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NCT02341482 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of PF-04958242 in Healthy Subjects
A Phase 1 study, sponsored by Biogen.
- Completed
- Registry status
- Phase 1
- Development phase
- 13
- Enrollment target
NCT02341482: Completed Phase 1 study, sponsored by Biogen.
NCT02341482 is a Phase 1 study that has completed, run by Biogen. The registered enrollment target is 13 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02341482, a Phase 1 study, has completed, sponsored by Biogen.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 13 participants
- Enrollment target
Study Summary
The purpose of the current study is to characterize the pharmacokinetic (PK) profile of PF 04958242 when co administered with a strong cytochrome P450 3A4 (CYP3A4) inhibitor.
Primary Outcome
AUCtau = area under the concentration-time profile from time 0 to time tau, the dosing interval, where tau = 12 hours. Collected at Day 3 for PF-04958242 0.025 mg Arm and Day 17 for PF-04958242 0.025 mg + itraconazole 200 mg Arm.
Interventions
- DRUG Itraconazole
- DRUG PF-04958242
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2015-02-05 |
| Est. Completion | 2015-03-31 |
| Phase | Phase 1 |
What the finished NCT02341482 record still lists
NCT02341482 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 2 interventions - of which Itraconazole is the first listed.
NCT02341482 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02341482 about?
NCT02341482 is a clinical study titled "A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of PF-04958242 in Healthy Subjects". The purpose of the current study is to characterize the pharmacokinetic (PK) profile of PF 04958242 when co administered with a strong cytochrome P450 3A4 (CYP3A4) inhibitor.
What is the current status of trial NCT02341482?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2015-02-05. Estimated completion is 2015-03-31.
What interventions are being tested in trial NCT02341482?
The interventions under investigation include: Itraconazole (DRUG), PF-04958242 (DRUG).
Who is sponsoring clinical trial NCT02341482?
This trial is sponsored by Biogen, which has 334 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02341482's enrollment target sits among peer trials
13 1847th of 2000 higher than 149 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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