264?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2025-12-02. Estimated completion is 2028-06-02.
What conditions does trial NCT07336264 study?
This clinical trial studies the following conditions: Postoperative Pain, Acute Pain, Acute Pain, Postoperative.
What interventions are being tested in trial NCT07336264?
The interventions under investigation include: AlgometRx Nociometer (DEVICE).
Who is sponsoring clinical trial NCT07336264?
This trial is sponsored by Children's National Research Institute, which has 92 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07336264 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07336264's enrollment target sits among peer trials
100 55th of 120 higher than 59 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Study of TLC590 for Postsurgical Pain Following Bunionectomy
RECRUITING · Phase 3
-
A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain
RECRUITING · Phase 3
-
Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI
RECRUITING · Phase 2
-
Opioid Prescribing Practices in Laparoscopic Gynecologic Surgery
RECRUITING · NA
-
Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery
RECRUITING · NA
-
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
RECRUITING · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI