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NCT01540682 · ClinicalTrials.gov registry record · Phase 1
MLN8237 in Head and Neck Cancer
A Phase 1 study, sponsored by Abramson Cancer Center at Penn Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
NCT01540682: Completed Phase 1 study, sponsored by Abramson Cancer Center at Penn Medicine.
NCT01540682 is a Phase 1 study that has completed, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01540682, a Phase 1 study, has completed, sponsored by Abramson Cancer Center at Penn Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
This study will evaluate the initial safety and effectiveness of an investigational drug, MLN8237, added to routine radiation therapy and cetuximab in patients with head and neck cancer. This study will also determine the highest dose of MLN8237 that can be given together with cetuximab and radiation therapy without causing severe side effects.
Interventions
- RADIATION Radiotherapy
- DRUG Cetuximab
- DRUG MLN8237
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2012-02 |
| Phase | Phase 1 |
What the finished NCT01540682 record still lists
NCT01540682 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 3 interventions - of which Radiotherapy is the first listed.
NCT01540682 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01540682 about?
NCT01540682 is a clinical study titled "MLN8237 in Head and Neck Cancer". This study will evaluate the initial safety and effectiveness of an investigational drug, MLN8237, added to routine radiation therapy and cetuximab in patients with head and neck cancer. This study will also determine the highest dose of MLN8237 that can be given together with cetuximab and radiatio...
What is the current status of trial NCT01540682?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2012-02.
What interventions are being tested in trial NCT01540682?
The interventions under investigation include: Radiotherapy (RADIATION), Cetuximab (DRUG), MLN8237 (DRUG).
Who is sponsoring clinical trial NCT01540682?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01540682's enrollment target sits among peer trials
9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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