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NCT02881047 · ClinicalTrials.gov registry record · NA
Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures
A NA study, sponsored by Abramson Cancer Center at Penn Medicine.
- Terminated
- Registry status
- NA
- Development phase
- 8
- Enrollment target
NCT02881047: Clinical Trial NA study, sponsored by Abramson Cancer Center at Penn Medicine.
NCT02881047 is a NA study that was terminated before completion, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02881047, a NA study, was terminated before completion, sponsored by Abramson Cancer Center at Penn Medicine.
- TERMINATED
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
Study Summary
Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplant.Chronic GVHD is characterized by skin thickening and tightening. Advanced sclerosis can lead to reduced range of motion and incapacitating joint contractures. Once present, there are few therapeutic options. We will treat sclerosis and limb contractures with an ablative fractional laser, a device FDA-approved for scar treatment. This approach has successfully treated contracturesdue to burn scars.
Primary Outcome
Range of motion (flexion, extension, supination, pronation) of the target joint (measured in degrees, using a goniometer).
Interventions
- DEVICE CO2 Laser
- RADIATION Ultrasound
- DIAGNOSTIC_TEST Skin Biopsy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2013-11-11 |
| Est. Completion | 2016-08-19 |
| Phase | NA |
Why NCT02881047 stopped before completion
NCT02881047 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which CO2 Laser is the first listed.
NCT02881047 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02881047 about?
NCT02881047 is a clinical study titled "Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures". Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplant.Chronic GVHD is characterized by skin thickening and tightening. Advanced sclerosis can lead to reduced range of motion and incapacitating joint contractures. Once present, there are few therapeutic options....
What is the current status of trial NCT02881047?
This trial is currently terminated. It is a NA study. The enrollment target is 8 participants. The study started on 2013-11-11. Estimated completion is 2016-08-19.
What interventions are being tested in trial NCT02881047?
The interventions under investigation include: CO2 Laser (DEVICE), Ultrasound (RADIATION), Skin Biopsy (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT02881047?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02881047's enrollment target sits among peer trials
8 1976th of 2000 higher than 19 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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