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ClinicalTrials.gov 69 recruiting now official registry

Type 1 Diabetes clinical trials

69 of 179 indexed Type 1 Diabetes trials are currently recruiting.

179 US clinical trials · 69 currently recruiting

Type 1 Diabetes is the subject of 179 registered US clinical trials on ClinicalTrials.gov, 69 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 14 of these trials.

The research picture

Type 1 Diabetes has 179 registered US clinical trials, 69 of them open to new participants right now, about 39% of the total.

69
recruiting participants now
39%
of trials open to enrollment
19
in Phase 3–4 (later-stage)
14
top sponsor: University of Colorado, Denver
Phase 127Phase 223Phase 310Phase 49

Active & Recent Trials

179 total, page 4 of 4

COMPLETED NA 21 participants

Reactive Oxygen Species in the Pathogenesis of Diabetic Complications

Albert Einstein College of Medicine

NCT00703989

COMPLETED Early Phase 1 20 participants

Immune Effects of Vedolizumab With or Without Anti-TNF Pre-treatment in T1D

Benaroya Research Institute

NCT05281614

COMPLETED Phase 2 20 participants

An Outpatient Pump Shutoff Pilot Feasibility and Safety Study

Jaeb Center for Health Research

NCT01736930

COMPLETED Phase 3 20 participants

The Effect of Prolonged Pramlintide Infusion in Pediatric Diabetes

Baylor College of Medicine

NCT00206297

COMPLETED NA 18 participants

Web-Based Simulation Tool For Self-Management Support In Type 1 Diabetes Mellitus

University of Virginia

NCT04439903

COMPLETED Phase 1 17 participants

Study of the Acute Metabolic Effect of Exenatide in Type 1 Diabetes

Yale University

NCT01855490

COMPLETED 16 participants

Support Group Surveys for Individuals Who Have Type 1 Diabetes and an Eating Disorder

HealthPartners Institute

NCT00818142

COMPLETED Phase 1 16 participants

Evaluating the Benefits of Physiologic Insulin Delivery

Stanford University

NCT04416737

COMPLETED NA 15 participants

Evaluation of The Postprandial Impact of Automated Priming Bolus for Full Closed Loop Insulin Delivery

Marc Breton

NCT05528770

COMPLETED Phase 1 15 participants

Cord Blood Plus Vitamin D and Omega 3s in T1D

University of Florida

NCT00873925

COMPLETED NA 14 participants

Artificial Pancreas With Different Stress Assessments in the Outpatient Setting

Sansum Diabetes Research Institute

NCT04142229

COMPLETED Phase 2 14 participants

Sensor-Augmented Insulin Delivery: Insulin Plus Glucagon Versus Insulin Alone

Legacy Health System

NCT00797823

COMPLETED Phase 1 14 participants

Islet Transplantation in Type 1 Diabetic Patients

University of Wisconsin, Madison

NCT00214253

COMPLETED NA 13 participants

Use of Continuous Glucose Monitoring System With Intensive Feedback in Adolescents With Poorly Controlled Type 1 Diabetes

NYU Langone Health

NCT03020069

COMPLETED Early Phase 1 13 participants

Acceleration of Insulin Action by Hyaluronidase During Closed-Loop Therapy

Yale University

NCT01945099

COMPLETED Phase 1 12 participants

Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function

Indiana University

NCT04114357

COMPLETED Phase 1 12 participants

Combination GRA and SGLT-2i Treatment in Type 1 Diabetes

University of California, San Diego

NCT04545411

COMPLETED NA 12 participants

Pilot Study of Closed-Loop Glucose Control in People With Type 1 Diabetes (BPK004)

University of Virginia

NCT00977808

COMPLETED 12 participants

Exercise and Diabetes - an Observational Study of Exercise and Blood Glucose Control

Sansum Diabetes Research Institute

NCT02190669

COMPLETED Phase 2 10 participants

Measurement of Glucose/Glycogen Metabolism in Humans Using Magnetic Resonance at 4 or 7 Tesla

University of Minnesota

NCT00786825

COMPLETED NA 10 participants

Effect of Canagliflozin in T1DM (Type 1 Diabetes Melitus) After Interruption of Continuous Subcutaneous Insulin Infusion

Yale University

NCT02673138

COMPLETED Phase 1 10 participants

Autologous Dendritic Cell Therapy for Type 1 Diabetes Suppression: A Safety Study

University of Pittsburgh

NCT00445913

COMPLETED NA 10 participants

Pramlintide in Adolescents With Type 1 Diabetes

University of Colorado, Denver

NCT00842075

COMPLETED Phase 2 9 participants

Cognitive Behavioral Therapy (CBT) for Adherence and Depression in Type 1 Diabetes

Massachusetts General Hospital

NCT01527981

COMPLETED NA 8 participants

Safety and Feasibility of a Low Carbohydrate Diet in Children With Type 1 Diabetes

Washington University School of Medicine

NCT04228822

COMPLETED Phase 2 8 participants

Pilot Study to Determine Effects of Salsalate in Type 1 Diabetes and Painful Peripheral Neuropathy

University of Michigan

NCT01480297

COMPLETED NA 7 participants

Pharmacokinetics (PK)/ Pharmacodynamics (PD) of an Extended Wear Infusion Set for Continuous Subcutaneous Insulin Infusion (CSII) in Type 1 Diabetes Mellitus (T1DM) Patients ("PEXIS")

Capillary Biomedical

NCT04398030

COMPLETED Phase 1 6 participants

hOKT3γ1 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients

University of Minnesota

NCT00285194

COMPLETED Phase 3 5 participants

Liraglutide in Adolescents With Type 1 Diabetes

University at Buffalo

NCT02516657

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Phase Distribution

PhaseTrial count
Phase 1 27
Phase 2 23
Phase 3 10
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Type 1 Diabetes Trial Landscape

179 indexed Type 1 Diabetes studies · 69 recruiting (39%).

Phase mix: 19 late (III/IV) vs 50 early (I/II).

Top sponsor: University of Colorado, Denver (14 trials), 9 others listed. 29 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Type 1 Diabetes?

PlainTrial tracks 179 US clinical trials for Type 1 Diabetes, of which 69 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Type 1 Diabetes?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.