Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01542892 · ClinicalTrials.gov registry record · NA
Efficacy of Nutritional Supplementation on Physical-activity Mediated Changes in Physical Functioning Older Adults at Risk for Mobility Disability (The VIVE2 Study)
A NA study of Sarcopenia, sponsored by Tufts University.
- Completed
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 2
- Study locations
NCT01542892: Completed NA study of Sarcopenia, sponsored by Tufts University.
NCT01542892 is a NA study of Sarcopenia that has completed, run by Tufts University. The registered enrollment target is 150 participants, above the 77-participant average among 41 other Sarcopenia trials with a reported enrollment target (95% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01542892, a NA study of Sarcopenia, has completed, sponsored by Tufts University.
- COMPLETED
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 2
- Study locations
Study Summary
Several trials have found that nutritional supplementation can elicit an increased rate of skeletal muscle protein synthesis following a single bout of exercise in both young and older individuals. However, there have been no studies that have investigated if nutritional supplementation and exercise can cause a sustained increase in physical functioning and fat free mass, particularly in older adults with functional limitations. This study will compare the effects of a nutritional supplement versus a placebo on exercise training induced changes in physical functioning older adults who are at risk for mobility disability.
Primary Outcome
The primary outcome will be the time to walk 400 meters, expressed as average gait speed during the 400 M walk. All participants must be able to walk 400 meters in \<15 minutes at walking at their normal speed. The 400 M walk will be assessed at baseline, 3-months, and 6-months, with the changes at 6-months being the primary outcome.
Conditions Studied
Interventions
- OTHER Exercise Intervention
- DIETARY_SUPPLEMENT Supplement Intervention
Study Locations (2)
Massachusetts
- Jean Mayer Human Nutrition Research Center on Aging at Tufts University - Boston
Other
- Uppsala University - Uppsala
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2011-10 |
| Est. Completion | 2014-08 |
| Phase | NA |
What the finished NCT01542892 record still lists
NCT01542892 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 77-participant average among 41 other Sarcopenia trials with a reported enrollment target (95% higher).
The record links to 1 condition, with Sarcopenia appearing as the primary indexed condition, and to 2 interventions - of which Exercise Intervention is the first listed.
NCT01542892 reports a single indexed study location in Massachusetts, Other.
Frequently Asked Questions
What is clinical trial NCT01542892 about?
NCT01542892 is a clinical study titled "Efficacy of Nutritional Supplementation on Physical-activity Mediated Changes in Physical Functioning Older Adults at Risk for Mobility Disability (The VIVE2 Study)". Several trials have found that nutritional supplementation can elicit an increased rate of skeletal muscle protein synthesis following a single bout of exercise in both young and older individuals. However, there have been no studies that have investigated if nutritional supplementation and exercise...
What is the current status of trial NCT01542892?
This trial is currently completed. It is a NA study. The enrollment target is 150 participants. The study started on 2011-10. Estimated completion is 2014-08.
What conditions does trial NCT01542892 study?
This clinical trial studies the following conditions: Sarcopenia.
What interventions are being tested in trial NCT01542892?
The interventions under investigation include: Exercise Intervention (OTHER), Supplement Intervention (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01542892?
This trial is sponsored by Tufts University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01542892 being conducted?
This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sarcopenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01542892's enrollment target sits among peer trials
150 6th of 41 higher than 36 of 41 other Sarcopenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sarcopenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients
RECRUITING · NA
-
Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
RECRUITING · NA
-
Strength Training and Resveratrol
RECRUITING · NA
-
Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment
RECRUITING · NA
-
Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX)
RECRUITING · NA
-
C-Protein in Fatigue and Aging
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00412594 · 150 participants · Phase 2
Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia
- NCT01484730 · 150 participants
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
- NCT01985919 · 150 participants
Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples
- NCT02016248 · 150 participants · NA
SBRT Boost for Unfavorable Prostate Cancer'
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia