Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05958342 · ClinicalTrials.gov registry record · Phase 2
CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial
A Phase 2 study of Trauma and Hemorrhage, sponsored by Jason Sperry.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 1,050
- Enrollment target
- 13
- Study locations
NCT05958342: Recruiting Phase 2 study of Trauma and Hemorrhage, sponsored by Jason Sperry.
NCT05958342 is a Phase 2 study of Trauma and Hemorrhage that is actively recruiting participants, run by Jason Sperry. The registered enrollment target is 1,050 participants, above the 289-participant average among 56 other Trauma trials with a reported enrollment target (263% higher). The trial reports 13 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05958342, a Phase 2 study of Trauma and Hemorrhage, is actively recruiting participants, sponsored by Jason Sperry.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 1,050 participants
- Enrollment target
- 13
- Study locations
Study Summary
The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) Trial is a proposed 4 year, double-blind, mutli-center, prehospital and early in hospital phase randomized trial designed to determine the efficacy and safety of prehospital calcium and early in hospital vasopressin in patients at risk of hemorrhagic shock.
Primary Outcome
all cause mortality within 30 days
Conditions Studied
Interventions
- DRUG Calcium Gluconate
- DRUG Vasopressin
- DRUG saline placebo
Study Locations (13)
Pennsylvania
- Allegheny Health Network - Pittsburgh
- University of Pittsburgh - Pittsburgh
Arizona
- University of Arizona - Tucson
Arkansas
- University of Arkansas for Medical Sciences - Little Rock
California
- Zuckerberg San Francisco General Hospital and Trauma Center at University of California, San Francisco - San Francisco
Colorado
- Denver Health Medical Center - Denver
Florida
- University of Miami - Miami
Minnesota
- Hennepin County Medical Center - Minneapolis
Missouri
- University of Missouri Health Care - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,050 participants |
| Start Date | 2024-06-30 |
| Est. Completion | 2028-03 |
| Phase | Phase 2 |
What NCT05958342 shows while recruiting
NCT05958342 is an interventional study that assigns participants to a tested intervention. Its 1,050 participants enrollment target places it among the larger protocols in the corpus, above the 289-participant average among 56 other Trauma trials with a reported enrollment target (263% higher).
The record links to 2 conditions, with Trauma appearing as the primary indexed condition, and to 3 interventions - of which Calcium Gluconate is the first listed.
NCT05958342 lists 13 locations in 12 states (Pennsylvania, Arizona, Arkansas).
Frequently Asked Questions
What is clinical trial NCT05958342 about?
NCT05958342 is a clinical study titled "CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial". The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) Trial is a proposed 4 year, double-blind, mutli-center, prehospital and early in hospital phase randomized trial designed to determine the efficacy and safety of prehospital calcium and early in hospital vasopressin in patie...
What is the current status of trial NCT05958342?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 1,050 participants. The study started on 2024-06-30. Estimated completion is 2028-03.
What conditions does trial NCT05958342 study?
This clinical trial studies the following conditions: Trauma, Hemorrhage.
What interventions are being tested in trial NCT05958342?
The interventions under investigation include: Calcium Gluconate (DRUG), Vasopressin (DRUG), saline placebo (DRUG).
Who is sponsoring clinical trial NCT05958342?
This trial is sponsored by Jason Sperry, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05958342 being conducted?
This trial has 13 study locations across Arizona, Arkansas, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Trauma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05958342's enrollment target sits among peer trials
1,050 4th of 56 higher than 53 of 56 other Trauma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Trauma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients
RECRUITING · Phase 2
-
MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome
RECRUITING · Phase 2
-
Humacyte Human Acellular Vessel (HAV) in Patients With Vascular Trauma
ACTIVE NOT RECRUITING · Phase 2
-
Testing FIRST in Youth Outpatient Psychotherapy
RECRUITING · NA
-
PRESERVE & CONNECT: Impact Study of the BPC
RECRUITING · NA
-
Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04505618 · 1,050 participants · NA
Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease
- NCT04511806 · 1,050 participants
Childhood Cancer Predisposition Study (CCPS)
- NCT05028972 · 1,050 participants · NA
Hearing Impairment, Strategies and Outcomes in VA Emergency Departments
- NCT05915377 · 1,050 participants · NA
Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI