Biogen

334 total trials 21 currently recruiting 237 completed

Biogen sponsors 334 registered US clinical trials on ClinicalTrials.gov, 21 of them currently recruiting, and 237 completed. 84 of these trials are in Phase 3-4 (later-stage) and 198 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Multiple Sclerosis, with 13 trials.

Trial Pipeline

334 total, page 5 of 7

COMPLETED Phase 2

Study to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of BIIB033 in Participants With Relapsing Forms of Multiple Sclerosis When Used Concurrently With Avonex

NCT01864148

COMPLETED Phase 1

PeptoBismol® Use to Reduce Gastrointestinal Events in Healthy Volunteers Receiving DMF [Tecfidera®] Twice Daily

NCT01915901

COMPLETED

Effectiveness of DMF and Its Impact on PROs in Suboptimal GA Responders With RMS

NCT01903291

COMPLETED Phase 2

BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy

NCT01873404

COMPLETED

Functional MRI in Lupus Nephritis

NCT01731054

COMPLETED Phase 2

A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (SMA)

NCT01839656

COMPLETED Phase 4

Phase 4 Gastrointestinal Tolerability Study of Dimethyl Fumarate in Patients With Relapsing Forms of Multiple Sclerosis in the United States

NCT01873417

TERMINATED Phase 3

Long-Term Extension Study in Participants With Multiple Sclerosis Who Have Completed Study 205MS301 (NCT01064401) to Evaluate the Safety and Efficacy of BIIB019

NCT01797965

COMPLETED Phase 1

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701)

NCT01780246

COMPLETED Phase 1

A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers

NCT01749098

COMPLETED Phase 1

An Open-label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy

NCT01703988

TERMINATED Phase 1

Multiple Dose Study of Aducanumab (BIIB037) (Recombinant, Fully Human Anti-Aβ IgG1 mAb) in Participants With Prodromal or Mild Alzheimer's Disease

NCT01677572

COMPLETED Phase 1

Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers

NCT01689116

COMPLETED Phase 2

STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

NCT01371305

COMPLETED Phase 1

Study in Healthy Volunteers to Establish the Bioequivalence of Two Different Manufacturers.

NCT01632449

COMPLETED Phase 1

Study Of The PF-04958242 Blood Concentrations Of A Capsule Formulation Of PF-04958242 Compared To A Solution Formulation

NCT01646840

TERMINATED Phase 2

BIIB023 Proof-of-Concept Study in Participants With Lupus Nephritis

NCT01499355

COMPLETED Phase 1

An Open-Label Study of the Effect of Bardoxolone Methyl on the Single Dose Pharmacokinetics of Digoxin and Rosuvastatin in Healthy Volunteers

NCT01598363

COMPLETED Phase 1

Peginterferon Beta-1a (BIIB017) Autoinjector Pharmacokinetic Study in Healthy Volunteers

NCT01610310

COMPLETED Phase 1

Single-Dose, Open-Label Pharmacokinetic Study of Bardoxolone Methyl in Subjects With Mild, Moderate, and Severe Hepatic Impairment and Normal Hepatic Function

NCT01563562

COMPLETED Phase 3

Effect of Aspirin Pretreatment or Slow Dose Titration on Flushing and Gastrointestinal Events in Healthy Volunteers Receiving Delayed-release Dimethyl Fumarate

NCT01568112

COMPLETED

Observational Study of Tysabri in Early Relapsing-Remitting Multiple Sclerosis in Anti-JC Virus Antibody Negative Participants

NCT01485003

COMPLETED Phase 1

Demonstrate the Bioequivalence of Interferon Beta-1a (INFB) Manufactured by Two Different Processes in Healthy Volunteers

NCT01500408

COMPLETED Phase 1

A Phase I Study to Investigate the Absorption, Metabolism and Excretion in Healthy Male Subjects

NCT01503866

COMPLETED Phase 1

A Study Of The Effects Of PF-04958242 In Subjects With Age-Related Hearing Loss

NCT01518920

COMPLETED Phase 1

An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA)

NCT01494701

COMPLETED Phase 3

An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis

NCT01462318

COMPLETED Phase 1

A Study To Examine The Safety, Tolerability And Pharmacokinetics Of PF-04958242 In Psychiatrically Stable Subjects With Schizophrenia

NCT01518894

COMPLETED Phase 1

A Single-Dose, Open-Label, Randomized, Food Effect and Blinded, Randomized, Dose Proportionality Study in Healthy Volunteers With Bardoxolone Methyl

NCT01461161

TERMINATED Phase 3

A Clinical Study of the Efficacy of Natalizumab on Reducing Disability Progression in Participants With Secondary Progressive Multiple Sclerosis

NCT01416181

COMPLETED Phase 1

Study in Healthy Volunteers to Establish the BioEquivalence of Two Formulations of BG00012

NCT01420458

COMPLETED Phase 1

A Study To Assess Effects Of PF-04958242 On Bold Functional Magnetic Resonance Imaging During Working Memory Activation And Arterial Spin Labeling At Rest In Healthy Subjects

NCT01365338

COMPLETED Phase 1

Single Ascending Dose Study of BIIB037 in Participants With Alzheimer's Disease

NCT01397539

COMPLETED Phase 1

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Repeated Doses of PF-04958242 in Healthy Volunteers

NCT01511510

COMPLETED Phase 3

Long-Term Safety and Efficacy Study of Peginterferon Beta-1a

NCT01332019

COMPLETED Phase 1

Alternate Dosing Regimens of BG00012 in Healthy Volunteers

NCT01281111

COMPLETED Phase 1

Safety Study of BIIB033 in Subjects With Multiple Sclerosis

NCT01244139

TERMINATED

Genetic Evaluation of Natalizumab-Treated Patients With Progressive Multifocal Leukoencephalopathy

NCT01211639

TERMINATED Phase 4

Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS)

NCT01211665

COMPLETED Phase 2

BG00012 Phase 2 Combination Study in Participants With Multiple Sclerosis

NCT01156311

COMPLETED

Biomarkers of Anti-TNF-α Therapy Efficacy in Rheumatoid Arthritis to Define Unresponsive Patients

NCT01211678

TERMINATED

Controlled High Risk AVONEX® Multiple Sclerosis Prevention Study In Ongoing Neurological Surveillance

NCT01156298

COMPLETED Phase 1

A Study of Avonex to Determine the Effects of Dose Titration on the Incidence of Flu Like Symptoms in Healthy Volunteers

NCT01119677

COMPLETED Phase 3

Efficacy and Safety of BIIB019 (Daclizumab High Yield Process) Versus Interferon β 1a in Participants With Relapsing-Remitting Multiple Sclerosis

NCT01064401

COMPLETED

JC Virus Antibody Study of Participants With Relapsing Forms of MS Receiving Treatment With Natalizumab

NCT01070836

COMPLETED

JC-Virus (JCV) Antibody Program

NCT01070823

COMPLETED Phase 2

Treatment Interruption of Natalizumab

NCT01071083

TERMINATED Phase 3

Study Evaluating Rebif, Copaxone, and Tysabri for Active Multiple Sclerosis

NCT01058005

COMPLETED Phase 2

Phase II Pharmacodynamic Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease

NCT01053936

COMPLETED Phase 1

Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers

NCT01132703

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What the Pipeline for Biogen Shows

According to the ClinicalTrials.gov registry, Biogen is linked to 334 US clinical trials across every stage of research activity. Of those, 21 studies are currently recruiting, about 6% of the sponsor's indexed portfolio, and 237 are already marked complete, representing roughly 71% of the total.

The phase mix for Biogen reports 84 late-stage studies (Phase 3 and Phase 4 combined) and 198 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Biogen is Multiple Sclerosis with 13 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.