Boston Children's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Boston Children's Hospital sits in the top decile of US sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count).

462 total trials 110 currently recruiting 268 completed early-phase tilt top decile by trial count

Boston Children's Hospital: 462 sponsored US clinical trials, 110 recruiting.

Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.

Top-decile sponsor footprint

Boston Children's Hospital ranks in the top decile of sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

268 of 303 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

462 total, page 6 of 10

COMPLETED

Validation of a Novel Oxygen Consumption Measurement Technique in Neonates

NCT03154112

TERMINATED Phase 2

A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors

NCT02110069

COMPLETED Phase 1

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

NCT02991807

COMPLETED NA

A Tele-mental Health Intervention to Support Parents Caring for a Technology-dependent Child at Home

NCT03578289

COMPLETED NA

Group Education Curriculum for Older Teens With Type 1 Diabetes

NCT03147274

TERMINATED NA

A Trial of Thickened Feeds to Treat Gastroesophageal Reflux in Children Admitted After Choking Spell

NCT03130543

COMPLETED NA

Effects of Web-Based Health Information on Risk Behavior for Youth With Type 1 Diabetes in College

NCT02883829

COMPLETED NA

Trial of a Novel Brief Intervention on Health Behaviors for Youth With Chronic Medical Conditions

NCT02803567

TERMINATED

Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk

NCT03246243

COMPLETED NA

Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study

NCT03023644

COMPLETED

The Evaluation of a Noninvasive Respiratory Monitor in Intubated Infants

NCT02899351

COMPLETED NA

Variability of Infant LP Insertion Site Based On Procedural Experience

NCT02949869

COMPLETED

Analytic, Prospective Cohort Study of Athletes Enrolled in an Exercise Training Intervention

NCT02999139

COMPLETED

Innovative Approaches to Assessment of Pain Control and Sedation in the NICU

NCT03057782

COMPLETED NA

Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia

NCT02703090

COMPLETED

Validation of the Hospital Asthma Severity Score (HASS)

NCT02782065

COMPLETED

Type One Diabetes and Low Carb Study

NCT02839174

COMPLETED NA

Dietary Glycemic Index, Brain Function and Food Intake in Patients With Type 1 Diabetes Mellitus

NCT02772783

COMPLETED NA

Premie Pouch to Manage Deformational Plagiocephaly in Very Low Birth Weight Infants

NCT03184441

COMPLETED NA

Improving Neurodevelopment in Adolescents With Congenital Heart Disease

NCT02759263

COMPLETED NA

Preserved Umbilical Vein Use as Autologous Shunt Conduits in Neonatal Cardiac Surgery

NCT02766998

COMPLETED Phase 2

Dopamine Receptor Agonist Therapy for Pain Relief in Women Suffering From Endometriosis: A Pilot Study

NCT02542410

COMPLETED NA

Use of a Vibrotactile Balance Belt System for Vestibular Rehabilitation in the Pediatric Population

NCT02722486

COMPLETED NA

Community Empowerment to Pilot a Novel Device for Monitoring Rescue Medication Use in Urban Children With Asthma

NCT02517047

COMPLETED

Remote Use of the Asthma Control Test (ACT) to Improve Care of Children With Asthma

NCT03036982

COMPLETED NA

Evaluation of Electrocardiographic Guidance in Accurate Peripherally Inserted Central Catheter Placement in Children.

NCT02324504

COMPLETED

Validating Adolescent SBIRT Measures

NCT02981849

COMPLETED

Association of Transcutaneous Pulse CO-oximetry With Inflammatory Lung Diseases

NCT02831348

TERMINATED

C Tracker, Hepatitis C, Care & Collaboration - Patient Reported Outcomes Survey Study

NCT02568540

COMPLETED

Fontan Imaging Biomarkers (FIB) Study

NCT03119090

COMPLETED

The Effects of Head Trauma on Collegiate Athletes

NCT02354469

COMPLETED NA

A Prospective Study Investigating the Use of Relaxation Prior to Medical Procedures.

NCT02690194

COMPLETED NA

Adjusting Insulin Delivery to Activity

NCT02299479

COMPLETED

Examination of Balance, Vestibular, and Ocular Functions and Activity Following Concussion

NCT02317107

COMPLETED NA

Randomized Controlled Trial of an Eczema Care Plan

NCT02251340

COMPLETED

Creation, Implementation, and Analysis of a Seizure Action Plan

NCT02995759

COMPLETED

TMS for the Investigation of Brain Plasticity in Autism Spectrum Disorders

NCT02836405

COMPLETED

Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis

NCT02352675

COMPLETED

Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery

NCT02410473

COMPLETED

The Brain and Neuropsychological Functioning in Adults With Sapropterin Dihydrochloride Treated Phenylketonuria

NCT02297347

COMPLETED

The Evaluation of a Noninvasive Respiratory Monitor in Pediatric Patients Undergoing General Anesthesia

NCT02336022

COMPLETED

Platelet Function in Patients With Hemophilia A

NCT02093065

COMPLETED NA

Gaming for Autism to Mold Executive Skills Project

NCT02361762

TERMINATED NA

Efficacy of Continuous Glucose Monitoring in Neonates With Hypoglycemia

NCT02300285

COMPLETED NA

Computerized Alcohol Screening for Children and Adolescents (cASCA) in Primary Care

NCT02233946

COMPLETED NA

School Inner-City Asthma Intervention Study (SICAS-2)

NCT02291302

COMPLETED NA

Bringing I-PASS to the Bedside: A Communication Bundle to Improve Patient Safety and Experience

NCT02320175

COMPLETED NA

Using an Online Patient Monitoring System to Improve Care for Children With Chronic Conditions

NCT02097355

COMPLETED

The Determination of the Effect of Volatile Anesthetics on Leukocyte Function ex Vivo

NCT02207842

COMPLETED

Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography

NCT02247700

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Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 23
Phase 3 12
Phase 4 23

What is open in the Boston Children's Hospital pipeline

110 recruiting of 462 indexed (24% open); 268 completed (58%).

Phase mix: 35 late (III/IV) vs 53 early (I/II) (early-phase heavy).

Top condition: Congenital Heart Disease (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Boston Children's Hospital: open-pipeline peers nationwide

Peers matched on 462 registered trials and 24% open enrollment, not the therapeutic-area sidebar.

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share Boston Children's HospitalUniversity of VirginiaMedical College of WisconsinAlliance for Clinical Trials in OncologyFred Hutchinson Cancer CenterAdventHealth Translational Research InstituteAuburn UniversityChugai PharmaceuticalHALEON
Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 462 trials (± recruiting share)

Sponsors near 24% open enrollment (± trial volume)

What to do with this Boston Children's Hospital page

462 registered trials is a research-attention snapshot, not an endorsement of Boston Children's Hospital or any single study.

  • 110 of Boston Children's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Congenital Heart Disease is the condition Boston Children's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Congenital Heart Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Boston Children's Hospital pipeline card: 462 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.