Biogen
Biogen sponsors 334 registered US clinical trials on ClinicalTrials.gov, 21 of them currently recruiting, and 237 completed. 84 of these trials are in Phase 3-4 (later-stage) and 198 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Multiple Sclerosis, with 13 trials.
Trial Pipeline
334 total, page 3 of 7
Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy
NCT03283371
Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)
NCT03088956
Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease
NCT03318523
A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX
NCT03366337
MS PATHS Normative Sub-Study
NCT02996084
Efficacy and Safety of BIIB111 for the Treatment of Choroideremia
NCT03496012
A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111
NCT03507686
Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS)
NCT03222973
A Drug Interaction Study of BIIB074 and an Oral Contraceptive Regimen
NCT03324685
Effect of Itraconazole on the Pharmacokinetics of Bardoxolone Methyl in Healthy Adults
NCT03264079
Safety, Tolerability, and Pharmacokinetics of Single Doses of BIIB059 in Healthy Japanese Subjects.
NCT03224793
A Study to Assess the Pharmacodynamic Effects of SAGE-217 in Healthy Adults Using an Insomnia Model
NCT03284931
Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074
NCT03385525
Tysabri Observational Cohort Study - Multiple Sclerosis (MS) Registries
NCT03399981
Study of BIIB092 in Participants With Progressive Supranuclear Palsy
NCT03068468
Efficacy and Safety of Daclizumab in Participants With RRMS Switching From Natalizumab
NCT02881567
Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER
NCT03068130
A Study to Evaluate SAGE-217 in Participants With Essential Tremor
NCT02978781
A Tolerability Study of ALKS 8700 in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS) EVOLVE-MS-2
NCT03093324
A Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using BIIB112
NCT03116113
Long-Term Evaluation of BIIB067 (Tofersen)
NCT03070119
A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL
NCT03019185
Single-Ascending-Dose Study of BIIB076 in Healthy Volunteers and Participants With Alzheimer's Disease
NCT03056729
Scan-Rescan Sub-Study of MS PATHS
NCT04123353
A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression
NCT02978326
A Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of RTA 901 in Healthy Adults
NCT02666963
A Study to Evaluate SAGE-217 in Participants With Moderate to Severe Major Depressive Disorder
NCT03000530
New Formulation and Food Effect Study of BIIB074
NCT02951221
A Study to Evaluate SAGE-217 in Participants With Parkinson's Disease
NCT03000569
Study to Evaluate BIIB059 (Litifilimab) in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)
NCT02847598
Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST
NCT02657356
A Phase 2a Study of BIIB074 in the Treatment of Erythromelalgia
NCT02917187
A Study To Evaluate The Safety And Efficacy Of PF-04958242 In Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS)
NCT02855411
A Phase 1, Single-Ascending-Dose, Safety, Tolerability, Pharmacokinetic(PK), and Pharmacodynamic(PD) Study of BIIB068 in Healthy Participants
NCT02829541
Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke
NCT02730455
Pharmacokinetics, Safety and Tolerability of Single Doses of BIIB033 (Opicinumab) Produced by 2 Manufacturing Processes
NCT02833142
Absolute Bioavailability of a Single, Fixed Subcutaneous Dose of Aducanumab in Healthy Participants
NCT02782975
Observational Study to Characterize Real-world Clinical Outcomes With Relapsing-remitting Multiple Sclerosis (RRMS)
NCT02776072
Absorption, Metabolism, and Excretion Study of BIIB074
NCT02751905
Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers
NCT02691702
MSPT Device Usability Study
NCT02664324
Extension Study of BG00012 in Pediatric Subjects With Relapsing Remitting Multiple Sclerosis (RRMS)
NCT02555215
Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003
NCT02658916
An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 (Tofersen) in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS)
NCT02623699
Methodology Study of Novel Outcome Measures to Assess Progression of ALS
NCT02611674
A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS) EVOLVE-MS-1
NCT02634307
A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies
NCT02594124
Multiple Ascending Dose Study of Intravenously Administered BMS-986168 (BIIB092) in Patients With Progressive Supranuclear Palsy
NCT02460094
Study of the Effect of BG00012 on MRI Lesions and Pharmacokinetics in Pediatric Subjects With RRMS
NCT02410200
221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease
NCT02484547
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 135 |
| Phase 2 | 63 |
| Phase 3 | 71 |
| Phase 4 | 13 |
What the Pipeline for Biogen Shows
According to the ClinicalTrials.gov registry, Biogen is linked to 334 US clinical trials across every stage of research activity. Of those, 21 studies are currently recruiting, about 6% of the sponsor's indexed portfolio, and 237 are already marked complete, representing roughly 71% of the total.
The phase mix for Biogen reports 84 late-stage studies (Phase 3 and Phase 4 combined) and 198 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Biogen is Multiple Sclerosis with 13 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.