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NCT06606119 · ClinicalTrials.gov registry record
The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma
A clinical trial of Critical Illness and Trauma, sponsored by University of Florida.
- Recruiting
- Registry status
- 275
- Enrollment target
- 3
- Study locations
NCT06606119 is a study of Critical Illness and Trauma that is actively recruiting participants, run by University of Florida. The registered enrollment target is 275 participants, below the 3,135-participant average among 91 other Critical Illness trials with a reported enrollment target (91% lower). The trial reports 3 study locations across 1 state.
The verdict
NCT06606119, a study of Critical Illness and Trauma, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- 275 participants
- Enrollment target
- 3
- Study locations
Study Summary
Traumatic injury followed by critical illness provokes pathophysiologic changes in the bone marrow and the gut that contribute to persistent anemia and changes in the microbiome which significantly impact long-term recovery. This project will define the interactions between the stress, chronic inflammation, bone marrow dysfunction, and an altered microbiome which will provide a strong foundation for future clinical interventions to help improve outcomes following severe trauma.
Conditions Studied
Interventions
- OTHER Data and tissue collection
Study Locations (3)
Florida
- UF Academic Research Building - Gainesville
- UF Health at Shands Hospital - Gainesville
- UF Laboratory of Inflammation Biology and Surgical Science and Shands Hospital at UF - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 275 participants |
| Start Date | 2025-01-24 |
| Est. Completion | 2028-10-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06606119
The ClinicalTrials.gov registry entry for NCT06606119 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 275 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,135-participant average among 91 other Critical Illness trials with a reported enrollment target (91% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with Critical Illness appearing as the primary indexed condition, and to 1 intervention - of which Data and tissue collection is the first listed.
NCT06606119 reports 3 study locations spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT06606119 about?
NCT06606119 is a clinical study titled "The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma". Traumatic injury followed by critical illness provokes pathophysiologic changes in the bone marrow and the gut that contribute to persistent anemia and changes in the microbiome which significantly impact long-term recovery. This project will define the interactions between the stress, chronic infla...
What is the current status of trial NCT06606119?
This trial is currently recruiting. The enrollment target is 275 participants. The study started on 2025-01-24. Estimated completion is 2028-10-01.
What conditions does trial NCT06606119 study?
This clinical trial studies the following conditions: Critical Illness, Trauma, Trauma Injury, Microbiome, Acute Blood Loss Anemia.
What interventions are being tested in trial NCT06606119?
The interventions under investigation include: Data and tissue collection (OTHER).
Who is sponsoring clinical trial NCT06606119?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06606119 being conducted?
This trial has 3 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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