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NCT04263662 · ClinicalTrials.gov registry record
Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use
A clinical trial of Mechanical Ventilation and Sedation, sponsored by Boston Children's Hospital.
- Completed
- Registry status
- 680
- Enrollment target
- 1
- Study location
NCT04263662: Completed study of Mechanical Ventilation and Sedation, sponsored by Boston Children's Hospital.
NCT04263662 is a study of Mechanical Ventilation and Sedation that has completed, run by Boston Children's Hospital. The registered enrollment target is 680 participants, above the 549-participant average among 14 other Mechanical Ventilation trials with a reported enrollment target (24% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04263662, a study of Mechanical Ventilation and Sedation, has completed, sponsored by Boston Children's Hospital.
- COMPLETED
- Registry status
- 680 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to develop and implement an evidence-based analgesia-sedation algorithm in the pediatric intensive care unit (PICU) using quality improvement and implementation science methodology. The analgesia-sedation protocol will be implemented for patients admitted to the pediatric ICU who require mechanical ventilation for greater than 24 hours. Specifically, we will examine the impact of this implementation on total benzodiazepine usage, ICU length of stay, and ventilator free days, using a pre- and post- algorithm implementation comparative design.
Primary Outcome
Total exposure of benzodiazepines (midazolam, lorazepam, diazepam) measured per kilogram of weight over the patient's duration of ICU stay.
Conditions Studied
Interventions
- OTHER Analgesia-Sedation algorithm
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 680 participants |
| Start Date | 2017-08-01 |
| Est. Completion | 2020-03-01 |
What the finished NCT04263662 record still lists
NCT04263662 is an observational study that tracks outcomes without assigning an intervention. The registered 680 participants enrollment target is mid-sized for trials with a published cap, above the 549-participant average among 14 other Mechanical Ventilation trials with a reported enrollment target (24% higher).
The record links to 2 conditions, with Mechanical Ventilation appearing as the primary indexed condition, and to 1 intervention - of which Analgesia-Sedation algorithm is the first listed.
NCT04263662 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04263662 about?
NCT04263662 is a clinical study titled "Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use". The purpose of the study is to develop and implement an evidence-based analgesia-sedation algorithm in the pediatric intensive care unit (PICU) using quality improvement and implementation science methodology. The analgesia-sedation protocol will be implemented for patients admitted to the pediatric...
What is the current status of trial NCT04263662?
This trial is currently completed. The enrollment target is 680 participants. The study started on 2017-08-01. Estimated completion is 2020-03-01.
What conditions does trial NCT04263662 study?
This clinical trial studies the following conditions: Mechanical Ventilation, Sedation.
What interventions are being tested in trial NCT04263662?
The interventions under investigation include: Analgesia-Sedation algorithm (OTHER).
Who is sponsoring clinical trial NCT04263662?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04263662 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Mechanical Ventilation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04263662's enrollment target sits among peer trials
680 4th of 14 higher than 11 of 14 other Mechanical Ventilation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mechanical Ventilation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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