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NCT04779645 · ClinicalTrials.gov registry record · Phase 2

Effects of GRA in Patients With Type 1

A Phase 2 study of Type 1 Diabetes, sponsored by University of California, San Diego.

Active
Registry status
Phase 2
Development phase
30
Enrollment target
1
Study location

NCT04779645 is a Phase 2 study of Type 1 Diabetes that is active but no longer recruiting, run by University of California, San Diego. The registered enrollment target is 30 participants, below the 824-participant average among 178 other Type 1 Diabetes trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04779645, a Phase 2 study of Type 1 Diabetes, is active but no longer recruiting, sponsored by University of California, San Diego.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This study will examine the effects a Glucagon Receptor Antagonist (GRA), has on Insulin Sensitivity, Cardiovascular risks (CVD), and Ketone body formation in participants with Type 1 diabetes. The participants will complete blood tests, tests to measure energy expenditure, CVD risks, and insulin resistance. These tests will be performed prior to start of treatment and again after 12-weeks of treatment with the GRA (called REMD-477).

Conditions Studied

Type 1 Diabetes

Interventions

  • DRUG Placebo
  • DRUG REMD-477

Study Locations (1)

California

  • UC San Diego Altman Clinical & Translational Research Institute - La Jolla

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2021-07-31
Est. Completion 2025-12-31
Phase Phase 2

Sponsor

University of California, San Diego

775 total trials

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What the Registry Record Tells You About NCT04779645

The ClinicalTrials.gov registry entry for NCT04779645 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 824-participant average among 178 other Type 1 Diabetes trials with a reported enrollment target (96% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Type 1 Diabetes appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04779645 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT04779645 about?

NCT04779645 is a clinical study titled "Effects of GRA in Patients With Type 1". This study will examine the effects a Glucagon Receptor Antagonist (GRA), has on Insulin Sensitivity, Cardiovascular risks (CVD), and Ketone body formation in participants with Type 1 diabetes. The participants will complete blood tests, tests to measure energy expenditure, CVD risks, and insulin re...

What is the current status of trial NCT04779645?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2021-07-31. Estimated completion is 2025-12-31.

What conditions does trial NCT04779645 study?

This clinical trial studies the following conditions: Type 1 Diabetes.

What interventions are being tested in trial NCT04779645?

The interventions under investigation include: Placebo (DRUG), REMD-477 (DRUG).

Who is sponsoring clinical trial NCT04779645?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04779645 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.