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NCT04603560 · ClinicalTrials.gov registry record · NA
Personalizing Intervention to Reduce Clinical Inertia in the Treatment of Hypertension
A NA study of Hypertension, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 511
- Enrollment target
- 1
- Study location
NCT04603560: Completed NA study of Hypertension, sponsored by Brigham and Women's Hospital.
NCT04603560 is a NA study of Hypertension that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 511 participants, below the 3,506-participant average among 470 other Hypertension trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04603560, a NA study of Hypertension, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 511 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a three-arm pragmatic randomized controlled trial to test two interventions targeting clinical inertia in hypertension compared to control, followed by predictive modeling to identify factors that are associated with intervention responsiveness. Study investigators will use EHR data to identify providers of patients whose hypertension treatment was not intensified. Primary care physicians will then be randomized to one of three arms: pharmacist e-detailing, provider dashboards, or no intervention (control). After the intervention, the investigators will conduct virtual interviews with select providers from each arm. A predictive modeling approach will then be used to identify patient and provider characteristics that are associated with inertia and with responsiveness to each intervention.
Primary Outcome
The primary outcome was whether physicians intensified treatment at the target visit. Intensification was defined as adding a new antihypertensive medication or increasing the total daily dose of an existing one. This was measured by identifying all prescriptions for anti-hypertensive medications in the electronic health record (EHR) on the day of the target visit and comparing the medication name and total daily dose to anti-hypertensive medications prescribed prior to the target visit date, fo
Conditions Studied
Interventions
- BEHAVIORAL Audit and Feedback
- BEHAVIORAL Pharmacist E-Detailing
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 511 participants |
| Start Date | 2021-10-26 |
| Est. Completion | 2023-02-08 |
| Phase | NA |
What the finished NCT04603560 record still lists
NCT04603560 is an interventional study that assigns participants to a tested intervention. The registered 511 participants enrollment target is mid-sized for trials with a published cap, below the 3,506-participant average among 470 other Hypertension trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Audit and Feedback is the first listed.
NCT04603560 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04603560 about?
NCT04603560 is a clinical study titled "Personalizing Intervention to Reduce Clinical Inertia in the Treatment of Hypertension". This is a three-arm pragmatic randomized controlled trial to test two interventions targeting clinical inertia in hypertension compared to control, followed by predictive modeling to identify factors that are associated with intervention responsiveness. Study investigators will use EHR data to ident...
What is the current status of trial NCT04603560?
This trial is currently completed. It is a NA study. The enrollment target is 511 participants. The study started on 2021-10-26. Estimated completion is 2023-02-08.
What conditions does trial NCT04603560 study?
This clinical trial studies the following conditions: Hypertension.
What interventions are being tested in trial NCT04603560?
The interventions under investigation include: Audit and Feedback (BEHAVIORAL), Pharmacist E-Detailing (BEHAVIORAL).
Who is sponsoring clinical trial NCT04603560?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04603560 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04603560's enrollment target sits among peer trials
511 115th of 470 higher than 356 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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