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Type 1 Diabetes: early-phase trial registry
79 of 199 indexed Type 1 Diabetes trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #50 of 28,707 conditions by registered trial count.
199 US clinical trials · 79 currently recruiting · #50 of 28,707 conditions by registered trial count
Type 1 Diabetes: 199 US clinical trials tracked, 79 recruiting.
Type 1 Diabetes is the subject of 199 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 54 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 16 of these trials.
Enrollment posture brief
Registry condition type-1-diabetes
OPEN 79 | RECR 40% | LATE 21 | EARLY 54 | RANK #50 | SPON 16
Volume-matched condition peers
Nearest open-share peer: Pregnancy (40% recruiting · 194 trials)
Type 1 Diabetes lists 79 open slots (40% of 199 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 1 Diabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Type 1 Diabetes is recruiting above its size-band peers.
79 of 199 indexed trials (39.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 1 Diabetes trials is spread across many organizations.
University of Colorado, Denver accounts for 16 of 199 trials (8%). 97 distinct sponsors appear on at least one study for this condition label.
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Most Type 1 Diabetes trials plan to enrol fewer than 100 people.
Median target enrolment is 43 among the 199 trials that report a genuine target (sentinel values excluded). 141 of those (70.9%) plan for fewer than 100 participants.
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Type 1 Diabetes research is mostly interventional.
169 interventional and 30 observational studies make up this index (84.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
199 total, page 3 of 4
Effects of GRA in Patients With Type 1
University of California, San Diego
NCT04779645
Development of Novel Biomarkers for the Early Diagnosis of Type 1 Diabetes
AdventHealth Translational Research Institute
NCT04164966
Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes
Children's Hospital of Philadelphia
NCT04238949
A 12-week Pilot Nutrition Intervention for Children With New Diagnosis of Stage 3 Type 1 Diabetes (T1D)
Milton S. Hershey Medical Center
NCT06640478
Adrenergic System in Islet Transplantation
University of Pennsylvania
NCT03079921
A Safety, Tolerability, and Efficacy Study of VX-264 in Participants With Type 1 Diabetes
Vertex Pharmaceuticals Incorporated
NCT05791201
Extension for Community Health Outcomes (ECHO) Diabetes Program
University of Florida
NCT06552923
Family Management of Childhood Diabetes Study
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00340938
A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy
Eli Lilly and Company
NCT05463744
A 2-Month Safety Follow-Up Trial
Mannkind Corporation
NCT00741429
Identifying Driving Risk Factors in Type 1 Diabetes and Their Reduction Via Internet Program (DiabetesDriving.Com)
University of Virginia
NCT01563887
Study to Compare Efficacy of the MiniMed Paradigm REAL-Time System Vs. MDI in Subjects Naive to Insulin Pump Therapy
Medtronic Diabetes
NCT00417989
Randomized Study of Real-Time Continuous Glucose Monitors (RT-CGM) in the Management of Type 1 Diabetes
Jaeb Center for Health Research
NCT00406133
Sweetgoals for Type 1 Diabetes
Trustees of Dartmouth College
NCT04646473
Investigation Into the Effects Upon Brain Response to Change in Circulating Glucose Levels in Diabetes Mellitus
Yale University
NCT00580710
Characteristics of Persons With an Eating Disorder and Type 1 Diabetes
HealthPartners Institute
NCT00945711
Automated Insulin Delivery for Inpatients With Dysglycemia
Emory University
NCT06418880
Can Glucose Monitoring Improve (CGMi Study)
Joslin Diabetes Center
NCT01472159
Testing MST to Improve Adherence Among Youth With Chronic Poor Metabolic Control
Wayne State University
NCT00519935
ADJUnct Semaglutide Treatment in Type 1 Diabetes
Viral N. Shah
NCT05537233
Hybrid Closed Loop Therapy and Verapamil for Beta Cell Preservation in New Onset Type 1 Diabetes
