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NCT03005418 · ClinicalTrials.gov registry record · Phase 2

Humacyte Human Acellular Vessel (HAV) in Patients With Vascular Trauma

A Phase 2 study of Trauma and Vascular System Injury, sponsored by Humacyte.

Active
Registry status
Phase 2
Development phase
72
Enrollment target
20
Study locations

NCT03005418 is a Phase 2 study of Trauma and Vascular System Injury that is active but no longer recruiting, run by Humacyte. The registered enrollment target is 72 participants, below the 306-participant average among 56 other Trauma trials with a reported enrollment target (76% lower). The trial reports 20 study locations across 9 states.

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The verdict

NCT03005418, a Phase 2 study of Trauma and Vascular System Injury, is active but no longer recruiting, sponsored by Humacyte.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
72 participants
Enrollment target
20
Study locations

Study Summary

This study evaluates the use of the Human Acellular Vessel (HAV) in adults with vascular trauma below the neck who are undergoing vascular reconstructive surgery. There will be a torso cohort and a limb cohort. All subjects will be implanted with a HAV as an interposition vessel or bypass using standard vascular surgical techniques. There is no control arm.

Interventions

  • BIOLOGICAL Human Acellular Vessel (HAV)

Study Locations (20)

California

  • Jacob Medical Center at UC San Diego - La Jolla
  • Keck Hospital of University of Southern California (USC) - Los Angeles
  • Cedars-Sinai Medical Cener - Los Angeles
  • UCI Medical Center - Orange
  • University California, Davis - Sacramento
  • University of California San Diego (UCSD) Medical Center - San Diego

Florida

  • UF Health Jacksonville - Jacksonville
  • Jackson South Medical Center - Miami
  • Ryder Trauma Center - Miami
  • Tampa General Hospital - Tampa

Maryland

  • R Adams Cowley Baltimore Shock Trauma - Baltimore
  • Johns Hopkins Bayview Medical Center - Baltimore
  • Johns Hopkins Hospital - Baltimore

New Jersey

  • Cooper University Hospital - Camden
  • Rutgers New Jersey Medical School - Newark

Colorado

  • Ernest E Moore Shock Trauma Center at Denver Health - Denver

Georgia

  • Grady Memorial Hospital - Atlanta

Minnesota

  • Mayo Clinic - Rochester

Missouri

  • Saint Louis University (SLU) - St Louis

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2018-09-01
Est. Completion 2027-09-01
Phase Phase 2

Sponsor

Humacyte

6 total trials

What the Registry Record Tells You About NCT03005418

The ClinicalTrials.gov registry entry for NCT03005418 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 306-participant average among 56 other Trauma trials with a reported enrollment target (76% lower). The listed sponsor is Humacyte, which has 6 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Trauma appearing as the primary indexed condition, and to 1 intervention - of which Human Acellular Vessel (HAV) is the first listed.

NCT03005418 reports 20 study locations spanning 9 distinct geographic areas - top geographies include California, Florida, Maryland.

Frequently Asked Questions

What is clinical trial NCT03005418 about?

NCT03005418 is a clinical study titled "Humacyte Human Acellular Vessel (HAV) in Patients With Vascular Trauma". This study evaluates the use of the Human Acellular Vessel (HAV) in adults with vascular trauma below the neck who are undergoing vascular reconstructive surgery. There will be a torso cohort and a limb cohort. All subjects will be implanted with a HAV as an interposition vessel or bypass using stan...

What is the current status of trial NCT03005418?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 72 participants. The study started on 2018-09-01. Estimated completion is 2027-09-01.

What conditions does trial NCT03005418 study?

This clinical trial studies the following conditions: Trauma, Vascular System Injury.

What interventions are being tested in trial NCT03005418?

The interventions under investigation include: Human Acellular Vessel (HAV) (BIOLOGICAL).

Who is sponsoring clinical trial NCT03005418?

This trial is sponsored by Humacyte, which has 6 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03005418 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.