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Sarcoma clinical trials
58 of 129 indexed Sarcoma trials are currently recruiting.
129 US clinical trials · 58 currently recruiting
Sarcoma is the subject of 129 registered US clinical trials on ClinicalTrials.gov, 58 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 80 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 26 of these trials.
The research picture
Sarcoma has 129 registered US clinical trials, 58 of them open to new participants right now, about 45% of the total.
- 58
- recruiting participants now
- 45%
- of trials open to enrollment
- 10
- in Phase 3–4 (later-stage)
- 26
- top sponsor: Memorial Sloan Kettering Cancer Center
Active & Recent Trials
129 total, page 3 of 3
S0344 Intralesional Resection in Treating Patients With Chondrosarcoma of the Bone
SWOG Cancer Research Network
NCT00096213
Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas
Memorial Sloan Kettering Cancer Center
NCT00474994
Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of Osteosarcoma
Children's Oncology Group
NCT00066365
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors
Sarcoma Alliance for Research through Collaboration
NCT00304083
Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas
Mohammed M Milhem
NCT01106872
Safety and Efficacy Study Using Rexin-G for Sarcoma
Epeius Biotechnologies
NCT00505713
Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery
Memorial Sloan Kettering Cancer Center
NCT00004250
Bevacizumab in Treating Patients With Angiosarcoma
Northwestern University
NCT00288015
A Phase I Study of SU101 in Pediatric Patients With Refractory Malignancy
National Cancer Institute (NCI)
NCT00001573
Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity
National Cancer Institute (NCI)
NCT00001577
Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma
University of Michigan Rogel Cancer Center
NCT04076579
Using a Patient-Centered mHealth Intervention to Improve Adherence to Oral Anticancer Medications
Memorial Sloan Kettering Cancer Center
NCT02833246
Busulfan in Treating Children and Adolescents With Refractory CNS Cancer
Pediatric Brain Tumor Consortium
NCT00006246
Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors
Memorial Sloan Kettering Cancer Center
NCT00024258
Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT00703638
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
National Cancer Institute (NCI)
NCT02107963
O6-benzylguanine and Carmustine in Treating Patients With Recurrent, Metastatic, or Locally Advanced Soft Tissue Sarcoma
University of Chicago
NCT00005066
PET Imaging of Cancer Patients Using [18F]-SKI-249380, a Radiolabeled Dasatinib-Derivative
Memorial Sloan Kettering Cancer Center
NCT01916135
Cytarabine in Treating Young Patients With Recurrent or Refractory Ewing's Sarcoma
Children's Oncology Group
NCT00470275
Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma
Memorial Sloan Kettering Cancer Center
NCT01492673
T2* MRI Analysis for Sarcoma
Bryan Allen
NCT03658343
A Qualitative Case Study of the Experiences of Children With Cancer as They Learn About Their Diagnosis and Treatment
St. Jude Children's Research Hospital
NCT02041689
PET/MR in Assessing Response to Neoadjuvant Radiation Therapy in the Tx of High Grade Sarcomas
UNC Lineberger Comprehensive Cancer Center
NCT03076333
Radiation Therapy With or Without SU5416 in Treating Patients With Soft Tissue Sarcoma
Radiation Therapy Oncology Group
NCT00023725
Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma
Eastern Cooperative Oncology Group
NCT00003308
Bortezomib in Treating Patients With Advanced or Metastatic Sarcoma
Memorial Sloan Kettering Cancer Center
NCT00027716
Docetaxel, Gemcitabine, and Filgrastim (G-CSF) or Pegfilgrastim in Treating Patients With Advanced, Persistent, or Recurrent Uterine Leiomyosarcoma
Gynecologic Oncology Group
NCT00101127
Combination Chemotherapy in Treating Patients With Endometrial Cancer, Fallopian Tube Cancer, or Sarcoma of the Female Reproductive Tract
NYU Langone Health
NCT00003334
Doxorubicin in Treating Patients With AIDS-Related Kaposi's Sarcoma
Roswell Park Cancer Institute
NCT00002985
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 37 |
| Phase 2 | 43 |
| Phase 3 | 8 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Sarcoma Trial Landscape
129 indexed Sarcoma studies · 58 recruiting (45%).
Phase mix: 10 late (III/IV) vs 80 early (I/II).
Top sponsor: Memorial Sloan Kettering Cancer Center (26 trials), 9 others listed. 29 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Sarcoma?
PlainTrial tracks 129 US clinical trials for Sarcoma, of which 58 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Sarcoma?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.