Abramson Cancer Center at Penn Medicine

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Abramson Cancer Center at Penn Medicine sits in the top decile of US sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count).

402 total trials 74 currently recruiting 235 completed early-phase tilt top decile by trial count

Abramson Cancer Center at Penn Medicine: 402 sponsored US clinical trials, 74 recruiting.

Abramson Cancer Center at Penn Medicine sponsors 402 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 235 completed. 3 of these trials are in Phase 3-4 (later-stage) and 175 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 20 trials.

Top-decile sponsor footprint

Abramson Cancer Center at Penn Medicine ranks in the top decile of sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

235 of 280 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

402 total, page 7 of 9

COMPLETED Phase 1

Radvax™: A Stratified Phase I/II Dose Escalation Trial OF Hypofractionated Radiotherapy Followed BY Ipilimumab IN Metastatic Melanoma

NCT01497808

COMPLETED

BETERNet Notch Signaling and Novel Biomarkers for Barretts Esophagus

NCT01484925

TERMINATED Phase 1

A Phase I-II Open Label Non-Randomized Study Using TL32711 for Patients With Acute Myelogenous Leukemia, Myelodysplastic Syndrome and Acute Lymphoblastic Leukemia

NCT01486784

TERMINATED Phase 2

Brivanib Metastatic Renal Cell Carcinoma

NCT01253668

COMPLETED Phase 1

Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma

NCT01510119

COMPLETED NA

Proton Radiotherapy for Upper Gastrointestinal Malignancies

NCT01449864

COMPLETED

Experience of Non-Melanoma Skin Cancer (NMSC) Mohs Surgery Project

NCT01452984

COMPLETED Early Phase 1

Intraoperative Imaging of Breast Cancer With Indocyanine Green

NCT01796041

COMPLETED Early Phase 1

Cyclophosphamide and Pulse Dexamethasone With Rapamycin or Hydroxychloroquine

NCT01396200

COMPLETED

Pelvic Floor Disorders in Survivors of Gynecologic Malignancies

NCT01370122

COMPLETED

Cardiovascular Effects of Sunitinib Therapy (CREST)

NCT01370109

TERMINATED Phase 1

A Clinical Trial of Autologous Oxidized Tumor Cell Lysate Vaccine For Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer

NCT01312389

COMPLETED NA

F18 EF5 PET/CT Imaging in Patients With Brain Metastases From Breast Cancer

NCT01985971

COMPLETED Phase 1

PD0332991/Paclitaxel in Advanced Breast Cancer

NCT01320592

TERMINATED Phase 1

Autologous T-Cells Combined With Autologous OC-DC Vaccine in Ovarian Cancer

NCT01312376

COMPLETED Phase 2

Effect of Donepezil on Smoking

NCT01250977

COMPLETED

The Effects of Radiation in Reconstructed Breasts

NCT01292772

COMPLETED

DIBH Proton Planning

NCT01386697

COMPLETED Early Phase 1

Pazopanib/DCE-MRIs in Renal Cell Carcinoma (RCC)

NCT01221506

COMPLETED Phase 1

Hydroxychloroquine and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT00568880

COMPLETED NA

A Volume, Motion, and Anatomically Adaptive Approach to Photon and Proton Beam Radiotherapy

NCT02130427

COMPLETED Phase 1

Phase 1 Trial of the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus Plus Radiation Therapy (RT) for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy

NCT01548807

COMPLETED

Skull Base and Low Grade Glioma Neurocognitive Magnetic Resonance Imaging (MRI) Study

NCT01212731

COMPLETED Phase 1

FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

NCT01206530

COMPLETED

BCRL Prevention Pilot

NCT01166672

COMPLETED

Physical Functional Side Effects of Taxane Chemotherapy for Breast Cancer

NCT01153282

TERMINATED Phase 2

Proton Radiotherapy for Extremity Soft Tissue Sarcoma

NCT01561495

TERMINATED Phase 1

Eltrombopag in Elderly Acute Myelogenous Leukemia (AML)