Jaeb Center for Health Research
NCT04233034
Bromocriptine Quick Release (BCQR) as Adjunct Therapy in Type 1 Diabetes
University of Colorado, Denver
NCT02544321
Effect of Apidra Compared to Humalog in Decreasing Post-Prandial Hyperglycemia
University of Florida
NCT01621776
In Clinic Evaluation of the PLGM Feature
Medtronic Diabetes
NCT02130284
Intravenous Insulin vs Subcutaneous Insulin Infusion in Intrapartum Management of Type 1 Diabetes Mellitus
Gianna Wilkie
NCT04599075
Assessment of Sleep and Sleep Disruptors in Adolescents With Type 1 Diabetes
University of Colorado, Denver
NCT05370339
PROCHYMAL® (Human Adult Stem Cells) for the Treatment of Recently Diagnosed Type 1 Diabetes Mellitus (T1DM)
Mesoblast
NCT00690066
Iterative Beta Testing of Videos for the DIPPer Academy
University of Kansas Medical Center
NCT03385265
Early Markers of Disease and Response to Therapy
Sandra Lord, MD
NCT04118153
Lantus in the Treatment of Type 1 Diabetes Children
Baylor College of Medicine
NCT00206401
Comparison of Glargine to Degludec Insulin Transition With or Without a Bridging Glargine Dose
University of Washington
NCT04623086
Insulet Artificial Pancreas Early Feasibility Study
Insulet Corporation
NCT02897557
Inpatient Evaluation of an Automated Closed-Loop Control-to-Range System
Jaeb Center for Health Research
NCT01271023
Eating Disorder Prevention Program for Women With T1D
Stanford University
NCT05264376
Monocyte Function and Inflammation in Type 1 Diabetes and Its Modulation
University of California, Davis
NCT00441844
Diabetes Closed-Loop Project 6 (DCLP6): Fully Automated Closed-Loop Control in Type 1 Diabetes Using Meal Anticipation
University of Virginia
NCT04877730
Development of Predictive Biomarkers
Medical College of Wisconsin
NCT03423862
Vitamin D and Residual Beta-Cell Function in Type 1 Diabetes
Benjamin U. Nwosu, MD
NCT03046927
Hypoglycemia Associated Autonomic Failure in Type 1 DM
Vanderbilt University
NCT00592670
Analysis of B Cells From Autoimmune Individuals
University of Colorado, Denver
NCT02747277
Impact of Hybrid Closed-Loop Systems on Sleep and Psychosocial Outcomes in Youth With T1D and Their Parents
University of Colorado, Denver
NCT04431947
Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Diabetes
University of Colorado, Denver
NCT02502071
School Centered Telemedicine Program for Children With Type 1 Diabetes Mellitus
State University of New York - Upstate Medical University
NCT00566475
HCT Cash-Only INcentive to Promote Mealtime Insulin DOSE Engagement
Children's Mercy Hospital Kansas City
NCT04621890
Promoting Adolescent Investment In Diabetes Care
Harvard Pilgrim Health Care
NCT04516694
Self-Management in Young Adults With Type 1 Diabetes
Case Western Reserve University
NCT04975230
Effect of Vitamin D on the Honeymoon Period in Children and Adolescents With Type 1 Diabetes
Nationwide Children's Hospital
NCT01724190
Lunch Time Insulin Injection by School Nurse for Poorly Controlled Diabetes
Baylor College of Medicine
NCT00340613
Use of Mobile-based Technologies to Improve Diabetes Self-management and Postprandial Glucose Control
Joslin Diabetes Center
NCT02556398
Measurement of Glucose Metabolism in Humans: Effect of Recurrent Hypoglycemia on Hypothalamic GABA
University of Minnesota
NCT02829593
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 30 |
| Phase 2 | 24 |
| Phase 3 | 11 |
| Phase 4 | 10 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 1 Diabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 1 Diabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 1 Diabetes page
199 registered trials, 79 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 79 Type 1 Diabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Colorado, Denver sponsors the most Type 1 Diabetes trials on record, review their full trial history before evaluating a specific study. See University of Colorado, Denver's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 1 Diabetes condition card totals 199 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.