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NCT03595774 · ClinicalTrials.gov registry record · Phase 1
Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals
A Phase 1 study of Aging and Sarcopenia, sponsored by Indiana University.
- Completed
- Registry status
- Phase 1
- Development phase
- 13
- Enrollment target
- 1
- Study location
NCT03595774: Completed Phase 1 study of Aging and Sarcopenia, sponsored by Indiana University.
NCT03595774 is a Phase 1 study of Aging and Sarcopenia that has completed, run by Indiana University. The registered enrollment target is 13 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03595774, a Phase 1 study of Aging and Sarcopenia, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 13 participants
- Enrollment target
- 1
- Study location
Study Summary
Nitrate is a naturally-occurring substance found in foods, especially green leafy vegetables and beets. Increasing nitrate intake (by drinking beetroot juice (BRJ) has been shown to improve muscle function young and middle-aged subjects, athletes, and patients with heart failure. The purpose of this study is to determine whether dietary nitrate provides a similar benefit in older individuals, and if so, the optimal dose. We will be comparing the effects of ingesting BRJ containing a smaller or greater amount of nitrate versus the effects of a placebo (BRJ from which the nitrate has been removed).
Primary Outcome
Maximal knee extensor velocity determined using isokinetic dynamometry
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Beet root juice
Study Locations (1)
Indiana
- Indiana University School of Health and Human Sciences - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2018-09-01 |
| Est. Completion | 2021-07-31 |
| Phase | Phase 1 |
What the finished NCT03595774 record still lists
NCT03595774 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Aging appearing as the primary indexed condition, and to 1 intervention - of which Beet root juice is the first listed.
NCT03595774 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT03595774 about?
NCT03595774 is a clinical study titled "Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals". Nitrate is a naturally-occurring substance found in foods, especially green leafy vegetables and beets. Increasing nitrate intake (by drinking beetroot juice (BRJ) has been shown to improve muscle function young and middle-aged subjects, athletes, and patients with heart failure. The purpose of this...
What is the current status of trial NCT03595774?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2018-09-01. Estimated completion is 2021-07-31.
What conditions does trial NCT03595774 study?
This clinical trial studies the following conditions: Aging, Sarcopenia.
What interventions are being tested in trial NCT03595774?
The interventions under investigation include: Beet root juice (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03595774?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03595774 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03595774's enrollment target sits among peer trials
13 254th of 262 higher than 9 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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