Abramson Cancer Center at Penn Medicine

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Abramson Cancer Center at Penn Medicine sits in the top decile of US sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count).

402 total trials 74 currently recruiting 235 completed early-phase tilt top decile by trial count

Abramson Cancer Center at Penn Medicine: 402 sponsored US clinical trials, 74 recruiting.

Abramson Cancer Center at Penn Medicine sponsors 402 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 235 completed. 3 of these trials are in Phase 3-4 (later-stage) and 175 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 20 trials.

Top-decile sponsor footprint

Abramson Cancer Center at Penn Medicine ranks in the top decile of sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

235 of 280 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

402 total, page 6 of 9

COMPLETED Early Phase 1

Pilot Study to Assess Hematologic Response in Patients With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndromes Undergoing Monotherapy With Exjade (Deferasirox)

NCT02233504

COMPLETED

FDG-PET/CT Imaging as Early Predictor of DP

NCT02476734

COMPLETED

Initial Evaluation of a Telomerase-based Circulating Tumor Cell Assay in Bladder Cancer Cohorts

NCT02246738

COMPLETED NA

Multiplex Testing for Evaluation of Breast Cancer Risk, Longitudinal Study

NCT02514499

COMPLETED

Assessment of Cancer Concerns at the End of Treatment (ACE)

NCT02514486

COMPLETED Phase 2

Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

NCT02207439

COMPLETED

Adherence to Aromatase Inhibitors: The Role of Partners

NCT02753985

COMPLETED

Validation of Edema-invariant Multi-shell High Angular Resolution Diffusion Imaging (msHARDI)-Based Tractography With Intra-operative Cortical Stimulation

NCT02559401

COMPLETED

Patient-Centered Acupuncture for Pain (PCAP)

NCT02152020

COMPLETED NA

A Pilot Study at a Single-Institution of Pregabalin in the Management of Mucositis Pain in Patients Undergoing Chemoradiation Therapy to the Head and Neck.

NCT02277548

COMPLETED Phase 1

Acupuncture Feasibility Trial for Dyspnea in Lung Cancer

NCT02094950

TERMINATED

Functional Outcome Measures for Head and Neck Patients

NCT02530112

COMPLETED

[18F] Flourothymidine (FLT) PET/CT Imaging for Gynecologic Cancers

NCT02108457

COMPLETED Phase 2

A Single-arm Phase II Study of Post-Transoral Robotic Surgery (TORS) Alone to the Primary Tumor Site and Selective Neck Dissection (SND) Followed by Adjuvant Radiation Therapy (+/- Chemotherapy) to the Regional Nodes for Advanced Stage, Human Papilloma Virus (HPV) Positive, Oropharyngeal Cancer

NCT02159703

COMPLETED Phase 1

A Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer

NCT02030860

TERMINATED NA

Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures

NCT02881047

COMPLETED Phase 1

Brentuximab Vedotin and Chemotherapy in CD30+ PMBL, Diffuse Large B-Cell, and Grey Zone Lymphoma Patients

NCT01994850

TERMINATED Phase 1

Phase 1-2 Trial HCQ Plus TACE in Unresectable HCC

NCT02013778

COMPLETED NA

Suitability of DCE-MRI for Detection of Vascular Changes After VBT

NCT01991808

COMPLETED NA

A Pilot Study to Evaluate Radiotherapy-Induced Anti-Tumor Immunity in Metastatic Carcinoma of the Pancreas

NCT01985958

COMPLETED

Surveillance Markers of Utility for Recurrence After Neoadjuvant Chemotherapy for Breast Cancer

NCT02830282

COMPLETED Phase 1

A Phase I Trial of Vemurafenib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma

NCT01897116

COMPLETED

Study Of Circulating Multiple Myeloma Cells As A Biomarker of MGUS And SMM

NCT01958528

COMPLETED NA

HPV Serum DNA Levels Predicting Outcome in p16+ Squamous Cell Head and Neck Cancer

NCT01984359

COMPLETED Phase 1

APBI Proton Feasibility and Phase II Study

NCT01839838

COMPLETED Phase 2

A Randomized Phase II/Genomic Trial of Two Chemotherapy Regimens in Patients With Resected Pancreatic Adenocarcinoma

