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NCT00595114 · ClinicalTrials.gov registry record
Association Between Increased Oxidative Stress, Anti-Inflammatory Fatty Acid Formation, and Airway Infection in People With Asthma and Chronic Obstructive Pulmonary Disease
A clinical trial of Asthma and Pulmonary Disease, Chronic Obstructive, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- 43
- Enrollment target
- 1
- Study location
NCT00595114: Completed study of Asthma and Pulmonary Disease, Chronic Obstructive, sponsored by Brigham and Women's Hospital.
NCT00595114 is a study of Asthma and Pulmonary Disease, Chronic Obstructive that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 43 participants, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00595114, a study of Asthma and Pulmonary Disease, Chronic Obstructive, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- 43 participants
- Enrollment target
- 1
- Study location
Study Summary
Chronic obstructive pulmonary disease (COPD) and asthma are common respiratory diseases in which people experience long-term inflammation of the lungs. Exacerbations, or prolonged worsening of symptoms, of asthma and COPD are often life-threatening and can lead to frequent need for hospitalization. Even with the proper use of bronchodilators, corticosteroids, and other currently available medications, clinical responses among people with COPD and asthma are variable. There remains a significant unmet clinical need for new therapeutic approaches and insights, including the identification of biomarkers to accurately assess the presence of airway infection and intensity of airway inflammation. This study will investigate potential natural biological causes and new biomarkers for increased susceptibility to persistent airway infection in asthma and COPD.
Primary Outcome
8-isoprostane levels in sputum
Conditions Studied
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2007-12 |
| Est. Completion | 2009-08 |
What the finished NCT00595114 record still lists
NCT00595114 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Asthma appearing as the primary indexed condition, and to 0 interventions.
NCT00595114 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00595114 about?
NCT00595114 is a clinical study titled "Association Between Increased Oxidative Stress, Anti-Inflammatory Fatty Acid Formation, and Airway Infection in People With Asthma and Chronic Obstructive Pulmonary Disease". Chronic obstructive pulmonary disease (COPD) and asthma are common respiratory diseases in which people experience long-term inflammation of the lungs. Exacerbations, or prolonged worsening of symptoms, of asthma and COPD are often life-threatening and can lead to frequent need for hospitalization. ...
What is the current status of trial NCT00595114?
This trial is currently completed. The enrollment target is 43 participants. The study started on 2007-12. Estimated completion is 2009-08.
What conditions does trial NCT00595114 study?
This clinical trial studies the following conditions: Asthma, Pulmonary Disease, Chronic Obstructive.
Who is sponsoring clinical trial NCT00595114?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00595114 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00595114's enrollment target sits among peer trials
43 277th of 374 higher than 96 of 374 other Asthma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Asthma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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