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NCT04196374 · ClinicalTrials.gov registry record · NA

Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts

A NA study, sponsored by Brigham and Women's Hospital.

Completed
Registry status
NA
Development phase
48
Enrollment target

NCT04196374 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 48 participants.

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The verdict

NCT04196374, a NA study, has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
NA
Development phase
48 participants
Enrollment target

Study Summary

The PopSeq Project is a prospective cohort study that will develop and implement a genomic return of results (gRoR) process in the Framingham Heart Study (FHS) and Jackson Heart Study (JHS) cohorts and explore associated medical, behavioral, and economic outcomes. The study will interpret the genomic sequences of JHS/FHS participants previously sequenced by TOPMed who have consented to genomic return of results and/or genetic testing. We will develop and apply new methods for scalable screening/ classification of genomic variants and will explore genomic penetrance by phenotyping a subset of participants in the FHS and JHS.

Interventions

  • GENETIC Genomic Sequencing

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2021-06-09
Est. Completion 2025-05-30
Phase NA

Sponsor

Brigham and Women's Hospital

937 total trials

What the Registry Record Tells You About NCT04196374

The ClinicalTrials.gov registry entry for NCT04196374 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Genomic Sequencing is the first listed.

NCT04196374 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04196374 about?

NCT04196374 is a clinical study titled "Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts". The PopSeq Project is a prospective cohort study that will develop and implement a genomic return of results (gRoR) process in the Framingham Heart Study (FHS) and Jackson Heart Study (JHS) cohorts and explore associated medical, behavioral, and economic outcomes. The study will interpret the genomi...

What is the current status of trial NCT04196374?

This trial is currently completed. It is a NA study. The enrollment target is 48 participants. The study started on 2021-06-09. Estimated completion is 2025-05-30.

What interventions are being tested in trial NCT04196374?

The interventions under investigation include: Genomic Sequencing (GENETIC).

Who is sponsoring clinical trial NCT04196374?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.