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NCT02811445 · ClinicalTrials.gov registry record
Role of the Gut Microbiome on Lean Mass and Physical Function in Older Adults
A clinical trial of Sarcopenia, sponsored by Tufts University.
- Completed
- Registry status
- 29
- Enrollment target
- 1
- Study location
NCT02811445: Completed study of Sarcopenia, sponsored by Tufts University.
NCT02811445 is a study of Sarcopenia that has completed, run by Tufts University. The registered enrollment target is 29 participants, below the 80-participant average among 41 other Sarcopenia trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02811445, a study of Sarcopenia, has completed, sponsored by Tufts University.
- COMPLETED
- Registry status
- 29 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators recently published significant associations between circulating gut bacteria-related metabolites with lean and skeletal muscle mass and with measures of physical function in older adults, evidence that suggests a role for gut bacteria on the maintenance of these outcomes. To date, studies aimed at identification of associations between gut bacteria with lean mass or with specific measures of physical function have yet to be reported. Accordingly, the over-arching hypothesis is that gut bacteria are associated with, and are causatively involved in mechanisms that underlie the maintenance of lean mass and physical function in older adults. Results obtained from the proposed study are intended as the basis for future studies aimed at targeted modulation of the gut microflora, which may be a novel and innovative means for improving lean mass and physical function, and for addressing the public health priority of healthy aging in older adults.
Primary Outcome
%WBLM measured with dual x-ray absorptiometry (DXA). A higher %WBLM is indicative of a higher amount of whole-body lean mass, when compared with lower values.
Conditions Studied
Study Locations (1)
Massachusetts
- Tufts University - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2016-05 |
| Est. Completion | 2019-11-01 |
What the finished NCT02811445 record still lists
NCT02811445 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 80-participant average among 41 other Sarcopenia trials with a reported enrollment target (64% lower).
The record links to 1 condition, with Sarcopenia appearing as the primary indexed condition, and to 0 interventions.
NCT02811445 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02811445 about?
NCT02811445 is a clinical study titled "Role of the Gut Microbiome on Lean Mass and Physical Function in Older Adults". The investigators recently published significant associations between circulating gut bacteria-related metabolites with lean and skeletal muscle mass and with measures of physical function in older adults, evidence that suggests a role for gut bacteria on the maintenance of these outcomes. To date, ...
What is the current status of trial NCT02811445?
This trial is currently completed. The enrollment target is 29 participants. The study started on 2016-05. Estimated completion is 2019-11-01.
What conditions does trial NCT02811445 study?
This clinical trial studies the following conditions: Sarcopenia.
Who is sponsoring clinical trial NCT02811445?
This trial is sponsored by Tufts University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02811445 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02811445's enrollment target sits among peer trials
29 31st of 41 higher than 11 of 41 other Sarcopenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sarcopenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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