NCT01839799

COMPLETED

CTCs for High Grade Glioma

NCT02558335

COMPLETED

A Feasibility Study Followed By A Randomized Phase II Study Of Yoga For Radiation Therapy Side Effects In Prostate Cancer

NCT02135653

COMPLETED NA

Multiple Myeloma and Exercise

NCT01809717

COMPLETED NA

Yoga for Breast Cancer

NCT01985945

COMPLETED Phase 2

Phase II Maraviroc for GVHD Prevention

NCT01785810

COMPLETED Phase 2

Etirinotecan Pegol (NKTR-102) in NSCLC

NCT01773109

COMPLETED

A Study of the Communication of Genetic Test Results By Telephone: A Multi-Center Study

NCT01736345

COMPLETED

The Detection Of Circulating Tumor Cells (CTC) In Patients With NSCLC Undergoing Definitive Radiotherapy Or Chemoradiotherapy

NCT02135679

COMPLETED Early Phase 1

Autophagy Induction After Bortezomib for Myeloma

NCT01594242

COMPLETED NA

Functional MRI Use in Prostate Radiation Treatment Planning

NCT01985932

COMPLETED Phase 1

CRLX101 Plus Bevacizumab in Advanced RCC

NCT01625936

COMPLETED Early Phase 1

Multi-peptide Vaccine With Basilixumab for Breast Cancer

NCT01660529

COMPLETED Phase 2

Dovitinib in Neuroendocrine Tumors

NCT01635907

COMPLETED Phase 1

Maintenance Lenalidomide in Lymphoma

NCT01575860

COMPLETED Phase 2

Ruxolitinib in Estrogen Receptor Positive Breast Cancer

NCT01594216

COMPLETED Phase 1

Phase 1 Study of Preoperative Gemcitabine Plus CP-870, 893 Followed by Addition of CP-870,893 to Standard -Of-care Adjuvant Chemoradiation for Patients With Newly Diagnosed Resectable Pancreatic Carcinoma

NCT01456585

COMPLETED NA

Proton Radiotherapy for Stage I, IIA, and IIB Seminoma

NCT01557790

COMPLETED Phase 1

Topical Resiquimod for the Treatment of Early Stage Cutaneous T Cell Lymphoma (CTCL)

NCT01676831

COMPLETED

Does Cryofixation of Skin Specimens Affect Quality of Subsequent Formalin Fixed Paraffin Embedded H and E Histology

NCT01540695

COMPLETED Phase 1

MLN8237 in Head and Neck Cancer

NCT01540682

COMPLETED NA

Peripheral vs. Selective Tumor Marker Venous Sampling in Prostate Cancer

NCT02479945

COMPLETED Phase 4

A Study of Effects of Fesoterodine in Men at High Risk for Overactive Bladder/Detrusor Overactivity Post Robotic-Assisted Lap. Prostatectomy

NCT01661166

COMPLETED Phase 1

Adjuvant Proton Therapy or IMRT for the Treatment of Bladder Cancer

NCT01520038

COMPLETED Phase 1

A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer

NCT01506973

← Previous Page 6 of 9 Next →

Phase Distribution

PhaseTrial count
Phase 1 113
Phase 2 62
Phase 3 1
Phase 4 2

What is open in the Abramson Cancer Center at Penn Medicine pipeline

74 recruiting of 402 indexed (18% open); 235 completed (58%).

Phase mix: 3 late (III/IV) vs 175 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (20 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Abramson Cancer Center at Penn Medicine: open-pipeline peers nationwide

Peers matched on 402 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 10%15%20%25% Total trials Recruiting share Abramson Cancer Center at Penn MedicineCase Comprehensive Cancer CenterUniversity of NebraskaTakedaUniversity of Kansas Medical CenterUniversity of Maryland, BaltimoreHenry Ford Health SystemNew York Institute of TechnologyUniversity of California, San Diego
Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 402 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Abramson Cancer Center at Penn Medicine page

402 registered trials is a research-attention snapshot, not an endorsement of Abramson Cancer Center at Penn Medicine or any single study.

  • 74 of Abramson Cancer Center at Penn Medicine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Abramson Cancer Center at Penn Medicine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Abramson Cancer Center at Penn Medicine pipeline card: 402 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.