Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03810352 · ClinicalTrials.gov registry record

Association of Platelet Parameters With Bleeding Severity in Children With ITP

A clinical trial, sponsored by Boston Children's Hospital.

Completed
Registry status
95
Enrollment target

NCT03810352: Completed study, sponsored by Boston Children's Hospital.

NCT03810352 is a clinical trial that has completed, run by Boston Children's Hospital. The registered enrollment target is 95 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03810352 has completed, sponsored by Boston Children's Hospital.

COMPLETED
Registry status
95 participants
Enrollment target

Study Summary

Patients with severe immune thrombocytopenia (ITP) present with similarly low platelet counts but varying bleeding symptoms, making it difficult to predict the disease course and to decide on an appropriate treatment plan. In a single-center study, platelet parameters including the immature platelet fraction, the absolute immature platelet count , and functional response markers were found to be significantly associated with patient bleeding severity, independent of platelet count. This study aims to confirm and replicate these findings in a multi-center patient population and to investigate the use of these parameters to better predict disease severity and bleeding events.

Primary Outcome

Evaluate in a multi-center study the association, independent of platelet count, of IPF measured by the Sysmex XN-1000 with concurrent, subsequent, and worst-ever bleeding in children with ITP.

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2019-03-15
Est. Completion 2023-11-26
Boston Children's Hospital

462 total trials

What the finished NCT03810352 record still lists

NCT03810352 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 95 participants, a relatively small participant target.

The record links to 0 conditions, and to 0 interventions.

NCT03810352 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03810352 about?

NCT03810352 is a clinical study titled "Association of Platelet Parameters With Bleeding Severity in Children With ITP". Patients with severe immune thrombocytopenia (ITP) present with similarly low platelet counts but varying bleeding symptoms, making it difficult to predict the disease course and to decide on an appropriate treatment plan. In a single-center study, platelet parameters including the immature platelet...

What is the current status of trial NCT03810352?

This trial is currently completed. The enrollment target is 95 participants. The study started on 2019-03-15. Estimated completion is 2023-11-26.

Who is sponsoring clinical trial NCT03810352?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03339128 · 95 participants · Phase 2

    Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

  • NCT03509961 · 95 participants · Phase 2

    The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

  • NCT03694756 · 95 participants · NA

    TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer

  • NCT04206215 · 95 participants · NA

    Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03810352, the US trial registry maintained by the National Library of Medicine. NCT03810352 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.