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Type 1 Diabetes clinical trials
69 of 179 indexed Type 1 Diabetes trials are currently recruiting.
179 US clinical trials · 69 currently recruiting
Type 1 Diabetes is the subject of 179 registered US clinical trials on ClinicalTrials.gov, 69 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 14 of these trials.
The research picture
Type 1 Diabetes has 179 registered US clinical trials, 69 of them open to new participants right now, about 39% of the total.
- 69
- recruiting participants now
- 39%
- of trials open to enrollment
- 19
- in Phase 3–4 (later-stage)
- 14
- top sponsor: University of Colorado, Denver
Active & Recent Trials
179 total, page 4 of 4
Reactive Oxygen Species in the Pathogenesis of Diabetic Complications
Albert Einstein College of Medicine
NCT00703989
Immune Effects of Vedolizumab With or Without Anti-TNF Pre-treatment in T1D
Benaroya Research Institute
NCT05281614
An Outpatient Pump Shutoff Pilot Feasibility and Safety Study
Jaeb Center for Health Research
NCT01736930
The Effect of Prolonged Pramlintide Infusion in Pediatric Diabetes
Baylor College of Medicine
NCT00206297
Web-Based Simulation Tool For Self-Management Support In Type 1 Diabetes Mellitus
University of Virginia
NCT04439903
Study of the Acute Metabolic Effect of Exenatide in Type 1 Diabetes
Yale University
NCT01855490
Support Group Surveys for Individuals Who Have Type 1 Diabetes and an Eating Disorder
HealthPartners Institute
NCT00818142
Evaluating the Benefits of Physiologic Insulin Delivery
Stanford University
NCT04416737
Evaluation of The Postprandial Impact of Automated Priming Bolus for Full Closed Loop Insulin Delivery
Marc Breton
NCT05528770
Cord Blood Plus Vitamin D and Omega 3s in T1D
University of Florida
NCT00873925
Artificial Pancreas With Different Stress Assessments in the Outpatient Setting
Sansum Diabetes Research Institute
NCT04142229
Sensor-Augmented Insulin Delivery: Insulin Plus Glucagon Versus Insulin Alone
Legacy Health System
NCT00797823
Islet Transplantation in Type 1 Diabetic Patients
University of Wisconsin, Madison
NCT00214253
Use of Continuous Glucose Monitoring System With Intensive Feedback in Adolescents With Poorly Controlled Type 1 Diabetes
NYU Langone Health
NCT03020069
Acceleration of Insulin Action by Hyaluronidase During Closed-Loop Therapy
Yale University
NCT01945099
Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function
Indiana University
NCT04114357
Combination GRA and SGLT-2i Treatment in Type 1 Diabetes
University of California, San Diego
NCT04545411
Pilot Study of Closed-Loop Glucose Control in People With Type 1 Diabetes (BPK004)
University of Virginia
NCT00977808
Exercise and Diabetes - an Observational Study of Exercise and Blood Glucose Control
Sansum Diabetes Research Institute
NCT02190669
Measurement of Glucose/Glycogen Metabolism in Humans Using Magnetic Resonance at 4 or 7 Tesla
University of Minnesota
NCT00786825
Effect of Canagliflozin in T1DM (Type 1 Diabetes Melitus) After Interruption of Continuous Subcutaneous Insulin Infusion
Yale University
NCT02673138
Autologous Dendritic Cell Therapy for Type 1 Diabetes Suppression: A Safety Study
University of Pittsburgh
NCT00445913
Pramlintide in Adolescents With Type 1 Diabetes
University of Colorado, Denver
NCT00842075
Cognitive Behavioral Therapy (CBT) for Adherence and Depression in Type 1 Diabetes
Massachusetts General Hospital
NCT01527981
Safety and Feasibility of a Low Carbohydrate Diet in Children With Type 1 Diabetes
Washington University School of Medicine
NCT04228822
Pilot Study to Determine Effects of Salsalate in Type 1 Diabetes and Painful Peripheral Neuropathy
University of Michigan
NCT01480297
Pharmacokinetics (PK)/ Pharmacodynamics (PD) of an Extended Wear Infusion Set for Continuous Subcutaneous Insulin Infusion (CSII) in Type 1 Diabetes Mellitus (T1DM) Patients ("PEXIS")
Capillary Biomedical
NCT04398030
hOKT3γ1 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients
University of Minnesota
NCT00285194
Liraglutide in Adolescents With Type 1 Diabetes
University at Buffalo
NCT02516657
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 27 |
| Phase 2 | 23 |
| Phase 3 | 10 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Type 1 Diabetes Trial Landscape
179 indexed Type 1 Diabetes studies · 69 recruiting (39%).
Phase mix: 19 late (III/IV) vs 50 early (I/II).
Top sponsor: University of Colorado, Denver (14 trials), 9 others listed. 29 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Type 1 Diabetes?
PlainTrial tracks 179 US clinical trials for Type 1 Diabetes, of which 69 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Type 1 Diabetes?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.