Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07290634 · ClinicalTrials.gov registry record

Comparative Outcomes of PCC and Recombinant Activated Factor VIIa in Trauma-Associated Massive Transfusion

A clinical trial of Trauma and Thromboembolus, sponsored by Zeliha Alicikus.

Recruiting
Registry status
4
Enrollment target
2
Study locations

NCT07290634: Recruiting study of Trauma and Thromboembolus, sponsored by Zeliha Alicikus.

NCT07290634 is a study of Trauma and Thromboembolus that is actively recruiting participants, run by Zeliha Alicikus. The registered enrollment target is 4 participants, below the 307-participant average among 56 other Trauma trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07290634, a study of Trauma and Thromboembolus, is actively recruiting participants, sponsored by Zeliha Alicikus.

RECRUITING
Registry status
4 participants
Enrollment target
2
Study locations

Study Summary

This study aims to compare the incidence of thromboembolic complications among trauma patients receiving PCC, rFVIIa, both agents, or neither during massive transfusion. Secondary objectives include comparing mortality, transfusion requirements, intensive care unit (ICU) and hospital length of stay, ventilator-free days, and the incidence of transfusion-associated adverse events such as transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO). Subgroup analyses will evaluate outcomes in patients with and without laboratory-confirmed TIC (INR \>1.2).

Primary Outcome

Number of Participants with venous thrombosis, pulmonary embolism, ischemic stroke, mesenteric ischemia

Conditions Studied

Trauma Thromboembolus Massive Blood Transfusion; Thrombocytopenia

Interventions

  • PROCEDURE Number of Participants with massive blood transfusion

Study Locations (2)

Florida

  • UF Health Jacksonville (Shands Hospital) - Jacksonville
  • UF Health Jacksonville (Shands Hospital) - Jacksonville

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2026-01-30
Est. Completion 2026-06-30
Zeliha Alicikus

2 total trials

What NCT07290634 shows while recruiting

NCT07290634 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 307-participant average among 56 other Trauma trials with a reported enrollment target (99% lower).

The record links to 3 conditions, with Trauma appearing as the primary indexed condition, and to 1 intervention - of which Number of Participants with massive blood transfusion is the first listed.

NCT07290634 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT07290634 about?

NCT07290634 is a clinical study titled "Comparative Outcomes of PCC and Recombinant Activated Factor VIIa in Trauma-Associated Massive Transfusion". This study aims to compare the incidence of thromboembolic complications among trauma patients receiving PCC, rFVIIa, both agents, or neither during massive transfusion. Secondary objectives include comparing mortality, transfusion requirements, intensive care unit (ICU) and hospital length of stay,...

What is the current status of trial NCT07290634?

This trial is currently recruiting. The enrollment target is 4 participants. The study started on 2026-01-30. Estimated completion is 2026-06-30.

What conditions does trial NCT07290634 study?

This clinical trial studies the following conditions: Trauma, Thromboembolus, Massive Blood Transfusion; Thrombocytopenia.

What interventions are being tested in trial NCT07290634?

The interventions under investigation include: Number of Participants with massive blood transfusion (PROCEDURE).

Who is sponsoring clinical trial NCT07290634?

This trial is sponsored by Zeliha Alicikus, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07290634 being conducted?

This trial has 2 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Trauma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07290634's enrollment target sits among peer trials

4 57th of 56 the lowest of 56 other Trauma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Trauma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

More recruiting context for NCT07290634

Source: ClinicalTrials.gov NCT07290634, the US trial registry maintained by the National Library of Medicine. NCT07290634 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.