Boston Children's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Boston Children's Hospital sits in the top decile of US sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count).

462 total trials 110 currently recruiting 268 completed early-phase tilt top decile by trial count

Boston Children's Hospital: 462 sponsored US clinical trials, 110 recruiting.

Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.

Top-decile sponsor footprint

Boston Children's Hospital ranks in the top decile of sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

268 of 303 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

462 total, page 5 of 10

TERMINATED

Pharmacokinetics of Antibiotics During Extracorporeal Membrane Oxygenation (ECMO) Support

NCT03922451

COMPLETED

Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD

NCT04107701

COMPLETED NA

The Use of Music for Neonates Post-Cardiac Surgery

NCT03925584

COMPLETED Phase 3

Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: A Pilot Study

NCT03936387

COMPLETED NA

Use of an External Erectile Device in Transgender Man Following Phalloplasty

NCT03823014

COMPLETED NA

Mobile-based Social Services Screening and Referral Tool in an Pediatric Emergency Department

NCT03562910

COMPLETED

Predictors of Sepsis in Ex-Preterm Infants

NCT03433846

TERMINATED Phase 3

Continuous Erector Spinae Block Versus Continuous Paravertebral Block

NCT03768440

COMPLETED

Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale

NCT05373979

COMPLETED NA

Psychological Skills Group for Youth of Refugee and Immigrant Backgrounds

NCT03763591

COMPLETED

Association of Platelet Parameters With Bleeding Severity in Children With ITP

NCT03810352

COMPLETED Phase 4

Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease

NCT03667703

COMPLETED

Nutrition Status of Adults With PKU Before and During Treatment With Pegvaliase

NCT03856203

COMPLETED NA

Improving Therapeutic Patient Education for Atopic Dermatitis: Evaluation of a Parent Handbook

NCT03722706

COMPLETED NA

SIMDiscovery: The Benefits of Utilizing a Simulation Preparation Program for Spinal Fusion Surgery

NCT03835390

COMPLETED

Nutrition Status of Adults Treated With Pegvaliase

NCT03792451

COMPLETED NA

Developing e-Health Systems to Improve Growth and Nutrition in CF

NCT03635762

COMPLETED NA

JASPER Intervention in Down Syndrome

NCT03653143

COMPLETED NA

The Effects of a Sub-maximal Exercise Program on Adolescents Who Sustained a Concussion

NCT03170856

COMPLETED NA

The Impact of an 8-week Supported Exercise Program on Fitness and Symptoms in Adolescents With Down Syndrome

NCT03192540

COMPLETED NA

Feasibility of a Mobile Medication Plan Application in CF Patient Care

NCT03637504

COMPLETED

Effect of NPO Time and Type of Food Intake on Preoperative Residual Gastric Content and pH

NCT03448991

COMPLETED Phase 1

Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in Children

NCT03447782

COMPLETED NA

Seizure Rescue Medication: Caregiver Education in a Simulation Setting

NCT03562351

COMPLETED NA

Brief Alcohol Intervention and mHealth Booster for Suicidal Adolescents

NCT03607318

COMPLETED

Analysis of Glycemic Control in Type 1 Diabetes Patients Using Hybrid Closed Loop Insulin Pump Therapy (Medtronic 670G)

NCT04051632

COMPLETED

Boston Outcomes of Autism in Toddlers Study

NCT03517163

COMPLETED

The Effect of Fontan Fenestration Closure on Hepatic Stiffness

NCT03481985

COMPLETED

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

NCT03426059

TERMINATED NA

FB4 (Framingham, Boston, Bloomington, Birmingham, and Baylor)

NCT03394664

COMPLETED NA

Weight-based Flow Rates for Children With Bronchiolitis on High-Flow Nasal Cannula: A Pilot Randomized Control Trial

NCT03492307

TERMINATED

Pilot Study of a Non-Invasive Central Venous Pressure Monitoring System in Children

NCT03160742

TERMINATED NA

Child HCAHPS: Automated Day of Discharge Survey

NCT03441503

COMPLETED NA

Family Activation and Communication About Errors and Safety (FACES)

NCT02877017

COMPLETED NA

Offset Analgesia as a Measure of Central Sensitization in Children

NCT03445403

COMPLETED Phase 2

Pilot Study of Metformin for Patients With Fanconi Anemia

NCT03398824

COMPLETED

Outcomes of an Intraoperative Bispectral Index Monitor

NCT03052543

COMPLETED

Clinical Characteristics and Associations of the "Good Fontan" Patient

NCT03470428

COMPLETED

Environmental Assessment of Sleep in Youth

NCT03224455

COMPLETED

Pediatric International Nutrition Study 2018

NCT03223038

COMPLETED

Biokinetics Study for Tc-99m MAG3 in Pediatric Molecular Imaging

NCT03107286

TERMINATED Phase 3

A Prospective Controlled Treatment Trial for Post-Traumatic Headaches

NCT03007420

COMPLETED

The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease

NCT03073122

COMPLETED

Biokinetics Study for Tc-99m MDP in Pediatric Molecular Imaging

NCT03107247

COMPLETED

Biokinetics Study of Tc-99m DMSA in Pediatric Molecular Imaging

NCT03107195

COMPLETED

MRI Spectroscopy and Neuropsychological Functioning in Phenylketonuria

NCT03097250

TERMINATED NA

Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome

NCT03105362

COMPLETED

Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use

NCT04263662

COMPLETED

Protease Activated Receptor-2 and Gastrointestinal Dysfunction in Critical Illness

NCT03011151

COMPLETED Phase 4

Bacterial Contamination: Iodine vs Saline Irrigation in Pediatric Spine Surgery

NCT02527512

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Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 23
Phase 3 12
Phase 4 23

What is open in the Boston Children's Hospital pipeline

110 recruiting of 462 indexed (24% open); 268 completed (58%).

Phase mix: 35 late (III/IV) vs 53 early (I/II) (early-phase heavy).

Top condition: Congenital Heart Disease (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Boston Children's Hospital: open-pipeline peers nationwide

Peers matched on 462 registered trials and 24% open enrollment, not the therapeutic-area sidebar.

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share Boston Children's HospitalUniversity of VirginiaMedical College of WisconsinAlliance for Clinical Trials in OncologyFred Hutchinson Cancer CenterAdventHealth Translational Research InstituteAuburn UniversityChugai PharmaceuticalHALEON
Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 462 trials (± recruiting share)

Sponsors near 24% open enrollment (± trial volume)

What to do with this Boston Children's Hospital page

462 registered trials is a research-attention snapshot, not an endorsement of Boston Children's Hospital or any single study.

  • 110 of Boston Children's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Congenital Heart Disease is the condition Boston Children's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Congenital Heart Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Boston Children's Hospital pipeline card: 462 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.