Biogen

334 total trials 21 currently recruiting 237 completed

Biogen sponsors 334 registered US clinical trials on ClinicalTrials.gov, 21 of them currently recruiting, and 237 completed. 84 of these trials are in Phase 3-4 (later-stage) and 198 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Multiple Sclerosis, with 13 trials.

Trial Pipeline

334 total, page 4 of 7

TERMINATED Phase 2

A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA).

NCT02462759

TERMINATED Phase 3

221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease

NCT02477800

COMPLETED Phase 3

Effect of BG00012 on Lymphocyte Subsets and Immunoglobulins in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS).

NCT02525874

COMPLETED Phase 1

Single-Ascending Dose Study of BIIB054 in Healthy Participants and Early Parkinson's Disease

NCT02459886

COMPLETED

Tecfidera Lymphocyte Chart Review

NCT02519413

COMPLETED Phase 1

Single-Dose Study of a New Formulation of BIIB061

NCT02521545

COMPLETED Phase 1

Safety, Tolerability and Pharmacokinetics of BIIB118 (PF-05251749)

NCT02443740

COMPLETED Phase 2

A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

NCT02386553

COMPLETED Phase 2

RTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTOR

NCT02255422

TERMINATED Phase 3

BG00012 and Delay of Disability Progression in Secondary Progressive Multiple Sclerosis

NCT02430532

TERMINATED Phase 3

Tecfidera Slow-Titration Study

NCT02428231

COMPLETED

A Longitudinal, Observational Biomarker Study in Participants With Primary Sjogren's Syndrome

NCT02422407

COMPLETED Phase 4

Study of Montelukast on Gastrointestinal Tolerability in Patients With Relapsing Forms of Multiple Sclerosis Receiving Tecfidera

NCT02410278

COMPLETED Phase 2

Vaccination Response in Tecfidera-Treated Versus Interferon-Treated Participants With Relapsing Forms of Multiple Sclerosis.

NCT02097849

TERMINATED Phase 4

Study to Evaluate Whether a Medication Event Monitoring System (MEMS) Can Improve Adherence to Tecfidera Treatment in Multiple Sclerosis Patients.

NCT02343159

COMPLETED Phase 1

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of PF-04958242 in Healthy Subjects

NCT02341482

COMPLETED Phase 2

A Study to Learn About the Effects and Safety of RTA 408 (Omaveloxolone) in People Aged 16 to 40 With Friedreich's Ataxia

NCT02255435

COMPLETED Phase 1

Multiple Ascending Doses of PF-04958242 in Subjects With Stable Schizophrenia

NCT02332798

COMPLETED Phase 1

A Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study of Intravenously Administered BMS-986168 in Healthy Subjects

NCT02294851

TERMINATED Phase 4

Impact of Natalizumab Versus Fingolimod in Relapsing-Remitting Multiple Sclerosis (RRMS) Participants

NCT02342704

COMPLETED Phase 3

A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA)

NCT02292537

COMPLETED

Plegridy Observational Program

NCT02230969

COMPLETED

Observational Study to Establish Patient-Matched Population Norms for the Multiple Sclerosis Cognition Assessment Battery

NCT02283918

COMPLETED Phase 1

RTA 408 Capsules in Patients With Melanoma - REVEAL

NCT02259231

COMPLETED Phase 1

Study to Evaluate the Pharmacokinetic Profiles of BIIB017 (Peginterferon Beta-1a) and Rebif® (Interferon Beta-1a) in Healthy Volunteers

NCT02269930

TERMINATED Phase 4

Natalizumab as an Efficacy Switch in Participants With Relapsing Multiple Sclerosis After Failure on Other Therapies

NCT02241785

COMPLETED Phase 1

Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Doses Of PF-04958242 In Healthy Volunteers

NCT02228395

COMPLETED Phase 3

Efficacy and Safety Study of Prolonged-Release Fampridine in Participants With Multiple Sclerosis

NCT02219932

COMPLETED Phase 3

Phase 3 Efficacy and Safety Study of BG00012 in Pediatric Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)

NCT02283853

TERMINATED Phase 3

A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy

NCT02193074

COMPLETED Phase 1

Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB061 in Healthy Adult Volunteers

NCT02228707

COMPLETED Phase 1

A Study of ALKS 8700, a Monomethyl Fumarate (MMF) Molecule, in Healthy Adults

NCT02201849

COMPLETED

Real-world Outcomes on Tecfidera (BG00012, Dimethyl Fumarate) Post-Tysabri (BG00002, Natalizumab)

NCT02159573

COMPLETED Phase 2

RTA 408 Lotion in Patients at Risk for Radiation Dermatitis - PRIMROSE

NCT02142959

COMPLETED Phase 1

A Healthy Volunteer Study to Establish the Bioequivalence of BG00012 Supplied by 2 Different Commercial Manufacturers

NCT02171208

COMPLETED Phase 2

RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD

NCT02128113

COMPLETED Phase 2

Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT

NCT02036970

COMPLETED

Pilot Tape Harvesting Study

NCT02125695

COMPLETED Phase 1

Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Single Doses and Multiple Doses of BIIB059 (Litifilimab) in Healthy Volunteers and Participants With Systemic Lupus Erythematosus

NCT02106897

COMPLETED Phase 2

RTA 408 Ophthalmic Suspension for the Treatment of Ocular Inflammation and Pain Following Ocular Surgery

NCT02065375

COMPLETED Phase 1

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246)

NCT02052791

COMPLETED Phase 2

Effect of Natalizumab on Infarct Volume in Acute Ischemic Stroke

NCT01955707

COMPLETED Phase 1

RTA 408 Lotion in Healthy Volunteers

NCT02029716

COMPLETED Phase 1

RTA 408 in the Treatment of Advanced Solid Tumors (NSCLC & Melanoma) - DISCOVER

NCT02029729

COMPLETED Phase 1

Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB061 in Healthy Adult Volunteers Including Absolute Bioavailability and Food Effect

NCT02071121

COMPLETED

Dimethyl Fumarate (DMF) Observational Study

NCT02047097

COMPLETED Phase 3

Characterize Flu-like Symptoms in Relapsing Multiple Sclerosis Patients Transitioning From Non-Pegylated Interferon Beta (IFN-β) Therapies to Peginterferon Beta-1a (BIIB017)

NCT01939002

TERMINATED Phase 2

BIIB023 Long-Term Extension Study in Subjects With Lupus Nephritis

NCT01930890

COMPLETED

Biogen Multiple Sclerosis Pregnancy Exposure Registry

NCT01911767

COMPLETED Phase 1

A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers

NCT01943513

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What the Pipeline for Biogen Shows

According to the ClinicalTrials.gov registry, Biogen is linked to 334 US clinical trials across every stage of research activity. Of those, 21 studies are currently recruiting, about 6% of the sponsor's indexed portfolio, and 237 are already marked complete, representing roughly 71% of the total.

The phase mix for Biogen reports 84 late-stage studies (Phase 3 and Phase 4 combined) and 198 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Biogen is Multiple Sclerosis with 13 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.