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NCT00818766 · ClinicalTrials.gov registry record · NA

Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy

A NA study, sponsored by Brigham and Women's Hospital.

Completed
Registry status
NA
Development phase
251
Enrollment target

NCT00818766: Completed NA study, sponsored by Brigham and Women's Hospital.

NCT00818766 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 251 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00818766, a NA study, has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
NA
Development phase
251 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate if post-operative antibiotic prophylaxis decreases infectious complications when compared to pre-operative antibiotics alone, in patients undergoing elective thoracic surgery requiring tube thoracostomy (chest tube).

Primary Outcome

Infectious complications include: surgical site infection, empyema, pneumonia, and the occurrence of Clostridium difficile colitis within 28 days of surgery. Participants are only counted once regardless of how many different infectious complications they had.

Interventions

  • DRUG Placebo
  • DRUG cefazolin or vancomycin

Trial Details

FieldValue
Enrollment Target 251 participants
Start Date 2008-03
Est. Completion 2011-04
Phase NA
Brigham and Women's Hospital

937 total trials

What the finished NCT00818766 record still lists

NCT00818766 is an interventional study that assigns participants to a tested intervention. The registered 251 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00818766 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00818766 about?

NCT00818766 is a clinical study titled "Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy". The purpose of this study is to evaluate if post-operative antibiotic prophylaxis decreases infectious complications when compared to pre-operative antibiotics alone, in patients undergoing elective thoracic surgery requiring tube thoracostomy (chest tube).

What is the current status of trial NCT00818766?

This trial is currently completed. It is a NA study. The enrollment target is 251 participants. The study started on 2008-03. Estimated completion is 2011-04.

What interventions are being tested in trial NCT00818766?

The interventions under investigation include: Placebo (DRUG), cefazolin or vancomycin (DRUG).

Who is sponsoring clinical trial NCT00818766?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00818766's enrollment target sits among peer trials

251 410th of 2000 higher than 1,591 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00818766, the US trial registry maintained by the National Library of Medicine. NCT00818766 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.