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NCT01897116 · ClinicalTrials.gov registry record · Phase 1
A Phase I Trial of Vemurafenib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma
A Phase 1 study, sponsored by Abramson Cancer Center at Penn Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT01897116: Completed Phase 1 study, sponsored by Abramson Cancer Center at Penn Medicine.
NCT01897116 is a Phase 1 study that has completed, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01897116, a Phase 1 study, has completed, sponsored by Abramson Cancer Center at Penn Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
This is a Phase I study combining vemurafenib and hydroxychloroquine in the treatment of BRAF V600E+ metastatic melanoma.
Interventions
- DRUG Hydroxychloroquine (HCQ)
- DRUG Vemurafenib (VEM)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2013-06 |
| Est. Completion | 2016-10-05 |
| Phase | Phase 1 |
What the finished NCT01897116 record still lists
NCT01897116 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which Hydroxychloroquine (HCQ) is the first listed.
NCT01897116 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01897116 about?
NCT01897116 is a clinical study titled "A Phase I Trial of Vemurafenib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma". This is a Phase I study combining vemurafenib and hydroxychloroquine in the treatment of BRAF V600E+ metastatic melanoma.
What is the current status of trial NCT01897116?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2013-06. Estimated completion is 2016-10-05.
What interventions are being tested in trial NCT01897116?
The interventions under investigation include: Hydroxychloroquine (HCQ) (DRUG), Vemurafenib (VEM) (DRUG).
Who is sponsoring clinical trial NCT01897116?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01897116's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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