NCT01113502

TERMINATED Phase 2

Phase II Study of Bexarotene in Patients With Acute Myeloid Leukemia

NCT00615784

COMPLETED Early Phase 1

Autologous OC-DC Vaccine in Ovarian Cancer

NCT01132014

COMPLETED

LIVESTRONG Survivorship Care Plan: Continued Data Collection and Follow Up Survey

NCT02559323

COMPLETED Phase 1

Combination Gene Transfer and Chemotherapy

NCT01119664

COMPLETED Phase 2

Anti-TGF Monoclonal Antibody (GC1008) in Relapsed Malignant Pleural Mesothelioma

NCT01112293

COMPLETED NA

Proton Radiation for Chordomas and Chondrosarcomas

NCT01449149

TERMINATED Phase 2

Proton Beam Radiation With Concurrent Chemotherapy and Nelfinavir for Inoperable Stage III Non Small Cell Lung Cancer (NSCLC)

NCT01108666

COMPLETED Phase 1

Proton Radiation For Meningiomas and Hemangiopericytomas

NCT01117844

COMPLETED Phase 1

Tremelimumab and CP-870,893 in Patients With Metastatic Melanoma

NCT01103635

COMPLETED NA

Proton Radiotherapy for Recurrent Tumors

NCT01126476

COMPLETED

Single Nucleotide Polymorphism (SNP) Panels and Risk Assessment in Women Undergoing Mammography

NCT01124019

COMPLETED Phase 1

Proton Beam Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Can Be Removed By Surgery

NCT01076231

COMPLETED Phase 1

Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

NCT01024907

COMPLETED Phase 2

Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer

NCT01037790

COMPLETED Phase 2

Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck

NCT01044433

COMPLETED Phase 1

Sorafenib Tosylate and Chemoembolization in Treating Patients With Unresectable Liver Cancer

NCT01042041

TERMINATED NA

Proton Radiation Therapy in Treating Patients With Prostate Cancer

NCT01045226

COMPLETED Phase 1

DC Vaccine for Patients With Ductal Carcinoma In Situ

NCT02061332

COMPLETED NA

Magnetic Resonance Imaging in Evaluating Response to RadiationTherapy in Patients With High Grade Glioma

NCT01018329

TERMINATED NA

Flexitouch Lymphedema System in Treating Stage II Lymphedema in Patients With Breast Cancer

NCT01019512

TERMINATED NA

Magnetic Resonance Imaging-Based Radiation Therapy and Cisplatin in Patients With Stage I, Stage II, Stage III, or Stage IV Cervical Cancer

NCT01016561

COMPLETED Phase 2

Cognitive Behavioral Therapy With or Without Armodafinil in Treating Cancer Survivors With Insomnia and Fatigue After Chemotherapy

NCT01019187

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Phase Distribution

PhaseTrial count
Phase 1 113
Phase 2 62
Phase 3 1
Phase 4 2

What is open in the Abramson Cancer Center at Penn Medicine pipeline

74 recruiting of 402 indexed (18% open); 235 completed (58%).

Phase mix: 3 late (III/IV) vs 175 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (20 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Abramson Cancer Center at Penn Medicine: open-pipeline peers nationwide

Peers matched on 402 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 10%15%20%25% Total trials Recruiting share Abramson Cancer Center at Penn MedicineCase Comprehensive Cancer CenterUniversity of NebraskaTakedaUniversity of Kansas Medical CenterUniversity of Maryland, BaltimoreHenry Ford Health SystemNew York Institute of TechnologyUniversity of California, San Diego
Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 402 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Abramson Cancer Center at Penn Medicine page

402 registered trials is a research-attention snapshot, not an endorsement of Abramson Cancer Center at Penn Medicine or any single study.

  • 74 of Abramson Cancer Center at Penn Medicine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Abramson Cancer Center at Penn Medicine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Abramson Cancer Center at Penn Medicine pipeline card: 402 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.