Abramson Cancer Center at Penn Medicine

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Abramson Cancer Center at Penn Medicine sits in the top decile of US sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count).

402 total trials 74 currently recruiting 235 completed early-phase tilt top decile by trial count

Abramson Cancer Center at Penn Medicine: 402 sponsored US clinical trials, 74 recruiting.

Abramson Cancer Center at Penn Medicine sponsors 402 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 235 completed. 3 of these trials are in Phase 3-4 (later-stage) and 175 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 20 trials.

Top-decile sponsor footprint

Abramson Cancer Center at Penn Medicine ranks in the top decile of sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

235 of 280 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

402 total, page 5 of 9

TERMINATED Phase 2

Maintenance Rucaparib in BRCA1, BRCA2 or PALB2 Mutated Pancreatic Cancer That Has Not Progressed on Platinum-based Therapy

NCT03140670

COMPLETED

Circulating Tumor Material in Colorectal Cancer and Melanoma

NCT02907086

TERMINATED Early Phase 1

Pilot Study of Blinatumomab in Combination With Salvage Autologous Stem Cell Transplantation for Patients With Refractory Multiple Myeloma

NCT03173430

COMPLETED

A Phase I, Single-center, Mixed Methods Study ON THE Health Outcomes OF Visual Self Expression

NCT03155672

COMPLETED

A Pilot Study OF Diffusion Weighted MRI TO Assess Esophageal Tumor Resonse TO Neoadjuvant Chemoradiation

NCT03151642

COMPLETED Phase 1

Galunisertib (LY2157299) Plus Stereotactic Body Radiotherapy (SBRT) in Advanced Hepatocellular Carcinoma (HCC)

NCT02906397

TERMINATED

Early FDG PET/CT Imaging as a Measure of Response in Patients With Non-Hodgkin Lymphoma on Lenalidomide

NCT03065790

TERMINATED Early Phase 1

A Randomized Study to Establish the Efficacy of Oral Ice Exposure During Oxaliplatin Infusion in Preventing Oral Cold Sensitivity

NCT03427021

COMPLETED

A Pilot Study to Develop Predictive Biomarkers for the Response to Immunotherapy in Lung Cancer

NCT03047616

COMPLETED NA

Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain

NCT02906787

COMPLETED

Intraoperative Imaging With ICG Registry

NCT02640170

COMPLETED

Imaging FDG Flare in Melanoma

NCT02791594

TERMINATED

Imaging of in Vivo Sigma-2 Receptor Expression With 18F-ISO-1 Positron Emission Tomography in Metastatic Breast Cancer

NCT03057743

COMPLETED NA

FDG PET/CT in Lung Cancer Staging

NCT02738398

COMPLETED

Neutrophil-to-Lymphocyte Ratio in Bladder Cancer: A Secondary Biomarker Analysis of SWOG 8710

NCT02756637

COMPLETED

Assessing the Impact of Electronic Capture of Patient Reported Outcomes in Radiation Oncology

NCT02756767

COMPLETED Early Phase 1

C-Acetate PET/CT Imaging to Evaluate Treatment Changes in Prostate Cancer

NCT02715583

COMPLETED Phase 2

Randomized Embolization Trial for NeuroEndocrine Tumor Metastases to the Liver

NCT02724540

TERMINATED NA

Early FDG PET in Melanoma

NCT02716077

COMPLETED Phase 1

Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers

NCT02639026

COMPLETED Phase 1

Pembrolizumab in Patients Failing to Respond to or Relapsing After CAR T Cell Therapy for Relapsed or Refractory Lymphomas

NCT02650999

COMPLETED Phase 1

A Trial of Ribocilcib (LEE011) and Weekly Paclitaxel in Patients With Rb+ Advanced Breast Cancer

NCT02599363

TERMINATED

Physician-Patient Communication and Expectations Regarding Ovarian Cancer Prognosis

NCT02769546

TERMINATED NA

A Non-Invasive Cervical Cancer Screening Modality: A Pilot Study

NCT02767726

COMPLETED

Optional Sub-study to Intraoperative Imaging With ICG Registry

NCT02651246

COMPLETED NA

Exercise and Colon Cancer

NCT02250053

TERMINATED

Serial [18F]Fluorodeoxyglucose ([18F]FDG )PET/CT as a Biomarker of Therapeutic Response in Anti-PD1/PDL1 Therapy

