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NCT03828604 · ClinicalTrials.gov registry record · NA

Stress-Induced Inflammation and Reward Processing

A NA study of Stress, Psychological, sponsored by University of California, Los Angeles.

Completed
Registry status
NA
Development phase
57
Enrollment target
1
Study location

NCT03828604 is a NA study of Stress, Psychological that has completed, run by University of California, Los Angeles. The registered enrollment target is 57 participants, below the 170-participant average among 43 other Stress, Psychological trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03828604, a NA study of Stress, Psychological, has completed, sponsored by University of California, Los Angeles.

COMPLETED
Registry status
NA
Development phase
57 participants
Enrollment target
1
Study location

Study Summary

Anhedonia, or loss of interest or pleasure, is a key feature of depression and transdiagnostic construct in psychopathology. Both theory and compelling evidence from preclinical models implicates stress-induced inflammation as a key psychobiological pathway to anhedonic behavior; however, this pathway has not been demonstrated in human models. Further, although anhedonia may reflect dysregulation in multiple dimensions of reward, the extent to which stress-induced inflammation alters these dimensions is unclear. The current placebo controlled study used a standardized laboratory stressor task to elicit an inflammatory response in a sample of a healthy young women and evaluate effects of stress-induced inflammation on multiple behavioral indices of reward processing.

Conditions Studied

Interventions

  • BEHAVIORAL Stress; Trier Social Stress Task
  • BEHAVIORAL Placebo Trier Social Stress Task

Study Locations (1)

California

  • Clinical and Translational Research Center, University of California, Los Angeles - Los Angeles

Trial Details

FieldValue
Enrollment Target 57 participants
Start Date 2017-05-12
Est. Completion 2018-05-09
Phase NA

What the Registry Record Tells You About NCT03828604

The ClinicalTrials.gov registry entry for NCT03828604 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 57 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 170-participant average among 43 other Stress, Psychological trials with a reported enrollment target (66% lower). The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Stress, Psychological appearing as the primary indexed condition, and to 2 interventions - of which Stress; Trier Social Stress Task is the first listed.

NCT03828604 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03828604 about?

NCT03828604 is a clinical study titled "Stress-Induced Inflammation and Reward Processing". Anhedonia, or loss of interest or pleasure, is a key feature of depression and transdiagnostic construct in psychopathology. Both theory and compelling evidence from preclinical models implicates stress-induced inflammation as a key psychobiological pathway to anhedonic behavior; however, this pathw...

What is the current status of trial NCT03828604?

This trial is currently completed. It is a NA study. The enrollment target is 57 participants. The study started on 2017-05-12. Estimated completion is 2018-05-09.

What conditions does trial NCT03828604 study?

This clinical trial studies the following conditions: Stress, Psychological.

What interventions are being tested in trial NCT03828604?

The interventions under investigation include: Stress; Trier Social Stress Task (BEHAVIORAL), Placebo Trier Social Stress Task (BEHAVIORAL).

Who is sponsoring clinical trial NCT03828604?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03828604 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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