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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Friedreich Ataxia: early-phase trial registry

7 of 15 indexed Friedreich Ataxia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 7 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Friedreich Ataxia: 15 US clinical trials tracked, 7 recruiting.

Friedreich Ataxia is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Biogen, running 4 of these trials.

Enrollment posture brief

Registry condition friedreich-ataxia

OPEN 7 | RECR 47% | LATE 2 | EARLY 5 | RANK #1140 | SPON 4

Nearest open-share peer: Autism (47% recruiting · 105 trials)

Advanced Lung Non-Small Cell53.3%Friedreich Ataxia (this)47%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Friedreich Ataxia

Friedreich Ataxia lists 7 open slots (47% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Friedreich Ataxia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Friedreich Ataxia recruits in line with its size-band peers.

    7 of 15 indexed trials (46.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Friedreich Ataxia research.

    Biogen accounts for 4 of 15 trials (26.7%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Friedreich Ataxia trials plan to enrol fewer than 100 people.

    Median target enrolment is 65 among the 15 trials that report a genuine target (sentinel values excluded). 9 of those (60%) plan for fewer than 100 participants.

  4. Friedreich Ataxia splits between interventional and observational designs.

    7 interventional and 8 observational studies make up this index (46.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 21Phase 32

Open and recent trials

15 total, page 1 of 1

RECRUITING 3,000 participants

Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

Friedreich's Ataxia Research Alliance

NCT06016946

RECRUITING 300 participants

A Study to Learn More About the Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Who Are Prescribed it by Their Own Doctors

Biogen

NCT06623890

RECRUITING Phase 3 255 participants

A Study to Learn More About the Effects and Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Aged 2 to 15 Years Old (BRAVE)

Biogen

NCT06953583

RECRUITING 65 participants

Clinical Course Of Disease In Participants With FA-CM

Lexeo Therapeutics

NCT06865482

RECRUITING Phase 1 35 participants

A Study to Find Out How BIIB141 (Omaveloxolone) is Processed in the Body and to Learn More About Its Safety in Participants With Friedreich's Ataxia Aged 2 to 15 Years Old

Biogen

NCT06054893

RECRUITING Phase 1 25 participants

Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia

Weill Medical College of Cornell University

NCT05302271

RECRUITING 20 participants

A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies

Biogen

NCT06628687

ACTIVE NOT RECRUITING 2,000 participants

FA Clinical Outcome Measures

Friedreich's Ataxia Research Alliance

NCT03090789

ACTIVE NOT RECRUITING 300 participants

A Natural History Study to TRACK Brain and Spinal Cord Changes in Individuals with Friedreich Ataxia (TRACK-FA)

Monash University

NCT04349514

ACTIVE NOT RECRUITING Phase 3 130 participants

A Study to Assess the Safety and Efficacy of Vatiquinone in Participants With Friedreich Ataxia

PTC Therapeutics

NCT05515536

ACTIVE NOT RECRUITING Phase 1 8 participants

Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia

Lexeo Therapeutics

NCT05445323

COMPLETED 85 participants

Early and Longitudinal Assessment of Neurodegeneration in the Brain and Spinal Cord in Friedreich's Ataxia

University of Minnesota

NCT01776164

COMPLETED Phase 1 32 participants

Study to Evaluate Multiple Ascending Dose and Multi-Dose of DT-216 in Adult Patients With Friedreich Ataxia

Design Therapeutics

NCT05573698

COMPLETED Phase 2 28 participants

A Double-Blind, Placebo-Controlled, Dose Exploration Study of CTI-1601 in Adult Subjects With Friedreich's Ataxia

Larimar Therapeutics

NCT05579691

COMPLETED 10 participants

Measurement of Frataxin mRNA in Biofluids

University of Florida

NCT06496451

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 1
Phase 3 2

Named interventions

Most-linked intervention names on Friedreich Ataxia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Omaveloxolone Drug
4 trials
Placebo Drug
2 trials
DT-216 Drug
1 trials
CTI-1601 Biological
1 trials
Venipuncture for blood sample Other
1 trials
Spinal tap for CSF collection Other
1 trials
Vatiquinone Drug
1 trials
High Dose LX2006 Genetic
1 trials

US sites by state

Facility locations filed on Friedreich Ataxia trials. A trial with sites in several states counts in each.

Florida 9 trials
Pennsylvania 7 trials
California 7 trials
Tennessee 3 trials
Ohio 3 trials
Minnesota 3 trials
Iowa 3 trials
Colorado 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Friedreich Ataxia page

15 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 Friedreich Ataxia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Biogen sponsors the most Friedreich Ataxia trials on record, review their full trial history before evaluating a specific study. See Biogen's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Friedreich Ataxia condition card totals 15 registered trials; most-linked intervention Omaveloxolone; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.