Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03170856 · ClinicalTrials.gov registry record · NA
The Effects of a Sub-maximal Exercise Program on Adolescents Who Sustained a Concussion
A NA study of Concussion, Brain and Concussion, Mild, sponsored by Boston Children's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 41
- Enrollment target
- 1
- Study location
NCT03170856: Completed NA study of Concussion, Brain and Concussion, Mild, sponsored by Boston Children's Hospital.
NCT03170856 is a NA study of Concussion, Brain and Concussion, Mild that has completed, run by Boston Children's Hospital. The registered enrollment target is 41 participants, below the 182-participant average among 20 other Concussion, Brain trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03170856, a NA study of Concussion, Brain and Concussion, Mild, has completed, sponsored by Boston Children's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 41 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients who sustain a concussion will undergo a sub-maximal exercise protocol throughout their recovery. Cerebrovascular function, heart rate, and symptom severity, and exercise volume will be monitored throughout.
Primary Outcome
Cerebral vasoreactivity was determined by assessing cerebrovascular conductance response to incremental hypercapnia elicited by rebreathing. Participants were fitted with a mouthpiece attached to a three-way respiratory valve unit, which, in turn, was attached to a 5-L rubber rebreathing bag. The valve allowed for an instantaneous switch from room air to the rebreathing bag, which had been prefilled with room air. EtCO2 was measured continuously via a sample line connecting the mouthpiece to an
Conditions Studied
Interventions
- OTHER Sub-maximal exercise
Study Locations (1)
Massachusetts
- Spaulding Rehabilitation Hospital - Cambridge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2018-10-01 |
| Est. Completion | 2021-09-01 |
| Phase | NA |
What the finished NCT03170856 record still lists
NCT03170856 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 182-participant average among 20 other Concussion, Brain trials with a reported enrollment target (77% lower).
The record links to 4 conditions, with Concussion, Brain appearing as the primary indexed condition, and to 1 intervention - of which Sub-maximal exercise is the first listed.
NCT03170856 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03170856 about?
NCT03170856 is a clinical study titled "The Effects of a Sub-maximal Exercise Program on Adolescents Who Sustained a Concussion". Patients who sustain a concussion will undergo a sub-maximal exercise protocol throughout their recovery. Cerebrovascular function, heart rate, and symptom severity, and exercise volume will be monitored throughout.
What is the current status of trial NCT03170856?
This trial is currently completed. It is a NA study. The enrollment target is 41 participants. The study started on 2018-10-01. Estimated completion is 2021-09-01.
What conditions does trial NCT03170856 study?
This clinical trial studies the following conditions: Concussion, Brain, Concussion, Mild, Concussion, Severe, Exertion; Excess.
What interventions are being tested in trial NCT03170856?
The interventions under investigation include: Sub-maximal exercise (OTHER).
Who is sponsoring clinical trial NCT03170856?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03170856 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Concussion, Brain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03170856's enrollment target sits among peer trials
41 20th of 20 higher than 1 of 20 other Concussion, Brain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Concussion, Brain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
RECRUITING · NA
-
A Pragmatic Rehabilitation Intervention: The Active Rehab Study
RECRUITING · NA
-
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
RECRUITING · NA
-
Creatine Supplementation in Concussion Recovery
RECRUITING · NA
-
The Influence of Prescribed Exercise on Pain Related Fear Following Concussion in Collegiate Athletes
RECRUITING · NA
-
Concussion Health Improvement Program
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03449238 · 41 participants · Phase 1
Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients
- NCT03900793 · 41 participants · Phase 1
Losartan + Sunitinib in Treatment of Osteosarcoma
- NCT04082520 · 41 participants · Phase 2
Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy
- NCT04220190 · 41 participants · Phase 2
RAPA-501 Therapy for ALS
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI