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A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy
NCT05463744 · View on ClinicalTrials.gov ↗
Study Summary
The main purpose of this study is to measure the safety and efficacy of insulin efsitora alfa (LY3209590) compared with insulin degludec in participants with type 1 diabetes treated with multiple daily injection therapy.
Conditions Studied
Interventions
- DRUG Insulin Degludec
- DRUG Insulin Efsitora Alfa
Study Locations (20)
California
- John Muir Physician Network Research Center — Concord
- Valley Research — Fresno
- Catalina Research Institute, LLC — Montclair
- Sansum Diabetes Research Institute — Santa Barbara
- University Clinical Investigators, Inc. — Tustin
Florida
- Northeast Research Institute (NERI) — Fleming Island
- Jellinger and Lerman, MD PA dba The Center for Diabetes and Endocrine Care — Fort Lauderdale
- Suncoast Clinical Research, Inc. — New Port Richey
- Hanson Clinical Research Center — Port Charlotte
Maryland
- MedStar Health Research Institute (MedStar Physician Based Research Network) — Hyattsville
- Endocrine and Metabolic Consultants — Rockville
Nevada
- Palm Research Center Tenaya — Las Vegas
- Palm Research Center Sunset — Las Vegas
Colorado
- University of Colorado Anschutz Medical Campus — Aurora
Georgia
- East Coast Institute for Research at The Jones Center — Macon
Hawaii
- East-West Medical Research Institute — Honolulu
Idaho
- Rocky Mountain Clinical Research — Idaho Falls
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 692 participants |
| Start Date | 2022-08-12 |
| Est. Completion | 2024-05-07 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05463744
The ClinicalTrials.gov registry entry for NCT05463744 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 692 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Diabetes appearing as the primary indexed condition, and to 2 interventions — of which Insulin Degludec is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05463744 reports 20 study locations spanning 11 distinct geographic areas — top geographies include California, Florida, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05463744 about?
NCT05463744 is a clinical study titled "A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy". The main purpose of this study is to measure the safety and efficacy of insulin efsitora alfa (LY3209590) compared with insulin degludec in participants with type 1 diabetes treated with multiple daily injection therapy.
What is the current status of trial NCT05463744?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 692 participants. The study started on 2022-08-12. Estimated completion is 2024-05-07.
What conditions does trial NCT05463744 study?
This clinical trial studies the following conditions: Diabetes, Type 1 Diabetes. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05463744?
The interventions under investigation include: Insulin Degludec (DRUG), Insulin Efsitora Alfa (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05463744?
This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05463744 being conducted?
This trial has 20 study locations across California, Colorado, Florida, Georgia, Hawaii. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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