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ClinicalTrials.gov 58 recruiting now official registry

Sarcoma clinical trials

58 of 129 indexed Sarcoma trials are currently recruiting.

129 US clinical trials · 58 currently recruiting

Sarcoma is the subject of 129 registered US clinical trials on ClinicalTrials.gov, 58 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 80 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 26 of these trials.

The research picture

Sarcoma has 129 registered US clinical trials, 58 of them open to new participants right now, about 45% of the total.

58
recruiting participants now
45%
of trials open to enrollment
10
in Phase 3–4 (later-stage)
26
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 137Phase 243Phase 38Phase 42

Active & Recent Trials

129 total, page 3 of 3

COMPLETED Phase 2 60 participants

S0344 Intralesional Resection in Treating Patients With Chondrosarcoma of the Bone

SWOG Cancer Research Network

NCT00096213

COMPLETED Phase 2 53 participants

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Memorial Sloan Kettering Cancer Center

NCT00474994

COMPLETED Phase 2 49 participants

Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of Osteosarcoma

Children's Oncology Group

NCT00066365

COMPLETED Phase 2 48 participants

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors

Sarcoma Alliance for Research through Collaboration

NCT00304083

COMPLETED Phase 1 47 participants

Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas

Mohammed M Milhem

NCT01106872

COMPLETED Phase 1 36 participants

Safety and Efficacy Study Using Rexin-G for Sarcoma

Epeius Biotechnologies

NCT00505713

COMPLETED Phase 2 35 participants

Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery

Memorial Sloan Kettering Cancer Center

NCT00004250

COMPLETED Phase 2 32 participants

Bevacizumab in Treating Patients With Angiosarcoma

Northwestern University

NCT00288015

COMPLETED Phase 1 30 participants

A Phase I Study of SU101 in Pediatric Patients With Refractory Malignancy

National Cancer Institute (NCI)

NCT00001573

COMPLETED Phase 1 30 participants

Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity

National Cancer Institute (NCI)

NCT00001577

COMPLETED Phase 2 29 participants

Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma

University of Michigan Rogel Cancer Center

NCT04076579

COMPLETED NA 28 participants

Using a Patient-Centered mHealth Intervention to Improve Adherence to Oral Anticancer Medications

Memorial Sloan Kettering Cancer Center

NCT02833246

COMPLETED Phase 1 28 participants

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Pediatric Brain Tumor Consortium

NCT00006246

COMPLETED Phase 2 22 participants

Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00024258

COMPLETED Phase 1 16 participants

Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors

Masonic Cancer Center, University of Minnesota

NCT00703638

COMPLETED Phase 1 15 participants

A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors

National Cancer Institute (NCI)

NCT02107963

COMPLETED Phase 2 12 participants

O6-benzylguanine and Carmustine in Treating Patients With Recurrent, Metastatic, or Locally Advanced Soft Tissue Sarcoma

University of Chicago

NCT00005066

COMPLETED Phase 1 11 participants

PET Imaging of Cancer Patients Using [18F]-SKI-249380, a Radiolabeled Dasatinib-Derivative

Memorial Sloan Kettering Cancer Center

NCT01916135

COMPLETED Phase 2 10 participants

Cytarabine in Treating Young Patients With Recurrent or Refractory Ewing's Sarcoma

Children's Oncology Group

NCT00470275

COMPLETED Phase 2 9 participants

Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT01492673

COMPLETED 8 participants

T2* MRI Analysis for Sarcoma

Bryan Allen

NCT03658343

COMPLETED 4 participants

A Qualitative Case Study of the Experiences of Children With Cancer as They Learn About Their Diagnosis and Treatment

St. Jude Children's Research Hospital

NCT02041689

COMPLETED NA 3 participants

PET/MR in Assessing Response to Neoadjuvant Radiation Therapy in the Tx of High Grade Sarcomas

UNC Lineberger Comprehensive Cancer Center

NCT03076333

COMPLETED Phase 1

Radiation Therapy With or Without SU5416 in Treating Patients With Soft Tissue Sarcoma

Radiation Therapy Oncology Group

NCT00023725

COMPLETED Phase 2

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

Eastern Cooperative Oncology Group

NCT00003308

COMPLETED Phase 2

Bortezomib in Treating Patients With Advanced or Metastatic Sarcoma

Memorial Sloan Kettering Cancer Center

NCT00027716

COMPLETED Phase 2

Docetaxel, Gemcitabine, and Filgrastim (G-CSF) or Pegfilgrastim in Treating Patients With Advanced, Persistent, or Recurrent Uterine Leiomyosarcoma

Gynecologic Oncology Group

NCT00101127

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Endometrial Cancer, Fallopian Tube Cancer, or Sarcoma of the Female Reproductive Tract

NYU Langone Health

NCT00003334

COMPLETED Phase 3

Doxorubicin in Treating Patients With AIDS-Related Kaposi's Sarcoma

Roswell Park Cancer Institute

NCT00002985

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Phase Distribution

PhaseTrial count
Phase 1 37
Phase 2 43
Phase 3 8
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Sarcoma Trial Landscape

129 indexed Sarcoma studies · 58 recruiting (45%).

Phase mix: 10 late (III/IV) vs 80 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (26 trials), 9 others listed. 29 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Sarcoma?

PlainTrial tracks 129 US clinical trials for Sarcoma, of which 58 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Sarcoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.