NCT02608528

COMPLETED Phase 1

Study of Neo-adjuvant RO7009789 Alone or Neo-adjuvant RO7009789 Plus Nab-Paclitaxel and Gemcitabine Followed by Adjuvant RO7009789 Plus Nab-Paclitaxel and Gemcitabine for Patients With Newly Diagnosed Resectable Pancreatic Carcinoma

NCT02588443

COMPLETED

Gut Microbiota And Radiotherapy

NCT02559349

COMPLETED

A Study Of TeleGenetics Versus Usual Care To Increase Access To Cancer Genetic Services

NCT02517554

TERMINATED NA

Evaluating the Effect of Perioperative Caloric Restriction Program on Perioperative Outcomes in Patients With Obesity and Endometrial Cancer

NCT02665962

COMPLETED Phase 1

Indocyanine Green for Central Nervous System Tumors

NCT02710240

COMPLETED

Cardiotoxicity of Radiation Therapy (CTRT)

NCT02769299

COMPLETED NA

WISER After Ovarian Cancer - Exercise Pilot Study

NCT02529150

TERMINATED Phase 1

Autologous OC-L Vaccine and Ovarian Cancer

NCT02452775

TERMINATED Phase 2

Dietary Flaxseed in NSCLC

NCT02475330

COMPLETED Phase 1

A Tissue Collection Study of Pembrolizumab (MK-3475) in Subjects With Resectable Advanced Melanoma

NCT02434354

COMPLETED

Study on Breast Cancer Patient Perspectives of Exercise

NCT02559362

COMPLETED

The Utility of Circulating Tumor Cells as Confirmation of Pathologic Diagnosis in Patients With Suspected Early Stage Non-small Cell Lung Cancer

NCT02380196

COMPLETED NA

Improving Clinical Trial Awareness in NSCLC: Pilot Testing A Novel Healthcare IT Platform for Incorporating Education at the Point of Care

NCT02558998

COMPLETED Phase 1

A Study of Nelfinavir Added to Cisplatin Chemotherapy Concurrent With Pelvic Radiation for Locally Advanced Cervical Cancer (II-IVA)

NCT02363829

COMPLETED NA

Clinical Utility of a Low-Cost Hand-Held Breast Scanner

NCT02762565

COMPLETED Phase 2

Phase II Study of Pembrolizumab After Curative Intent Treatment for Oligometastatic Non-Small Cell Lung Cancer

NCT02316002

COMPLETED Phase 1

RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers

NCT02303990

COMPLETED NA

Evaluating Therapeutic Response to Novo-TTF

NCT02441322

COMPLETED Early Phase 1

IFN-DLI for Relapsed Acute Leukemia After Allo-SCT

NCT02331706

COMPLETED

Smart Adult Living After Childhood Cancer (SmartALACC) Online Care Plans: Feasibility and Patient Satisfaction

NCT02559219

COMPLETED

Healthy Human Control Blood Collection for Validation of Biomarker Assay

NCT02302885

COMPLETED Phase 1

Dabrafenib, Trametinib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma

NCT02257424

COMPLETED

PAIN-LESS: Understanding and Alleviating Pain for Cancer Patients in Academic and Community Hospitals

NCT02559375

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Phase Distribution

PhaseTrial count
Phase 1 113
Phase 2 62
Phase 3 1
Phase 4 2

What is open in the Abramson Cancer Center at Penn Medicine pipeline

74 recruiting of 402 indexed (18% open); 235 completed (58%).

Phase mix: 3 late (III/IV) vs 175 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (20 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Abramson Cancer Center at Penn Medicine: open-pipeline peers nationwide

Peers matched on 402 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 10%15%20%25% Total trials Recruiting share Abramson Cancer Center at Penn MedicineCase Comprehensive Cancer CenterUniversity of NebraskaTakedaUniversity of Kansas Medical CenterUniversity of Maryland, BaltimoreHenry Ford Health SystemNew York Institute of TechnologyUniversity of California, San Diego
Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 402 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Abramson Cancer Center at Penn Medicine page

402 registered trials is a research-attention snapshot, not an endorsement of Abramson Cancer Center at Penn Medicine or any single study.

  • 74 of Abramson Cancer Center at Penn Medicine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Abramson Cancer Center at Penn Medicine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Abramson Cancer Center at Penn Medicine pipeline card: 402 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.