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NCT02747277 · ClinicalTrials.gov registry record
Analysis of B Cells From Autoimmune Individuals
A clinical trial of Type 1 Diabetes and Rheumatoid Arthritis, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 46
- Enrollment target
- 1
- Study location
NCT02747277: Completed study of Type 1 Diabetes and Rheumatoid Arthritis, sponsored by University of Colorado, Denver.
NCT02747277 is a study of Type 1 Diabetes and Rheumatoid Arthritis that has completed, run by University of Colorado, Denver. The registered enrollment target is 46 participants, below the 767-participant average among 198 other Type 1 Diabetes trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02747277, a study of Type 1 Diabetes and Rheumatoid Arthritis, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
This observational study aims at finding out if individual with autoimmunity exhibit increased numbers of B cells that express two types (instead of one type) of antibodies, and if B cells of individuals genetically susceptible to autoimmunity display defects in the biological process of tolerance, which removes B cells that participate in autoimmunity.
Primary Outcome
For peripheral adult blood, the main outcome measure is the frequency of κ/λ (kappa to lambda ratios) dual immunoglobulin B cells within the overall B (CD19+ or CD20+) cell population. The collected data will be aggregated as the average frequency of κ/λ B cells in subjects with autoimmunity relative to healthy controls.
Conditions Studied
Study Locations (1)
Colorado
- University of Colorado - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2016-05 |
| Est. Completion | 2022-01 |
What the finished NCT02747277 record still lists
NCT02747277 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 767-participant average among 198 other Type 1 Diabetes trials with a reported enrollment target (94% lower).
The record links to 3 conditions, with Type 1 Diabetes appearing as the primary indexed condition, and to 0 interventions.
NCT02747277 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT02747277 about?
NCT02747277 is a clinical study titled "Analysis of B Cells From Autoimmune Individuals". This observational study aims at finding out if individual with autoimmunity exhibit increased numbers of B cells that express two types (instead of one type) of antibodies, and if B cells of individuals genetically susceptible to autoimmunity display defects in the biological process of tolerance, ...
What is the current status of trial NCT02747277?
This trial is currently completed. The enrollment target is 46 participants. The study started on 2016-05. Estimated completion is 2022-01.
What conditions does trial NCT02747277 study?
This clinical trial studies the following conditions: Type 1 Diabetes, Rheumatoid Arthritis, Lupus Erythematosus.
Who is sponsoring clinical trial NCT02747277?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02747277 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02747277's enrollment target sits among peer trials
46 95th of 198 higher than 103 of 198 other Type 1 Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Type 1 Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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