Biogen

334 total trials 21 currently recruiting 237 completed

Biogen sponsors 334 registered US clinical trials on ClinicalTrials.gov, 21 of them currently recruiting, and 237 completed. 84 of these trials are in Phase 3-4 (later-stage) and 198 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Multiple Sclerosis, with 13 trials.

Trial Pipeline

334 total, page 3 of 7

COMPLETED Phase 2

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy

NCT03283371

COMPLETED

Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)

NCT03088956

TERMINATED Phase 2

Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease

NCT03318523

COMPLETED Phase 2

A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX

NCT03366337

COMPLETED

MS PATHS Normative Sub-Study

NCT02996084

COMPLETED Phase 3

Efficacy and Safety of BIIB111 for the Treatment of Choroideremia

NCT03496012

COMPLETED Phase 2

A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111

NCT03507686

TERMINATED Phase 2

Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS)

NCT03222973

COMPLETED Phase 1

A Drug Interaction Study of BIIB074 and an Oral Contraceptive Regimen

NCT03324685

COMPLETED Phase 1

Effect of Itraconazole on the Pharmacokinetics of Bardoxolone Methyl in Healthy Adults

NCT03264079

COMPLETED Phase 1

Safety, Tolerability, and Pharmacokinetics of Single Doses of BIIB059 in Healthy Japanese Subjects.

NCT03224793

COMPLETED Phase 1

A Study to Assess the Pharmacodynamic Effects of SAGE-217 in Healthy Adults Using an Insomnia Model

NCT03284931

COMPLETED Phase 1

Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074

NCT03385525

COMPLETED

Tysabri Observational Cohort Study - Multiple Sclerosis (MS) Registries

NCT03399981

TERMINATED Phase 2

Study of BIIB092 in Participants With Progressive Supranuclear Palsy

NCT03068468

TERMINATED Phase 3

Efficacy and Safety of Daclizumab in Participants With RRMS Switching From Natalizumab

NCT02881567

TERMINATED Phase 3

Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER

NCT03068130

COMPLETED Phase 2

A Study to Evaluate SAGE-217 in Participants With Essential Tremor

NCT02978781

COMPLETED Phase 3

A Tolerability Study of ALKS 8700 in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS) EVOLVE-MS-2

NCT03093324

COMPLETED Phase 1

A Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using BIIB112

NCT03116113

COMPLETED Phase 3

Long-Term Evaluation of BIIB067 (Tofersen)

NCT03070119

COMPLETED Phase 2

A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL

NCT03019185

COMPLETED Phase 1

Single-Ascending-Dose Study of BIIB076 in Healthy Volunteers and Participants With Alzheimer's Disease

NCT03056729

COMPLETED

Scan-Rescan Sub-Study of MS PATHS

NCT04123353

COMPLETED Phase 3

A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression

NCT02978326

COMPLETED Phase 1

A Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of RTA 901 in Healthy Adults

NCT02666963

COMPLETED Phase 2

A Study to Evaluate SAGE-217 in Participants With Moderate to Severe Major Depressive Disorder

NCT03000530

COMPLETED Phase 1

New Formulation and Food Effect Study of BIIB074

NCT02951221

COMPLETED Phase 2

A Study to Evaluate SAGE-217 in Participants With Parkinson's Disease

NCT03000569

COMPLETED Phase 2

Study to Evaluate BIIB059 (Litifilimab) in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)

NCT02847598

TERMINATED Phase 3

Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST

NCT02657356

COMPLETED Phase 2

A Phase 2a Study of BIIB074 in the Treatment of Erythromelalgia

NCT02917187

TERMINATED Phase 2

A Study To Evaluate The Safety And Efficacy Of PF-04958242 In Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS)

NCT02855411

COMPLETED Phase 1

A Phase 1, Single-Ascending-Dose, Safety, Tolerability, Pharmacokinetic(PK), and Pharmacodynamic(PD) Study of BIIB068 in Healthy Participants

NCT02829541

COMPLETED Phase 2

Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke

NCT02730455

COMPLETED Phase 1

Pharmacokinetics, Safety and Tolerability of Single Doses of BIIB033 (Opicinumab) Produced by 2 Manufacturing Processes

NCT02833142

COMPLETED Phase 1

Absolute Bioavailability of a Single, Fixed Subcutaneous Dose of Aducanumab in Healthy Participants

NCT02782975

COMPLETED

Observational Study to Characterize Real-world Clinical Outcomes With Relapsing-remitting Multiple Sclerosis (RRMS)

NCT02776072

COMPLETED Phase 1

Absorption, Metabolism, and Excretion Study of BIIB074

NCT02751905

COMPLETED Phase 1

Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers

NCT02691702

COMPLETED

MSPT Device Usability Study

NCT02664324

COMPLETED Phase 3

Extension Study of BG00012 in Pediatric Subjects With Relapsing Remitting Multiple Sclerosis (RRMS)

NCT02555215

TERMINATED Phase 1

Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003

NCT02658916

COMPLETED Phase 3

An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 (Tofersen) in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS)

NCT02623699

COMPLETED

Methodology Study of Novel Outcome Measures to Assess Progression of ALS

NCT02611674

COMPLETED Phase 3

A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS) EVOLVE-MS-1

NCT02634307

COMPLETED Phase 3

A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies

NCT02594124

COMPLETED Phase 1

Multiple Ascending Dose Study of Intravenously Administered BMS-986168 (BIIB092) in Patients With Progressive Supranuclear Palsy

NCT02460094

COMPLETED Phase 2

Study of the Effect of BG00012 on MRI Lesions and Pharmacokinetics in Pediatric Subjects With RRMS

NCT02410200

TERMINATED Phase 3

221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease

NCT02484547

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What the Pipeline for Biogen Shows

According to the ClinicalTrials.gov registry, Biogen is linked to 334 US clinical trials across every stage of research activity. Of those, 21 studies are currently recruiting, about 6% of the sponsor's indexed portfolio, and 237 are already marked complete, representing roughly 71% of the total.

The phase mix for Biogen reports 84 late-stage studies (Phase 3 and Phase 4 combined) and 198 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Biogen is Multiple Sclerosis with 13 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.